Research Publications

  1. 2018
  2. E-pub ahead of print

    MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells

    Valiño-Rivas, L., Cuarental, L., Agustin, M., Husi, H., Cannata-Ortiz, P., Sanz, A. B., Mischak, H., Ortiz, A. & Sanchez-Niño, M. D., 11 Dec 2018, In : Nephrology, Dialysis, Transplantation. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  3. Published

    The Many Facets of Fabry Disease in the Kidney-Heart Axis

    Fernandes, M. & Husi, H., 15 Nov 2018, In : Journal of Nephrology & Kidney Diseases . 1, 2, p. 1-4 4 p., 120.

    Research output: Contribution to journalArticle

  4. Published

    C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD)

    Fernandes, M., Patel, A. & Husi, H., 12 Nov 2018, In : PLoS ONE. 13, 11, p. 1-28 28 p., e0207371.

    Research output: Contribution to journalArticle

  5. Published

    Tapping all our Talents 2018

    Yellowlees, L., Arnold, P., Bell Burnell, J., Brown, A., Doherty, M. & Colquhoun, A., 12 Nov 2018, Edinburgh: The Royal Society of Edinburgh. 108 p.

    Research output: Book/ReportCommissioned report

  6. E-pub ahead of print

    The glycine lipids of Bacteroides thetaiotaomicron are important for fitness during growth in vivo and in vitro

    Lynch, A., Tammireddy, S. R., Doherty, M. K., Whitfield, P. D. & Clarke, D. J., 26 Oct 2018, In : Applied and Environmental Microbiology.

    Research output: Contribution to journalArticle

  7. E-pub ahead of print

    Identifying neoantigens for use in immunotherapy

    Hutchison, S. & Pritchard, A. L., 24 Aug 2018, In : Mammalian Genome. p. 1-17 17 p.

    Research output: Contribution to journalArticle

  8. Published

    Alteration of circulating natural autoantibodies to CD25-derived peptide antigens and FOXP3 in non-small cell lung cancer

    Zhao H, Zhang X, Han Z, Xie W, Yang W & Wei, J., 29 Jun 2018, In : Scientific Reports. 8, p. 1-8 8 p., 9847 (2018).

    Research output: Contribution to journalArticle

  9. Published

    A bedtime milk snack does not impact RMR, substrate utilisation and appetite the following morning in mildly overweight males

    Lay, A. H. H., Crabtree, D. R., Campbell, T. G., Dreczkowski, G. M., Galloway, S. D. R., Tipton, K. D. & Witard, O. C., 28 Jun 2018, In : British Journal of Nutrition. 119, 12, p. 1355-1365 11 p.

    Research output: Contribution to journalArticle

  10. E-pub ahead of print

    Germline variants of BAP1 in the Australian population: Journal of Clinical Oncology

    Walpole, S., Pritchard, A., Palmer, J., Howlie, M., Symmons, J., Hamilton, H., Glasson, W., Warrier, S., Rolfe, O., Stark, A., D'Mellow, M. & Hayward, N., 1 Jun 2018, In : Journal of Clinical Oncology. 36, 15 Suppl, p. e13534-e13534

    Research output: Contribution to journalMeeting abstract

  11. Published

    13 reasons why the brain is susceptible to oxidative stress

    Cobley, J. & Bailey, D., 31 May 2018, In : Redox Biology. 15, p. 490-503 15 p.

    Research output: Contribution to journalReview article

  12. Published

    Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria

    Burleigh, M. C., Liddle, L., Monaghan, C., Muggeridge, D. J., Sculthorpe, N., Butcher, J. P., Henriquez, F. L., Allen, J. D. & Easton, C., 20 May 2018, In : Free Radical Biology & Medicine. 120, p. 80-88 9 p.

    Research output: Contribution to journalArticle

  13. Published

    Effects of hunger state on the brain responses to food cues across the life span

    Full4Health consortium, Charbonnier, L., van Meer, F., Johnstone, A. M., Crabtree, D., Buosi, W., Manios, Y., Androutsos, O., Giannopoulou, A., Viergever, M. A. & Smeets, P. A. M., 1 May 2018, In : Neuroimage. 171, p. 246-255 10 p.

    Research output: Contribution to journalArticle

  14. Published

    Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

    Boyapati, R. K., Dorward, D. A., Tamborska, A., Kalla, R., Ventham, N. T., Doherty, M. K., Whitfield, P. D., Gray, M., Loane, J., Rossi, A. G., Satsangi, J. & Ho, G., 1 May 2018, In : Inflammatory Bowel Diseases. 24, 10, p. 2113-2122 9 p.

