项目详细信息
Description of project aims
Specific types of T-cells are able to recognise portions of proteins displayed by melanoma cells, which illicits an immune response, leading to the destruction of tumour cells. Identification of the T-cells and the peptides they recognise increases our understanding of what types of features lead to an effective immune response capable of clearing tumours.
| 状态 | 活跃的 |
|---|---|
| 有效的开始/结束日期 | 1/08/17 → … |
联合国可持续发展目标
2015 年，联合国成员国同意 17 项全球可持续发展目标 (SDG)，以消除贫困、保护地球并确保全人类的繁荣。此项目有助于实现下列可持续发展目标：
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Good health and well being
指纹
搜索该项目所涉及的研究主题。这些标签是基于奖励/奖项生成的。它们共同形成唯一的指纹。
科研成果
- 6 Article
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Prolonged stable disease in a uveal melanoma patient with germline MBD4 nonsense mutation treated with pembrolizumab and ipilimumab
Johansson, P. A., Stark, A., Palmer, J. M., Bigby, K., Brooks, K., Rolfe, O., Pritchard, A. L., Whitehead, K., Warrier, S., Glasson, W. & Hayward, N. K., 1 5月 2019, 在: Immunogenetics. 71, 5-6, 页码 433-436 4 页码科研成果: Article › 同行评审
61 引用 （Scopus） -
Identifying neoantigens for use in immunotherapy
Hutchison, S. & Pritchard, A. L., 24 8月 2018, (E-pub ahead of print) 在: Mammalian Genome. 页码 1-17 17 页码科研成果: Article › 同行评审
开放访问文档40 引用 （Scopus）276 下载量 (Pure) -
Targeting Neoantigens for Personalised Immunotherapy
Pritchard, A. L., 1 4月 2018, 在: BioDrugs. 32, 2, 页码 99-109 11 页码科研成果: Article › 同行评审
开放访问文档11 引用 （Scopus）226 下载量 (Pure)