Research Publications

  1. 2018
  2. E-pub ahead of print

    MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells

    Valiño-Rivas, L., Cuarental, L., Agustin, M., Husi, H., Cannata-Ortiz, P., Sanz, A. B., Mischak, H., Ortiz, A. & Sanchez-Niño, M. D., 11 Dec 2018, In : Nephrology, Dialysis, Transplantation. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  3. Published

    The Many Facets of Fabry Disease in the Kidney-Heart Axis

    Fernandes, M. & Husi, H., 15 Nov 2018, In : Journal of Nephrology & Kidney Diseases . 1, 2, p. 1-4 4 p., 120.

    Research output: Contribution to journalArticle

  4. Published

    C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD)

    Fernandes, M., Patel, A. & Husi, H., 12 Nov 2018, In : PLoS ONE. 13, 11, p. 1-28 28 p., e0207371.

    Research output: Contribution to journalArticle

  5. Published

    Tapping all our Talents 2018

    Yellowlees, L., Arnold, P., Bell Burnell, J., Brown, A., Doherty, M. & Colquhoun, A., 12 Nov 2018, Edinburgh: The Royal Society of Edinburgh. 108 p.

    Research output: Book/ReportCommissioned report

  6. E-pub ahead of print

    The glycine lipids of Bacteroides thetaiotaomicron are important for fitness during growth in vivo and in vitro

    Lynch, A., Tammireddy, S. R., Doherty, M. K., Whitfield, P. D. & Clarke, D. J., 26 Oct 2018, In : Applied and Environmental Microbiology.

    Research output: Contribution to journalArticle

  7. E-pub ahead of print

    Identifying neoantigens for use in immunotherapy

    Hutchison, S. & Pritchard, A. L., 24 Aug 2018, In : Mammalian Genome. p. 1-17 17 p.

    Research output: Contribution to journalArticle

  8. Published

    Alteration of circulating natural autoantibodies to CD25-derived peptide antigens and FOXP3 in non-small cell lung cancer

    Zhao H, Zhang X, Han Z, Xie W, Yang W & Wei, J., 29 Jun 2018, In : Scientific Reports. 8, p. 1-8 8 p., 9847 (2018).

    Research output: Contribution to journalArticle

  9. Published

    A bedtime milk snack does not impact RMR, substrate utilisation and appetite the following morning in mildly overweight males

    Lay, A. H. H., Crabtree, D. R., Campbell, T. G., Dreczkowski, G. M., Galloway, S. D. R., Tipton, K. D. & Witard, O. C., 28 Jun 2018, In : British Journal of Nutrition. 119, 12, p. 1355-1365 11 p.

    Research output: Contribution to journalArticle

  10. E-pub ahead of print

    Germline variants of BAP1 in the Australian population: Journal of Clinical Oncology

    Walpole, S., Pritchard, A., Palmer, J., Howlie, M., Symmons, J., Hamilton, H., Glasson, W., Warrier, S., Rolfe, O., Stark, A., D'Mellow, M. & Hayward, N., 1 Jun 2018, In : Journal of Clinical Oncology. 36, 15 Suppl, p. e13534-e13534

    Research output: Contribution to journalMeeting abstract

  11. Published

    13 reasons why the brain is susceptible to oxidative stress

    Cobley, J. & Bailey, D., 31 May 2018, In : Redox Biology. 15, p. 490-503 15 p.

    Research output: Contribution to journalReview article

  12. Published

    Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria

    Burleigh, M. C., Liddle, L., Monaghan, C., Muggeridge, D. J., Sculthorpe, N., Butcher, J. P., Henriquez, F. L., Allen, J. D. & Easton, C., 20 May 2018, In : Free Radical Biology & Medicine. 120, p. 80-88 9 p.

    Research output: Contribution to journalArticle

  13. Published

    Effects of hunger state on the brain responses to food cues across the life span

    Full4Health consortium, Charbonnier, L., van Meer, F., Johnstone, A. M., Crabtree, D., Buosi, W., Manios, Y., Androutsos, O., Giannopoulou, A., Viergever, M. A. & Smeets, P. A. M., 1 May 2018, In : Neuroimage. 171, p. 246-255 10 p.

    Research output: Contribution to journalArticle

  14. Published

    Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

    Boyapati, R. K., Dorward, D. A., Tamborska, A., Kalla, R., Ventham, N. T., Doherty, M. K., Whitfield, P. D., Gray, M., Loane, J., Rossi, A. G., Satsangi, J. & Ho, G., 1 May 2018, In : Inflammatory Bowel Diseases. 24, 10, p. 2113-2122 9 p.