    Research output: Contribution to journalArticle

  15. Published

    The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes

    Monaghan, C., McIlvenna, L. C., Liddle, L., Burleigh, M., Weller, R. B., Fernandez, B. O., Feelisch, M., Muggeridge, D. J. & Easton, C., May 2018, In : European Journal of Applied Physiology. 118, 5, p. 1043-1052 10 p.

    Research output: Contribution to journalArticle

  16. Published

    Proteomic identification of potential markers of myosteatosis in human urine

    Husi, H., MacDonald, A., Skipworth, R. J. E., Miller, J., Cronshaw, A., Fearon, K. C. H. & Ross, J. A., 25 Apr 2018, In : Biomedical Reports. 8, p. 557-564 8 p.

    Research output: Contribution to journalArticle

  17. Published

    Urinary diagnostic proteomic markers for dynapenia in cancer patients

    Husi, H., MacDonald, A., Skipworth, R. J. E., Miller, J., Cronshaw, A., Greig, C., Fearon, K. C. H. & Ross, J. A., 25 Apr 2018, In : Biomedical Reports. 8, 6, p. 547-556 10 p.

    Research output: Contribution to journalArticle

  18. Published

    Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers

    Pritchard, A. L., Johansson, P. A., Nathan, V., Howlie, M., Symmons, J., Palmer, J. M. & Hayward, N. K., 11 Apr 2018, In : PLoS ONE. 13, 4, p. e0194098

    Research output: Contribution to journalArticle

  19. Published

    Integrative analysis of Multiple Sclerosis using a systems biology approach

    Cervantes-Gracia, K. & Husi, H., 4 Apr 2018, In : Scientific Reports. 8, p. 1-14 14 p., 5633.

    Research output: Contribution to journalArticle

  20. Published

    Targeting Neoantigens for Personalised Immunotherapy

    Pritchard, A. L., 1 Apr 2018, In : BioDrugs. 32, 2, p. 99-109 11 p.

    Research output: Contribution to journalArticle

  21. E-pub ahead of print

    Acute stress alters the rates of degradation of cardiac muscle proteins

    Geary, B., Magee, K., Cash, P., Husi, H., Young, I. S., Whitfield, P. D. & Doherty, M. K., 22 Mar 2018, In : Journal of Proteomics. 7 p.

    Research output: Contribution to journalArticle

  22. Published

    Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

    Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-haberle, I., Murphy, M. P., Moult, P. R. & Cobley, J. N., 20 Mar 2018, In : Redox Biology. 16, p. 344-351 8 p.

    Research output: Contribution to journalArticle

  23. Published

    Oncogenic IDH1 mutations promote enhanced proline synthesis through pycr1 to support the maintenance of mitochondrial redox homeostasis

    Hollinshead, K. ER., Munford, H., Eales, K. L., Bardella, C., Li, C., Escribano-Gonzalez, C., Thakker, A., Nonnenmacher, Y., Kluckova, K. & Jeeves, M., 20 Mar 2018, In : Cell Reports. 22, 12, p. 3107-3114 8 p.

    Research output: Contribution to journalArticle

  24. Published

    Untargeted Metabolomics Profiling of an 80.5 km Simulated Treadmill Ultramarathon

    Howe, C. C. F., Alshehri, A., Muggeridge, D., Mullen, A. B., Boyd, M., Spendiff, O., Moir, H. J. & Watson, D. G., 13 Feb 2018, In : Metabolites. 8, 1

    Research output: Contribution to journalArticle

  25. Published

    IDH1 mutations drive an oxygen-sparing metabolic phenotype to permit tumour growth (Abstract)

    Hollinshead, K., Munford, M. H., Eales, M. K., Gonzalez, M. C. E., Thakker, A., Cuozzo, M. F., Murren, M. R., Ludwig, C. & Tennant, D., 31 Jan 2018, In : Neuro-Oncology. 20, Suppl 1, p. i4

    Research output: Contribution to journalArticle

  26. Published

    Changes in body posture alter plasma nitrite but not nitrate concentration in humans

    Liddle, L., Monaghan, C., Burleigh, M. C., McIlvenna, L. C., Muggeridge, D. J. & Easton, C., 30 Jan 2018, In : Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 72, p. 59-65 7 p.

    Research output: Contribution to journalArticle

  27. Published

    Proteomics and Metabolomics for AKI Diagnosis

    Marx, D., Metzger, J., Pejchinovski, M., Gil, R. B., Frantzi, M., Latosinska, A., Belczacka, I., Heinzmann, S. S., Husi, H., Zoidakis, J., Klingele, M. & Herget-Rosenthal, S., Jan 2018, In : Seminars in Nephrology. 38, 1, p. 63-87 25 p.

