项目详细信息
Description of project aims
Genomic changes within tumours can help to drive the tumourigenic process. These alterations can be identified using next generation sequencing approaches and the effects of these changes are assessed using in vitro functional models.
| 状态 | 活跃的 |
|---|---|
| 有效的开始/结束日期 | 1/08/17 → … |
协作伙伴
- University of the Highlands and Islands （主要的）
- Oncogenomics Group, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
- National Cancer Institute (NCI), National Institute of Health (NIH), Bethesda, Maryland
- Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
- Melanoma Institute Australia
联合国可持续发展目标
2015 年，联合国成员国同意 17 项全球可持续发展目标 (SDG)，以消除贫困、保护地球并确保全人类的繁荣。此项目有助于实现下列可持续发展目标：
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Good health and well being
指纹
搜索该项目所涉及的研究主题。这些标签是基于奖励/奖项生成的。它们共同形成唯一的指纹。
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Pan-cancer analysis of whole genomes
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium & Pritchard, A., 5 2月 2020, 在: Nature. 578, 7793, 页码 82-93 12 页码科研成果: Article › 同行评审
开放访问文档2330 引用 （Scopus）116 下载量 (Pure) -
Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours
Johansson, P. A., Brooks, K., Newell, F., Palmer, J. M., Wilmott, J. S., Pritchard, A. L., Broit, N., Wood, S., Carlino, M. S., Leonard, C., Koufariotis, L. T., Nathan, V., Beasley, A. B., Howlie, M., Dawson, R., Rizos, H., Schmidt, C. W., Long, G. V., Hamilton, H. & Kiilgaard, J. F. 以及 15其他, , 15 5月 2020, 在: Nature Communications. 11, 页码 1-8 8 页码, 2408 (2020).科研成果: Article › 同行评审
开放访问文档126 引用 （Scopus）193 下载量 (Pure) -
Prolonged stable disease in a uveal melanoma patient with germline MBD4 nonsense mutation treated with pembrolizumab and ipilimumab
Johansson, P. A., Stark, A., Palmer, J. M., Bigby, K., Brooks, K., Rolfe, O., Pritchard, A. L., Whitehead, K., Warrier, S., Glasson, W. & Hayward, N. K., 1 5月 2019, 在: Immunogenetics. 71, 5-6, 页码 433-436 4 页码科研成果: Article › 同行评审
61 引用 （Scopus）