    Research output: Contribution to journalArticle

  15. Published

    The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes

    Monaghan, C., McIlvenna, L. C., Liddle, L., Burleigh, M., Weller, R. B., Fernandez, B. O., Feelisch, M., Muggeridge, D. J. & Easton, C., May 2018, In : European Journal of Applied Physiology. 118, 5, p. 1043-1052 10 p.

    Research output: Contribution to journalArticle

  16. Published

    Proteomic identification of potential markers of myosteatosis in human urine

    Husi, H., MacDonald, A., Skipworth, R. J. E., Miller, J., Cronshaw, A., Fearon, K. C. H. & Ross, J. A., 25 Apr 2018, In : Biomedical Reports. 8, p. 557-564 8 p.

    Research output: Contribution to journalArticle

  17. Published

    Urinary diagnostic proteomic markers for dynapenia in cancer patients

    Husi, H., MacDonald, A., Skipworth, R. J. E., Miller, J., Cronshaw, A., Greig, C., Fearon, K. C. H. & Ross, J. A., 25 Apr 2018, In : Biomedical Reports. 8, 6, p. 547-556 10 p.

    Research output: Contribution to journalArticle

  18. Published

    Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers

    Pritchard, A. L., Johansson, P. A., Nathan, V., Howlie, M., Symmons, J., Palmer, J. M. & Hayward, N. K., 11 Apr 2018, In : PLoS ONE. 13, 4, p. e0194098

    Research output: Contribution to journalArticle

  19. Published

    Integrative analysis of Multiple Sclerosis using a systems biology approach

    Cervantes-Gracia, K. & Husi, H., 4 Apr 2018, In : Scientific Reports. 8, p. 1-14 14 p., 5633.

    Research output: Contribution to journalArticle

  20. Published

    Targeting Neoantigens for Personalised Immunotherapy

    Pritchard, A. L., 1 Apr 2018, In : BioDrugs. 32, 2, p. 99-109 11 p.

    Research output: Contribution to journalArticle

  21. E-pub ahead of print

    Acute stress alters the rates of degradation of cardiac muscle proteins

    Geary, B., Magee, K., Cash, P., Husi, H., Young, I. S., Whitfield, P. D. & Doherty, M. K., 22 Mar 2018, In : Journal of Proteomics. 7 p.

    Research output: Contribution to journalArticle

  22. Published

    Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

    Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-haberle, I., Murphy, M. P., Moult, P. R. & Cobley, J. N., 20 Mar 2018, In : Redox Biology. 16, p. 344-351 8 p.

    Research output: Contribution to journalArticle

  23. Published

    Oncogenic IDH1 mutations promote enhanced proline synthesis through pycr1 to support the maintenance of mitochondrial redox homeostasis

    Hollinshead, K. ER., Munford, H., Eales, K. L., Bardella, C., Li, C., Escribano-Gonzalez, C., Thakker, A., Nonnenmacher, Y., Kluckova, K. & Jeeves, M., 20 Mar 2018, In : Cell Reports. 22, 12, p. 3107-3114 8 p.

    Research output: Contribution to journalArticle

  24. Published

    Untargeted Metabolomics Profiling of an 80.5 km Simulated Treadmill Ultramarathon

    Howe, C. C. F., Alshehri, A., Muggeridge, D., Mullen, A. B., Boyd, M., Spendiff, O., Moir, H. J. & Watson, D. G., 13 Feb 2018, In : Metabolites. 8, 1

    Research output: Contribution to journalArticle

  25. Published

    IDH1 mutations drive an oxygen-sparing metabolic phenotype to permit tumour growth (Abstract)

    Hollinshead, K., Munford, M. H., Eales, M. K., Gonzalez, M. C. E., Thakker, A., Cuozzo, M. F., Murren, M. R., Ludwig, C. & Tennant, D., 31 Jan 2018, In : Neuro-Oncology. 20, Suppl 1, p. i4

    Research output: Contribution to journalArticle

  26. Published

    Changes in body posture alter plasma nitrite but not nitrate concentration in humans

    Liddle, L., Monaghan, C., Burleigh, M. C., McIlvenna, L. C., Muggeridge, D. J. & Easton, C., 30 Jan 2018, In : Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 72, p. 59-65 7 p.

    Research output: Contribution to journalArticle

  27. Published

    Proteomics and Metabolomics for AKI Diagnosis

    Marx, D., Metzger, J., Pejchinovski, M., Gil, R. B., Frantzi, M., Latosinska, A., Belczacka, I., Heinzmann, S. S., Husi, H., Zoidakis, J., Klingele, M. & Herget-Rosenthal, S., Jan 2018, In : Seminars in Nephrology. 38, 1, p. 63-87 25 p.