    Research output: Contribution to journalArticle

  28. Published

    Database Creation and Utility

    Krochmal, M., Cisek, K. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 286-300 15 p. (Wiley Series on Mass Spectrometry).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  29. Published

    Knowledge Discovery and Data Mining

    Krochmal, M. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 233-247 15 p. (Wiley Series on Mass Spectrometry).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. Published

    Molecular Model for CKD

    Fernandes, M., Cisek, K. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 327-346 20 p. (Wiley Series on Mass Spectrometry).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  31. 2017
  32. Published

    Intergenic disease-associated regions are abundant in novel transcripts

    Bartonicek, N., Clark, MB., Quek, X. C., Torpy, J. R., Pritchard, A. L., Maag, J. L. V., Gloss, B. S., Crawford, J., Taft, R. J., Hayward, N. K., Montgomery, G. W., Mattick, J. S., Mercer, T. R. & Dinger, M. E., 28 Dec 2017, In : Genome Biology. 18, 16 p.

    Research output: Contribution to journalArticle

  33. E-pub ahead of print

    Novel Vanillin Derivatives: Synthesis, anti-oxidant, DNA and Cellular protection properties

    Scipioni, M., Kay, G., Megson, I. & Kong, P., 2 Dec 2017, In : European Journal of Medicinal Chemistry. p. 745-754 9 p.

    Research output: Contribution to journalArticle

  34. Published

    Germline Variation at CDKN2A and Associations with Nevus Phenotypes among Members of Melanoma Families

    Taylor, N. J., Mitra, N., Goldstein, A. M., Tucker, M. A., Avril, M., Azizi, E., Bergman, W., Bishop, D. T., Bressac-de Paillerets, B., Bruno, W., Calista, D., Cannon-albright, L. A., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Gerdes, A., Ghiorzo, P., Grazziotin, T. C., Hansson, J. & 24 others, Harland, M., Hayward, N. K., Hocevar, M., Höiom, V., Ingvar, C., Landi, M. T., Landman, G., Larre-borges, A., Leachman, S. A., Mann, G. J., Nagore, E., Olsson, H., Palmer, J. M., Perić, B., Pjanova, D., Pritchard, A., Puig, S., Van Der Stoep, N., Wadt, K. A. W., Whitaker, L., Yang, X. R., Newton Bishop, J. A., Gruis, N. A. & Kanetsky, P. A., 1 Dec 2017, In : Journal of Investigative Dermatology. 137, 12, p. 2606-2612 7 p.

    Research output: Contribution to journalArticle

  35. Published

    Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy

    Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H. & Vlahou, A., 9 Nov 2017, In : Scientific Reports. 7, 1, 15160.

    Research output: Contribution to journalArticle

  36. Published

    Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma

    McEvoy, A. C., Calapre, L., Pereira, M. R., Giardina, T., Robinson, C., Khattak, M. A., Meniawy, T. M., Pritchard, A. L., Hayward, N. K., Amanuel, B., Millward, M., Ziman, M. & Gray, E. S., 3 Oct 2017, In : Oncotarget. 8, 45, p. 78890-78900 11 p.

    Research output: Contribution to journalArticle

  37. Published

    MitoNeoD: A Mitochondria-Targeted Superoxide Probe

    Shchepinova, M. M., Cairns, A. G., Prime, T. A., Logan, A., James, A. M., Hall, A. R., Vidoni, S., Arndt, S., Caldwell, S. T., Prag, H. A., Pell, V. R., Krieg, T., Mulvey, J. F., Yadav, P., Cobley, J. N., Bright, T. P., Senn, H. M., Anderson, R. F., Murphy, M. P. & Hartley, R. C., 1 Oct 2017, In : Cell Chemical Biology. 24, 10, p. 1285-1298.e12

    Research output: Contribution to journalArticle

  38. Published

    An examination of objectively-measured sedentary behavior and mental well-being in adults across week days and weekends

    Gibson, A-M., Muggeridge, D. J., Hughes, A. R., Kelly, L. & Kirk, A., 21 Sep 2017, In : PLoS ONE. 12, 9, p. e0185143

    Research output: Contribution to journalArticle

  39. Published
  40. Published

    Exercise redox biochemistry: Conceptual, methodological and technical recommendations

    Cobley, J. N., Close, G. L., Bailey, D. M. & Davison, G. W., Aug 2017, In : Redox Biology. 12, p. 540-548 9 p.

    Research output: Contribution to journalArticle

  41. E-pub ahead of print

    Lipid remodelling and an altered membrane proteome may drive the effects of EPA and DHA treatment on skeletal muscle glucose uptake and protein accretion

    Jeromson, S., Mackenzie, I., Doherty, M. K., Whitfield, P. D., Bell, G., Dick, J., Shaw, A., Rao, F., Ashcroft, S., Philp, A., Galloway, S., Gallagher, I. J. & Hamilton, D. L., 27 Jun 2017, In : American Journal of Physiology - Endocrinology And Metabolism. ajpendo.00438.2015.

