N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

A T Treweeke; T J Winterburn; I Mackenzie; F Barrett; C Barr; G F Rushworth; I Dransfield; S M Macrury; I L Megson

doi:10.1007/s00125-012-2685-z

N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

A T Treweeke
, T J Winterburn
, I Mackenzie
, F Barrett
, C Barr
, G F Rushworth
, I Dransfield
, S M Macrury
, I L Megson

Résultats de recherche: Article › Revue par des pairs

42 Citations (Scopus)

Résumé

The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

langue originale	English
Pages (de - à)	2920-8
Nombre de pages	9
journal	Diabetologia
Volume	55
Numéro de publication	11
Les DOIs	https://doi.org/10.1007/s00125-012-2685-z
état	Published - 2012

SDG des Nations Unies

Ce résultat contribue à ou aux Objectifs de développement durable suivants

Good health and well being

Accès au document

10.1007/s00125-012-2685-z

Contient cette citation

Treweeke, A. T., Winterburn, T. J., Mackenzie, I., Barrett, F., Barr, C., Rushworth, G. F., Dransfield, I., Macrury, S. M., & Megson, I. L. (2012). N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial. Diabetologia, 55(11), 2920-8. https://doi.org/10.1007/s00125-012-2685-z

@article{ddafc3fab0b740d18d10a6d361ff01e4,

title = "N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial",

abstract = "The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.",

author = "Treweeke, \{A T\} and Winterburn, \{T J\} and I Mackenzie and F Barrett and C Barr and Rushworth, \{G F\} and I Dransfield and Macrury, \{S M\} and Megson, \{I L\}",

year = "2012",

doi = "10.1007/s00125-012-2685-z",

language = "English",

volume = "55",

pages = "2920--8",

journal = "Diabetologia",

issn = "1432-0428",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "11",

}

Treweeke, AT, Winterburn, TJ, Mackenzie, I, Barrett, F, Barr, C, Rushworth, GF, Dransfield, I, Macrury, SM & Megson, IL 2012, 'N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial', Diabetologia, VOL. 55, Numéro 11, p. 2920-8. https://doi.org/10.1007/s00125-012-2685-z

TY - JOUR

T1 - N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione

T2 - a randomised controlled trial

AU - Treweeke, A T

AU - Winterburn, T J

AU - Mackenzie, I

AU - Barrett, F

AU - Barr, C

AU - Rushworth, G F

AU - Dransfield, I

AU - Macrury, S M

AU - Megson, I L

PY - 2012

Y1 - 2012

N2 - The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

AB - The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

U2 - 10.1007/s00125-012-2685-z

DO - 10.1007/s00125-012-2685-z

M3 - Article

C2 - 22935960

SN - 1432-0428

VL - 55

SP - 2920

EP - 2928

JO - Diabetologia

JF - Diabetologia

IS - 11

ER -

N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

Résumé

SDG des Nations Unies

Accès au document

Empreinte digitale

Contient cette citation