    Research output: Contribution to journalArticle

  28. Published

    Database Creation and Utility

    Krochmal, M., Cisek, K. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 286-300 15 p. (Wiley Series on Mass Spectrometry).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  29. Published

    Knowledge Discovery and Data Mining

    Krochmal, M. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 233-247 15 p. (Wiley Series on Mass Spectrometry).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. Published

    Molecular Model for CKD

    Fernandes, M., Cisek, K. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 327-346 20 p. (Wiley Series on Mass Spectrometry).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  31. 2017
  32. Published

    Intergenic disease-associated regions are abundant in novel transcripts

    Bartonicek, N., Clark, MB., Quek, X. C., Torpy, J. R., Pritchard, A. L., Maag, J. L. V., Gloss, B. S., Crawford, J., Taft, R. J., Hayward, N. K., Montgomery, G. W., Mattick, J. S., Mercer, T. R. & Dinger, M. E., 28 Dec 2017, In : Genome Biology. 18, 16 p.

    Research output: Contribution to journalArticle

  33. E-pub ahead of print

    Novel Vanillin Derivatives: Synthesis, anti-oxidant, DNA and Cellular protection properties

    Scipioni, M., Kay, G., Megson, I. & Kong, P., 2 Dec 2017, In : European Journal of Medicinal Chemistry. p. 745-754 9 p.

    Research output: Contribution to journalArticle

  34. Published

    Germline Variation at CDKN2A and Associations with Nevus Phenotypes among Members of Melanoma Families

    Taylor, N. J., Mitra, N., Goldstein, A. M., Tucker, M. A., Avril, M., Azizi, E., Bergman, W., Bishop, D. T., Bressac-de Paillerets, B., Bruno, W., Calista, D., Cannon-albright, L. A., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Gerdes, A., Ghiorzo, P., Grazziotin, T. C., Hansson, J. & 24 others, Harland, M., Hayward, N. K., Hocevar, M., Höiom, V., Ingvar, C., Landi, M. T., Landman, G., Larre-borges, A., Leachman, S. A., Mann, G. J., Nagore, E., Olsson, H., Palmer, J. M., Perić, B., Pjanova, D., Pritchard, A., Puig, S., Van Der Stoep, N., Wadt, K. A. W., Whitaker, L., Yang, X. R., Newton Bishop, J. A., Gruis, N. A. & Kanetsky, P. A., 1 Dec 2017, In : Journal of Investigative Dermatology. 137, 12, p. 2606-2612 7 p.

    Research output: Contribution to journalArticle

  35. Published

    Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy

    Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H. & Vlahou, A., 9 Nov 2017, In : Scientific Reports. 7, 1, 15160.

    Research output: Contribution to journalArticle

  36. Published

    Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma

    McEvoy, A. C., Calapre, L., Pereira, M. R., Giardina, T., Robinson, C., Khattak, M. A., Meniawy, T. M., Pritchard, A. L., Hayward, N. K., Amanuel, B., Millward, M., Ziman, M. & Gray, E. S., 3 Oct 2017, In : Oncotarget. 8, 45, p. 78890-78900 11 p.

    Research output: Contribution to journalArticle

  37. Published

    MitoNeoD: A Mitochondria-Targeted Superoxide Probe

    Shchepinova, M. M., Cairns, A. G., Prime, T. A., Logan, A., James, A. M., Hall, A. R., Vidoni, S., Arndt, S., Caldwell, S. T., Prag, H. A., Pell, V. R., Krieg, T., Mulvey, J. F., Yadav, P., Cobley, J. N., Bright, T. P., Senn, H. M., Anderson, R. F., Murphy, M. P. & Hartley, R. C., 1 Oct 2017, In : Cell Chemical Biology. 24, 10, p. 1285-1298.e12

    Research output: Contribution to journalArticle

  38. Published

    An examination of objectively-measured sedentary behavior and mental well-being in adults across week days and weekends

    Gibson, A-M., Muggeridge, D. J., Hughes, A. R., Kelly, L. & Kirk, A., 21 Sep 2017, In : PLoS ONE. 12, 9, p. e0185143

    Research output: Contribution to journalArticle

  39. Published
  40. Published

    Exercise redox biochemistry: Conceptual, methodological and technical recommendations

    Cobley, J. N., Close, G. L., Bailey, D. M. & Davison, G. W., Aug 2017, In : Redox Biology. 12, p. 540-548 9 p.

    Research output: Contribution to journalArticle

  41. E-pub ahead of print

    Lipid remodelling and an altered membrane proteome may drive the effects of EPA and DHA treatment on skeletal muscle glucose uptake and protein accretion

    Jeromson, S., Mackenzie, I., Doherty, M. K., Whitfield, P. D., Bell, G., Dick, J., Shaw, A., Rao, F., Ashcroft, S., Philp, A., Galloway, S., Gallagher, I. J. & Hamilton, D. L., 27 Jun 2017, In : American Journal of Physiology - Endocrinology And Metabolism. ajpendo.00438.2015.