    Research output: Contribution to journalArticle

  42. Published

    Novel germline variants in cutaneous and uveal melanoma families

    Hayward, N. K., Pritchard, A., Johansson, P. A., Aoude, L. G., Jonsson, G., Hoiom, V. & Wadt, K., 20 Jun 2017, In : Journal of the European Academy of Dermatology and Venereology. 31, p. 46-46 1 p.

    Research output: Contribution to journalMeeting abstract

  43. E-pub ahead of print

    Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE -/- mouse model of atherosclerosis with alterations in IL10/AMPKα pathway

    Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Ziegler, K., Whitfield, P., Mody, N., Wilson, H. M. & Delibegovic, M., 13 Jun 2017, In : Molecular Metabolism.

    Research output: Contribution to journalArticle

  44. Published

    Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods

    Edmonds, M. J., Geary, B., Doherty, M. K. & Morgan, A., 12 Jun 2017, In : Scientific Reports. 7, 1, 3299.

    Research output: Contribution to journalArticle

  45. Published
  46. Published

    Whole-genome landscapes of major melanoma subtypes

    Hayward, N. K., Wilmott, J. S., Waddell, N., Johansson, P. A., Field, M. A., Nones, K., Patch, A-M., Kakavand, H., Alexandrov, L. B., Burke, H., Jakrot, V., Kazakoff, S., Holmes, O., Leonard, C., Sabarinathan, R., Mularoni, L., Wood, S., Xu, Q., Waddell, N., Tembe, V. & 29 others, Pupo, G. M., De Paoli-Iseppi, R., Vilain, R. E., Shang, P., Lau, L. M. S., Dagg, R. A., Schramm, S-J., Pritchard, A., Dutton-Regester, K., Newell, F., Fitzgerald, A., Shang, C. A., Grimmond, S. M., Pickett, H. A., Yang, J. Y., Stretch, J. R., Behren, A., Kefford, R. F., Hersey, P., Long, G. V., Cebon, J., Shackleton, M., Spillane, A. J., Saw, R. P. M., Lopez-Bigas, N., Pearson, J. V., Thompson, J. F., Scolyer, R. A. & Mann, G. J., 11 May 2017, In : Nature. 545, 7653, p. 175-180 6 p.

    Research output: Contribution to journalArticle

  47. Published

    Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome

    Dorward, D. A., Lucas, C. D., Doherty, M. K., Chapman, G. B., Scholefield, E. J., Conway Morris, A., Felton, J. M., Kipari, T., Humphries, D. C., Robb, C. T., Simpson, A. J., Whitfield, P. D., Haslett, C., Dhaliwal, K. & Rossi, A. G., 3 May 2017, In : Thorax. p. thoraxjnl-2017-210030

    Research output: Contribution to journalArticle

  48. Published

    Beetroot juice versus chard gel: A pharmacokinetic and pharmacodynamic comparison of nitrate bioavailability

    McIlvenna, L. C., Monaghan, C., Liddle, L., Fernandez, B. O., Feelisch, M., Muggeridge, D. J. & Easton, C., 1 Apr 2017, In : Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 64, p. 61-67 7 p.

    Research output: Contribution to journalArticle

  49. Published
  50. Published

    Study of natural IgG antibodies against vascular endothelial growth factor receptor 1 in hepatocellular carcinoma: Anti-VEGFR1 IgG and hepatocellular carcinoma

    Wang Y, Yan Z, Huang Y, Qiu C, Chen X, Hu Y, Meng Q & Wei J., 29 Mar 2017, In : American Journal of Cancer Research. 7, 3, p. 603-609 7 p., AJCR0050989.

    Research output: Contribution to journalArticle

  51. Published

    Mutation load in melanoma is affected by MC1R genotype

    Johansson, P. A., Pritchard, A. L., Patch, A-M., Wilmott, J. S., Pearson, J. V., Waddell, N., Scolyer, R. A., Mann, G. J. & Hayward, N. K., 7 Mar 2017, In : Pigment Cell and Melanoma Research. 30, 2, p. 255-258 4 p.

    Research output: Contribution to journalArticle

  52. Published

    Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

    Morrice, N., Mcilroy, G. D., Tammireddy, S. R., Reekie, J., Shearer, K. D., Doherty, M. K., Delibegovi??, M., Whitfield, P. D. & Mody, N., 3 Mar 2017, In : Scientific Reports. 7, 43782 .

    Research output: Contribution to journalArticle

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