Tuning the Nitric Oxide Release from CPO-27 MOFs

Damiano Cattaneo; Stewart J Warrender; Morven J. Duncan; Christopher J Kelsall; Mary K Doherty; Phillip Whitfield; Ian Megson; Russell Morris

doi:10.1039/C5RA24023A

Tuning the Nitric Oxide Release from CPO-27 MOFs

Damiano Cattaneo
, Stewart J Warrender
, Morven J. Duncan
, Christopher J Kelsall
, Mary K Doherty
, Phillip Whitfield
, Ian Megson
, Russell Morris

Resultado de pesquisa: Article › revisão de pares

62 Citações (Scopus)

269 Transferências (Pure)

Resumo

Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

Idioma original	English
Páginas (de-até)	14059-14067
Número de páginas	8
Revista	RSC Adv.
Volume	17
Número de emissão	6
Data online antecipada	26 jan. 2016
DOIs	https://doi.org/10.1039/C5RA24023A
Estado da publicação	Published - 26 jan. 2016

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10.1039/C5RA24023ALicença: CC BY

Cattaneo_et_al_Tuning_the_Nitric_Oxide_Release_from_CPO_27_MOFS
© 2017 The Authors. Published by the Royal Society of Chemistry
Submitted manuscript, 2,54 MBLicença: CC BY
Tuning the nitric oxide release from CPO-27 MOFs
© 2017 The Authors. Published by the Royal Society of Chemistry
Final published version, 2,62 MBLicença: CC BY

http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C5RA24023ALicença: CC BY

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title = "Tuning the Nitric Oxide Release from CPO-27 MOFs",

abstract = "Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications",

author = "Damiano Cattaneo and Warrender, \{Stewart J\} and Duncan, \{Morven J.\} and Kelsall, \{Christopher J\} and Doherty, \{Mary K\} and Phillip Whitfield and Ian Megson and Russell Morris",

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AU - Cattaneo, Damiano

AU - Warrender, Stewart J

AU - Duncan, Morven J.

AU - Kelsall, Christopher J

AU - Doherty, Mary K

AU - Whitfield, Phillip

AU - Megson, Ian

AU - Morris, Russell

PY - 2016/1/26

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N2 - Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

AB - Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

U2 - 10.1039/C5RA24023A

DO - 10.1039/C5RA24023A

M3 - Article

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SP - 14059

EP - 14067

JO - RSC Adv.

JF - RSC Adv.

IS - 6

ER -

Tuning the Nitric Oxide Release from CPO-27 MOFs

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