    Research output: Contribution to journalArticle

  42. Published

    Novel germline variants in cutaneous and uveal melanoma families

    Hayward, N. K., Pritchard, A., Johansson, P. A., Aoude, L. G., Jonsson, G., Hoiom, V. & Wadt, K., 20 Jun 2017, In : Journal of the European Academy of Dermatology and Venereology. 31, p. 46-46 1 p.

    Research output: Contribution to journalMeeting abstract

  43. E-pub ahead of print

    Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE -/- mouse model of atherosclerosis with alterations in IL10/AMPKα pathway

    Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Ziegler, K., Whitfield, P., Mody, N., Wilson, H. M. & Delibegovic, M., 13 Jun 2017, In : Molecular Metabolism.

    Research output: Contribution to journalArticle

  44. Published

    Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods

    Edmonds, M. J., Geary, B., Doherty, M. K. & Morgan, A., 12 Jun 2017, In : Scientific Reports. 7, 1, 3299.

    Research output: Contribution to journalArticle

  45. Published
  46. Published

    Whole-genome landscapes of major melanoma subtypes

    Hayward, N. K., Wilmott, J. S., Waddell, N., Johansson, P. A., Field, M. A., Nones, K., Patch, A-M., Kakavand, H., Alexandrov, L. B., Burke, H., Jakrot, V., Kazakoff, S., Holmes, O., Leonard, C., Sabarinathan, R., Mularoni, L., Wood, S., Xu, Q., Waddell, N., Tembe, V. & 29 others, Pupo, G. M., De Paoli-Iseppi, R., Vilain, R. E., Shang, P., Lau, L. M. S., Dagg, R. A., Schramm, S-J., Pritchard, A., Dutton-Regester, K., Newell, F., Fitzgerald, A., Shang, C. A., Grimmond, S. M., Pickett, H. A., Yang, J. Y., Stretch, J. R., Behren, A., Kefford, R. F., Hersey, P., Long, G. V., Cebon, J., Shackleton, M., Spillane, A. J., Saw, R. P. M., Lopez-Bigas, N., Pearson, J. V., Thompson, J. F., Scolyer, R. A. & Mann, G. J., 11 May 2017, In : Nature. 545, 7653, p. 175-180 6 p.

    Research output: Contribution to journalArticle

  47. Published

    Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome

    Dorward, D. A., Lucas, C. D., Doherty, M. K., Chapman, G. B., Scholefield, E. J., Conway Morris, A., Felton, J. M., Kipari, T., Humphries, D. C., Robb, C. T., Simpson, A. J., Whitfield, P. D., Haslett, C., Dhaliwal, K. & Rossi, A. G., 3 May 2017, In : Thorax. p. thoraxjnl-2017-210030

    Research output: Contribution to journalArticle

  48. Published

    Beetroot juice versus chard gel: A pharmacokinetic and pharmacodynamic comparison of nitrate bioavailability

    McIlvenna, L. C., Monaghan, C., Liddle, L., Fernandez, B. O., Feelisch, M., Muggeridge, D. J. & Easton, C., 1 Apr 2017, In : Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 64, p. 61-67 7 p.

    Research output: Contribution to journalArticle

  49. Published
  50. Published

    Study of natural IgG antibodies against vascular endothelial growth factor receptor 1 in hepatocellular carcinoma: Anti-VEGFR1 IgG and hepatocellular carcinoma

    Wang Y, Yan Z, Huang Y, Qiu C, Chen X, Hu Y, Meng Q & Wei J., 29 Mar 2017, In : American Journal of Cancer Research. 7, 3, p. 603-609 7 p., AJCR0050989.

    Research output: Contribution to journalArticle

  51. Published

    Mutation load in melanoma is affected by MC1R genotype

    Johansson, P. A., Pritchard, A. L., Patch, A-M., Wilmott, J. S., Pearson, J. V., Waddell, N., Scolyer, R. A., Mann, G. J. & Hayward, N. K., 7 Mar 2017, In : Pigment Cell and Melanoma Research. 30, 2, p. 255-258 4 p.

    Research output: Contribution to journalArticle

  52. Published

    Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

    Morrice, N., Mcilroy, G. D., Tammireddy, S. R., Reekie, J., Shearer, K. D., Doherty, M. K., Delibegovi??, M., Whitfield, P. D. & Mody, N., 3 Mar 2017, In : Scientific Reports. 7, 43782 .

    Research output: Contribution to journalArticle

  53. Published

    Mitogen-activated protein kinase 14 promotes AKI

    Ortiz, A., Husi, H., Gonzalez-Lafuente, L., Valiño-Rivas, L., Fresno, M., Sanz, A. B., Mullen, W., Albalat, A., Mezzano, S., Vlahou, T., Mischak, H. & Sanchez-Niño, M. D., 1 Mar 2017, In : Journal of the American Society of Nephrology. 28, 3, p. 823-836 14 p.

