Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans

Ingibjörg J Gudmundsdóttir; Ian L Megson; Jillian S Kell; Christopher A Ludlam; Keith A A Fox; David J Webb; David E Newby

doi:10.1161/CIRCULATIONAHA.106.638478

Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans

Ingibjörg J Gudmundsdóttir
, Ian L Megson
, Jillian S Kell
, Christopher A Ludlam
, Keith A A Fox
, David J Webb
, David E Newby

科研成果: Article › 同行评审

33 引用（Scopus）

摘要

Protease-activated receptor type 1 (PAR-1) has been proposed as the principal thrombin receptor in humans, although its actions in vivo have not been defined. The aim of the present study was to determine the direct vascular actions of PAR-1 agonism in humans.

源语言	English
页（从-至）	1625-32
页数	8
期刊	Circulation
卷	114
期	15
DOI	https://doi.org/10.1161/CIRCULATIONAHA.106.638478
出版状态	Published - 2006

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10.1161/CIRCULATIONAHA.106.638478

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title = "Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans",

abstract = "Protease-activated receptor type 1 (PAR-1) has been proposed as the principal thrombin receptor in humans, although its actions in vivo have not been defined. The aim of the present study was to determine the direct vascular actions of PAR-1 agonism in humans.",

author = "Gudmundsd{\'o}ttir, \{Ingibj{\"o}rg J\} and Megson, \{Ian L\} and Kell, \{Jillian S\} and Ludlam, \{Christopher A\} and Fox, \{Keith A A\} and Webb, \{David J\} and Newby, \{David E\}",

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AU - Gudmundsdóttir, Ingibjörg J

AU - Megson, Ian L

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AU - Ludlam, Christopher A

AU - Fox, Keith A A

AU - Webb, David J

AU - Newby, David E

PY - 2006

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AB - Protease-activated receptor type 1 (PAR-1) has been proposed as the principal thrombin receptor in humans, although its actions in vivo have not been defined. The aim of the present study was to determine the direct vascular actions of PAR-1 agonism in humans.

U2 - 10.1161/CIRCULATIONAHA.106.638478

DO - 10.1161/CIRCULATIONAHA.106.638478

M3 - Article

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SN - 1524-4539

VL - 114

SP - 1625

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JO - Circulation

JF - Circulation

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Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans

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