No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample

Heyao Li; Haiying Zhang; Libo Liu; Guizhi Ju; Shunzi Jin; Lin Ye; Xuan Zhang; Jun Wei

doi:10.1016/j.psychres.2008.11.004

No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample

Heyao Li
, Haiying Zhang
, Libo Liu
, Guizhi Ju
, Shunzi Jin
, Lin Ye
, Xuan Zhang
, Jun Wei

Résultats de recherche: Article › Revue par des pairs

2 Citations (Scopus)

Résumé

The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.

langue originale	English
Pages (de - à)	176-7
Nombre de pages	2
journal	Psychiatry Research
Volume	169
Numéro de publication	2
Les DOIs	https://doi.org/10.1016/j.psychres.2008.11.004
état	Published - 30 sept. 2009

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10.1016/j.psychres.2008.11.004

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title = "No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample",

abstract = "The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.",

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AU - Li, Heyao

AU - Zhang, Haiying

AU - Liu, Libo

AU - Ju, Guizhi

AU - Jin, Shunzi

AU - Ye, Lin

AU - Zhang, Xuan

AU - Wei, Jun

PY - 2009/9/30

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N2 - The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.

AB - The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.

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KW - Asian Continental Ancestry Group

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Female

KW - Gene Frequency

KW - Genetic Predisposition to Disease

KW - Genotype

KW - Humans

KW - Male

KW - Middle Aged

KW - Phosphatidylethanolamine N-Methyltransferase

KW - Polymorphism, Single Nucleotide

KW - Schizophrenia

KW - Young Adult

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DO - 10.1016/j.psychres.2008.11.004

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EP - 177

JO - Psychiatry Research

JF - Psychiatry Research

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ER -

No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample

Résumé

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