Tuning the Nitric Oxide Release from CPO-27 MOFs

Damiano Cattaneo; Stewart J Warrender; Morven J. Duncan; Christopher J Kelsall; Mary K Doherty; Phillip Whitfield; Ian Megson; Russell Morris

doi:10.1039/C5RA24023A

Tuning the Nitric Oxide Release from CPO-27 MOFs

Damiano Cattaneo
, Stewart J Warrender
, Morven J. Duncan
, Christopher J Kelsall
, Mary K Doherty
, Phillip Whitfield
, Ian Megson
, Russell Morris

Résultats de recherche: Article › Revue par des pairs

62 Citations (Scopus)

266 Téléchargements (Pure)

Résumé

Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

langue originale	English
Pages (de - à)	14059-14067
Nombre de pages	8
journal	RSC Adv.
Volume	17
Numéro de publication	6
Date de mise en ligne précoce	26 janv. 2016
Les DOIs	https://doi.org/10.1039/C5RA24023A
état	Published - 26 janv. 2016

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10.1039/C5RA24023ALicense: CC BY

Cattaneo_et_al_Tuning_the_Nitric_Oxide_Release_from_CPO_27_MOFS
© 2017 The Authors. Published by the Royal Society of Chemistry
Submitted manuscript, 2,54 MBLicense: CC BY
Tuning the nitric oxide release from CPO-27 MOFs
© 2017 The Authors. Published by the Royal Society of Chemistry
Final published version, 2,62 MBLicense: CC BY

http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C5RA24023ALicense: CC BY

Contient cette citation

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abstract = "Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications",

author = "Damiano Cattaneo and Warrender, \{Stewart J\} and Duncan, \{Morven J.\} and Kelsall, \{Christopher J\} and Doherty, \{Mary K\} and Phillip Whitfield and Ian Megson and Russell Morris",

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AU - Cattaneo, Damiano

AU - Warrender, Stewart J

AU - Duncan, Morven J.

AU - Kelsall, Christopher J

AU - Doherty, Mary K

AU - Whitfield, Phillip

AU - Megson, Ian

AU - Morris, Russell

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AB - Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

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DO - 10.1039/C5RA24023A

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JO - RSC Adv.

JF - RSC Adv.

IS - 6

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Tuning the Nitric Oxide Release from CPO-27 MOFs

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