    Research output: Contribution to journalArticle

  54. Published

    CVD and oxidative stress

    Gracia, K. C., Llanas-Cornejo, D. & Husi, H., 20 Feb 2017, In : Journal of Clinical Medicine. 6, 2

    Research output: Contribution to journalArticle

  55. Published

    Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development

    Popat, R. J., Hakki, S., Thakker, A., Coughlan, A. M., Watson, J., Little, M. A., Spickett, C. M., Lavender, P., Afzali, B. & Kemper, C., 26 Jan 2017, In : JCI insight. 2, 2, p. 1-16 16 p., e87379.

    Research output: Contribution to journalArticle

  56. Published

    Systems biology approach in hypertension research

    Delles, C. & Husi, H., 24 Jan 2017, Hypertension: Methods and Protocols. Touyz, R. M. & Schriffin, E. L. (eds.). New York: Springer, Vol. 1527. p. 69-79 11 p. (Methods in molecular biology).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  57. Published

    Tissue proteomics in vascular disease

    Albalat, A., Mullen, W., Husi, H. & Mischak, H., 24 Jan 2017, Hypertension: Methods and Protocols. Touyz, R. M. & Schiffrin, E. L. (eds.). New York: Springer New York, Vol. 1527. p. 53-60 8 p. (Methods in molecular biology).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  58. Published

    Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD)

    Fernandes, M. & Husi, H., 12 Jan 2017, In : Scientific Reports. 7, 40367.

    Research output: Contribution to journalArticle

  59. Published

    Bioactive polyphenols and cardiovascular disease: chemical antagonists, pharmacological agents or xenobiotics that drive an adaptive response?

    Goszcz, K., Duthie, G. G., Stewart, D., Leslie, S. J. & Megson, I. L., 10 Jan 2017, In : British Journal of Pharmacology.

    Research output: Contribution to journalBook/Film/Article review

  60. Published

    The effects of dietary nitrate supplementation on the adaptations to sprint interval training in previously untrained males

    Muggeridge, D. J., Sculthorpe, N., James, P. E. & Easton, C., Jan 2017, In : Journal of Science and Medicine in Sport. 20, 1, p. 92-97 6 p.

    Research output: Contribution to journalArticle

  61. Published

    Abstract 3717: New therapies for the treatment of BRAF/NRAS wild type melanoma: Cancer Research

    Ranzani, M., Kemper, K., Michaut, M., Krijgsman, O., Iyer, V., Speak, A., Nsengimana, J., Wong, K., Grinkevich, V., Aben, N., Velasco-Herrera, M. D. C., Alsinet, C., Sjoberg, M., Rashid, M., Turner, G., Behan, F., Supper, E., Thompson, N., Bignell, G., Dutton-Regester, K. & 10 others, Pritchard, A., Wong, C., McDermott, U., Hayward, N. K., Yusa, K., Newton-Bishop, J., Wessels, L., Garnett, M., Peeper, D. & Adams, D., 2017, In : Cancer Research. 77, 13 Suppl, p. 3717 1 p.

    Research output: Contribution to journalMeeting abstract

  62. Published

    Abstract LB-031: Deciphering distinct roles of RASA2 in melanomagenesis: Cancer Research

    Arafeh, R., Qutob, N., Emmanuel, R. R., Madore, J., Elkahloun, A., Wilmott, J. S. J. S., Gartner, J. J., Pizio, A. D., Rotkopf, R., Dutton-Regester, K., Hill, V., Pritchard, A., Lin, J. C., Rosenberg, S. A., Khan, J., Ben-Dor, S., Niv, M. Y. M. Y., Ulitsky, I., Mann, G. J., Scolyer, R. A. & 2 others, Hayward, N. K. & Samuels, Y., 2017, In : Cancer Research. 77, 13 Suppl, p. LB-031-LB-031

    Research output: Contribution to journalMeeting abstract

  63. Published

    Expert Database for Outstanding Women in Academia

    Doherty, M., 2017

    Research output: Other contribution

  64. 2016
  65. Published

    Integrative systems biology investigation of Fabry disease

    Fernandes, M. & Husi, H., 1 Nov 2016, In : Diseases. 4, 4

    Research output: Contribution to journalArticle

  66. Published

    Objectively Measured Sedentary Time in Children and Their Parents

    Hughes, A. R., Muggeridge, D. J., Gibson, A-M., Johnstone, A. & Kirk, A., 30 Sep 2016, In : AIMS Public Health. 3, 4, p. 823-836 14 p.

