Clearance of dying cells and autoimmunity

Sylwia Michlewska; Aisleen McColl; Adriano G Rossi; Ian L Megson; Ian Dransfield

doi:10.1080/08916930701357208

Clearance of dying cells and autoimmunity

Sylwia Michlewska
, Aisleen McColl
, Adriano G Rossi
, Ian L Megson
, Ian Dransfield

Resultado de pesquisa › revisão de pares

43 Citações (Scopus)

Resumo

Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.

Idioma original	English
Páginas (de-até)	267-73
Número de páginas	7
Revista	Autoimmunity
Volume	40
Número de emissão	4
DOIs	https://doi.org/10.1080/08916930701357208
Estado da publicação	Published - 2007

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10.1080/08916930701357208

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title = "Clearance of dying cells and autoimmunity",

abstract = "Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.",

author = "Sylwia Michlewska and Aisleen McColl and Rossi, \{Adriano G\} and Megson, \{Ian L\} and Ian Dransfield",

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journal = "Autoimmunity",

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T1 - Clearance of dying cells and autoimmunity

AU - Michlewska, Sylwia

AU - McColl, Aisleen

AU - Rossi, Adriano G

AU - Megson, Ian L

AU - Dransfield, Ian

PY - 2007

Y1 - 2007

N2 - Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.

AB - Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.

U2 - 10.1080/08916930701357208

DO - 10.1080/08916930701357208

M3 - Article

C2 - 17516208

SN - 0891-6934

VL - 40

SP - 267

EP - 273

JO - Autoimmunity

JF - Autoimmunity

IS - 4

ER -

Clearance of dying cells and autoimmunity

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