    Research output: Contribution to journalArticle

  67. Published

    Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma

    Chaudhuri, R., McSharry, C., Heaney, L. G., Niven, R., Brightling, C. E., Menzies-Gow, A. N., Bucknall, C., Mansur, A. H., Lee, W., Shepherd, M., Spears, M., Cowan, D. C., Husi, H. & Thomson, N. C., 1 Sep 2016, In : Respiratory Medicine. 118, p. 46-52 7 p.

    Research output: Contribution to journalArticle

  68. Published

    PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease

    Krochmal, M., Fernandes, M., Filip, S., Pontillo, C., Husi, H., Zoidakis, J., Mischak, H., Vlahou, A. & Jankowski, J., 1 Sep 2016, In : Database.

    Research output: Contribution to journalArticle

  69. Published

    Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson Disease

    Magalhaes, J., Gegg, M. E., Migdalska-richards, A., Doherty, M. K., Whitfield, P. D. & Schapira, A. H. V., 15 Aug 2016, In : Human Molecular Genetics.

    Research output: Contribution to journalArticle

  70. Published

    Urinary peptide analysis differentiates pancreatic cancer from chronic pancreatitis

    Schönemeier, B., Metzger, J., Klein, J., Husi, H., Bremer, B., Armbrecht, N., Dakna, M., Schanstra, J. P., Rosendahl, J., Wiegand, J., Jäger, M., Mullen, W., Breuil, B., Plentz, R. R., Lichtinghagen, R., Brand, K., Kühnel, F., Mischak, H., Manns, M. P. & Lankisch, T. O., 1 Aug 2016, In : Pancreas. 45, 7, p. 1018-1026 9 p.

    Research output: Contribution to journalArticle

  71. Published

    Patterns of Sedentary Behaviour in Female Office Workers

    Kirk, A., Gibson, A-M., Laverty, K., Muggeridge, D., Kelly, L. & Hughes, A., 24 Jul 2016, In : AIMS Public Health. 3, 3, p. 423-431 9 p.

    Research output: Contribution to journalArticle

  72. Published

    Development of a MALDI MS-based platform for early detection of acute kidney injury

    Carrick, E., Vanmassenhove, J., Glorieux, G., Metzger, J., Dakna, M., Pejchinovski, M., Jankowski, V., Mansoorian, B., Husi, H., Mullen, W., Mischak, H., Vanholder, R. & Biesen, W. V., 1 Jul 2016, In : Proteomics Clinical Applications. 10, 7, p. 732-742 11 p.

    Research output: Contribution to journalArticle

  73. Published

    Identification of new therapies for the treatment of BRAF/NRAS wild-type melanomas by functional screening approaches

    Ranzani, M., Michaut, M., Alsinet, C., Grinkevich, V., Wong, K., Iyer, V., Aben, N., Velasco-Herrera, M. D. C., Sjoberg, M., Rashid, M., Bignell, G., Dutton-Regester, K., Pritchard, A., Vis, D., Turner, G., McDermott, U., Hayward, N. K., Yusa, K., Wessels, L., Garnett, M. & 1 others, Adams, D., Jul 2016, In : Cancer Research. 76, 14, pp 4783.

    Research output: Contribution to journalArticle

  74. Published

    Omics databases on kidney disease: where they can be found and how to benefit from them

    Papadopoulos, T., Krochmal, M., Cisek, K., Fernandes, M., Husi, H., Stevens, R., Bascands, J-L., Schanstra, J. P. & Klein, J., 1 Jun 2016, In : Clinical Kidney Journal. 9, 3, p. 343-352 10 p.

    Research output: Contribution to journalArticle

  75. Published

    Neuronal human BACE1 knockin induces systemic diabetes in mice

    Pluci??ska, K., Dekeryte, R., Koss, D., Shearer, K., Mody, N., Whitfield, P. D., Doherty, M. K., Mingarelli, M., Welch, A., Riedel, G., Delibegovic, M., Platt, B. & Whitfield, P., 2 May 2016, In : Diabetologia.

    Research output: Contribution to journalArticle

  76. Published

    Proteomic identification of potential cancer markers in human urine using subtractive analysis

    Husi, H., Skipworth, R. J. E., Cronshaw, A., Fearon, K. C. H. & Ross, J. A., 1 May 2016, In : International Journal of Oncology. 48, 5, p. 1921-1932 12 p.

    Research output: Contribution to journalArticle

  77. Published

    Lipids and cardiovascular disease: where does dietary intervention sit alongside statin therapy?

    Megson, I., Zabetakis, I. & Whitfield, P. D., 18 Apr 2016, In : Food Funct..

    Research output: Contribution to journalArticle

  78. Published

    Age- and Activity-Related Differences in the Abundance of Myosin Essential and Regulatory Light Chains in Human Muscle

    Cobley, J., Ab. Malik, Z., Morton, J., Close, G., Edwards, B. & Burniston, J., 8 Apr 2016, In : Proteomes. 4, 2, p. 15

    Research output: Contribution to journalArticle

  79. Published

    Determining synthesis rates of individual proteins in zebrafish (Danio rerio) with low levels of a stable isotope labelled amino acid

    Geary, B., Magee, K., Cash, P., Young, I. S., Doherty, M. K. & Whitfield, P., 5 Apr 2016, In : Proteomics. 16, 9, p. 1398–1406 8 p.

    Research output: Contribution to journalArticle

  80. Published

    Comparing Simplification Strategies for the Skeletal Muscle Proteome

    Geary, B., Young, I., Cash, P., Doherty, M. & Whitfield, P., 2 Mar 2016, In : Proteomes. 4, 1, p. 10

    Research output: Contribution to journalArticle

  81. Published

    Proteomics for rejection diagnosis in renal transplant patients: where are we now?

    Gwinner, W., Metzger, J., Husi, H. & Marx, D., 1 Mar 2016, In : World Journal of Transplantation. 6, 1, p. 28-41 14 p.

    Research output: Contribution to journalArticle

  82. Published

    Whole-Body Vibration Training and Its Application to Age-Related Performance Decrements: An Exploratory Analysis

    Hawkey, A., Griffiths, K., Babraj, J. & Cobley, J. N., 1 Feb 2016, In : Journal of Strength and Conditioning Research. 30, 2, p. 555-560 6 p.

    Research output: Contribution to journalArticle

  83. Published

    The acute (immediate) effects of reflexology on arterial compliance in healthy volunteers: A randomised study

    Rollinson, K., Jones, J., Scott, N., Megson, I. L. & Leslie, S. J., Feb 2016, In : Complementary therapies in clinical practice. 22, p. 16-20 5 p.

    Research output: Contribution to journalArticle

  84. Published

    Tuning the Nitric Oxide Release from CPO-27 MOFs

    Cattaneo, D., Warrender, S. J., Duncan, M. J., Kelsall, C. J., Doherty, M. K., Whitfield, P., Megson, I. & Morris, R., 26 Jan 2016, In : RSC Adv.. 17, 6, p. 14059-14067 8 p.

    Research output: Contribution to journalArticle

  85. Published
  86. Published

    Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue

    Mcilroy, G. D., Tammireddy, S. R., Maskrey, B. H., Grant, L., Doherty, M. K., Whitfield, P., Watson, D. G., Delibegović, M. & Mody, N., 15 Jan 2016, In : Biochemical Pharmacology. 100, p. 86-97 11 p.

    Research output: Contribution to journalArticle

  87. Published

    Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study

    Metzger, J., Mullen, W., Husi, H., Stalmach, A., Herget-Rosenthal, S., Groesdonk, H., Mischak, H. & Klingele, M., 2016, In : Critical Care. 20

    Research output: Contribution to journalArticle

  88. 2015
  89. Published

    Anti-p16 autoantibodies may be a useful biomarker for early diagnosis of esophageal cancer.

    Jin Y, Guan S, Liu L, Sun S, Lee KH & Wei J., Dec 2015, In : Asia-Pacific Journal of Clinical Oncology. 11, 4, p. e37-e41 5 p.

    Research output: Contribution to journalArticle

  90. Published

    Lack of genetic association of the TGM2 gene with schizophrenia in a Chinese population

    Wang J, Liu Y, Wang Z, Du W, Hui L, Zhao X, Zhao X, Zhang X & Wei J., Dec 2015, In : Psychiatric Genetics. 25, 6, p. 259-262 4 p.

    Research output: Contribution to journalArticle

  91. Published

    POLE mutations in families predisposed to cutaneous melanoma

    Aoude, L. G., Heitzer, E., Johansson, P. A., Gartside, M., Wadt, K., Pritchard, A. L., Palmer, J. M., Symmons, J., Gerdes, A-M., Montgomery, G. W., Martin, N. G., Tomlinson, I., Kearsey, S. & Hayward, N. K., Dec 2015, In : Familial Cancer. 14, 4, p. 621-628 8 p.

    Research output: Contribution to journalArticle

  92. Published

    Recurrent inactivating RASA2 mutations in melanoma

    Arafeh, R., Qutob, N., Emmanuel, R., Keren-Paz, A., Madore, J., Elkahloun, A., Wilmott, J. S., Gartner, J. J., Di Pizio, A., Winograd-Katz, S., Sindiri, S., Rotkopf, R., Dutton-Regester, K., Johansson, P. A., Pritchard, A. L., Waddell, N., Hill, V. K., Lin, J. C., Hevroni, Y., Rosenberg, S. A. & 8 others, Khan, J., Ben-Dor, S., Niv, M. Y., Ulitsky, I., Mann, G. J., Scolyer, R. A., Hayward, N. K. & Samuels, Y., Dec 2015, In : Nature Genetics. 47, 12, p. 1408-1410 3 p.

    Research output: Contribution to journalArticle

  93. Published

    New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

    Glorieux, G., Mullen, W., Duranton, F., Filip, S., Gayrard, N., Husi, H., Schepers, E., Neirynck, N., Schanstra, J. P., Jankowski, J., Mischak, H., Argilés, À., Vanholder, R., Vlahou, A. & Klein, J., 1 Nov 2015, In : Nephrology Dialysis Transplantation. 30, 11, p. 1842-1852 11 p.

    Research output: Contribution to journalArticle

  94. Published

    Exome Sequencing to Predict Neoantigens in Melanoma

    Pritchard, A. L., Burel, J. G., Neller, M. A., Hayward, N. K., Lopez, J. A., Fatho, M., Lennerz, V., Woelfel, T. & Schmidt, C. W., Sep 2015, In : Cancer Immunology Research. 3, 9, p. 992-998 7 p.

    Research output: Contribution to journalArticle

  95. E-pub ahead of print
  96. Published

    Acute whole body UVA irradiation combined with nitrate ingestion enhances time trial performance in trained cyclists

    Muggeridge, D. J., Sculthorpe, N., Grace, F. M., Willis, G., Thornhill, L., Weller, R. B., James, P. E. & Easton, C., 1 Aug 2015, In : Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 48, p. 3-9 7 p.

    Research output: Contribution to journalArticle

  97. Published

    Diagnosis and prediction of CKD progression by assessment of urinary peptides

    Schanstra, J. P., Zurbig, P., Alkhalaf, A., Argiles, A., Bakker, S. J. L., Beige, J., Bilo, H. J. G., Chatzikyrkou, C., Dakna, M., Dawson, J., Delles, C., Haller, H., Haubitz, M., Husi, H., Jankowski, J., Jerums, G., Kleefstra, N., Kuznetsova, T., Maahs, D. M., Menne, J. & 14 others, Mullen, W., Ortiz, A., Persson, F., Rossing, P., Ruggenenti, P., Rychlik, I., Serra, A. L., Siwy, J., Snell-Bergeon, J., Spasovski, G., Staessen, J. A., Vlahou, A., Mischak, H. & Vanholder, R., 1 Aug 2015, In : Journal of the American Society of Nephrology. 26, 8, p. 1999-2010 12 p.

    Research output: Contribution to journalArticle

  98. Published

    Antioxidants in cardiovascular therapy: panacea or false hope?

    Goszcz, K., Deakin, S., Duthie, G., Stewart, D., Leslie, S. J. & Megson, I., 6 Jul 2015, In : Frontiers in Cardiovascular Medicine. 2, 29, p. 1-22 22 p., 29.

    Research output: Contribution to journalArticle

  99. Published

    Molecular determinants of acute kidney injury

    Husi, H. & Human, C., 1 Jul 2015, In : Journal of Injury and Violence Research. 7, 2, p. 75-86 12 p.

    Research output: Contribution to journalArticle

  100. Published

    Programmed cell death 6 interacting protein (PDCD6IP) and Rabenosyn-5 (ZFYVE20) are potential urinary biomarkers for upper gastrointestinal cancer

    Husi, H., Skipworth, R. J. E., Cronshaw, A., Stephens, N. A., Wackerhage, H., Greig, C., Fearon, K. C. H. & Ross, J. A., 1 Jun 2015, In : Proteomics Clinical Applications. 9, 5-6, p. 586-596 11 p.

    Research output: Contribution to journalArticle

  101. Published

    Exploration of peptides bound to MHC class I molecules in melanoma

    Pritchard, A. L., Hastie, M. L., Neller, M., Gorman, J. J., Schmidt, C. W. & Hayward, N. K., May 2015, In : Pigment Cell and Melanoma Research. 28, 3, p. 281-294 14 p.

    Research output: Contribution to journalArticle

  102. Published
  103. Published

    A study of IgG antibodies to the ApoB protein in non-ST segment elevation acute coronary syndrome

    Zhang, X., Yu, B., Jin, Y., Lei, M., Zhang, X., Duan, Z., Lin, Y., Megson, I. L. & Wei, J., 2 Apr 2015, In : Scandinavian Cardiovascular Journal : SCJ. p. 1-6 6 p.

    Research output: Contribution to journalArticle

  104. Published

    Habitual myofibrillar protein synthesis is normal in patients with upper GI cancer cachexia

    MacDonald, A. J., Johns, N., Stephens, N. A., Greig, C. A., Ross, J. A., Small, A. C., Husi, H., Fearon, K. C. H. & Preston, T., 1 Apr 2015, In : Clinical Cancer Research. 21, 7, p. 1734-1740 7 p.

    Research output: Contribution to journalArticle

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