Effect of seven anti-tuberculosis treatment regimens on sputum microbiome:: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

Emmanuel Musisi; Adam Wyness; Wilber Sabiiti

doi:10.1016/S2666-5247(23)00191-X

Effect of seven anti-tuberculosis treatment regimens on sputum microbiome: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

, Emmanuel Musisi
, Adam Wyness
, Wilber Sabiiti

SAMS UHI

Résultats de recherche: Article › Revue par des pairs

11 Citations (Scopus)

Résumé

Respiratory tract microbiota has been described as the gatekeeper for respiratory health. We aimed to assess the impact of standard-of-care and experimental anti-tuberculosis treatment regimens on the respiratory microbiome and implications for treatment outcomes.

langue originale	English
Pages (de - à)	e913-e922
Nombre de pages	10
journal	The Lancet Microbe
Volume	4
Numéro de publication	11
Les DOIs	https://doi.org/10.1016/S2666-5247(23)00191-X
état	Published - 1 nov. 2023

SDG des Nations Unies

Ce résultat contribue à ou aux Objectifs de développement durable suivants

Good health and well being

Accès au document

10.1016/S2666-5247(23)00191-XLicense: CC BY

https://linkinghub.elsevier.com/retrieve/pii/S266652472300191X

Contient cette citation

@article{167be538bd094744b6779b6ce3843aaf,

title = "Effect of seven anti-tuberculosis treatment regimens on sputum microbiome:: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials",

abstract = "Respiratory tract microbiota has been described as the gatekeeper for respiratory health. We aimed to assess the impact of standard-of-care and experimental anti-tuberculosis treatment regimens on the respiratory microbiome and implications for treatment outcomes.",

author = "Emmanuel Musisi and Adam Wyness and Sahar Eldirdiri and Evelin Dombay and Bariki Mtafya and Ntinginya, \{Nyanda e\} and Norbert Heinrich and Kibiki, \{Gibson s\} and Michael Hoelscher and Martin Boeree and Rob Aarnoutse and Gillespie, \{Stephen h\} and Wilber Sabiiti and Emmanuel Musisi and Bariki Mtafya and Ntinginya, \{Nyanda e.\} and Norbert Heinrich and Kibiki, \{Gibson s.\} and Michael Hoelscher and Martin Boeree and Stephen Gillespie and Wilber Sabiiti and Derek Sloan and Larissa Hoffmann and Ivan Nore{\~n}a and Wandini Lutchmun and Julia Dreisbach and Demel,, \{Petra gross\} and Andrea Kelly and Brake, \{Lindsey te\} and Elin Svensson and Rob Aarnoutse and Isobella Honeyborne and Wildner, \{Leticia muraro\} and Robert Hunt and Mchugh, \{Timothy d.\} and Nunn, \{Andrew j\} and Phillips, \{Patrick p.j.\} and Xue Gong and Rodney Dawson and Kim Narunsky and Andreas Diacon and \{De jager\}, Veronique and Sven Friedrich and Ian Sanne and Mohammed Rassool and Chacha Mangu and Christina Manyama and Issa Sabi and Minja, \{Lilian t.\}",

note = "Copyright {\textcopyright} 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license No accepted date specified.",

year = "2023",

month = nov,

day = "1",

doi = "10.1016/S2666-5247(23)00191-X",

language = "English",

volume = "4",

pages = "e913--e922",

number = "11",

}

TY - JOUR

T1 - Effect of seven anti-tuberculosis treatment regimens on sputum microbiome:

T2 - a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

AU - Musisi, Emmanuel

AU - Wyness, Adam

AU - Eldirdiri, Sahar

AU - Dombay, Evelin

AU - Mtafya, Bariki

AU - Ntinginya, Nyanda e

AU - Heinrich, Norbert

AU - Kibiki, Gibson s

AU - Hoelscher, Michael

AU - Boeree, Martin

AU - Aarnoutse, Rob

AU - Gillespie, Stephen h

AU - Sabiiti, Wilber

AU - Musisi, Emmanuel

AU - Mtafya, Bariki

AU - Ntinginya, Nyanda e.

AU - Heinrich, Norbert

AU - Kibiki, Gibson s.

AU - Hoelscher, Michael

AU - Boeree, Martin

AU - Gillespie, Stephen

AU - Sabiiti, Wilber

AU - Sloan, Derek

AU - Hoffmann, Larissa

AU - Noreña, Ivan

AU - Lutchmun, Wandini

AU - Dreisbach, Julia

AU - Demel,, Petra gross

AU - Kelly, Andrea

AU - Brake, Lindsey te

AU - Svensson, Elin

AU - Aarnoutse, Rob

AU - Honeyborne, Isobella

AU - Wildner, Leticia muraro

AU - Hunt, Robert

AU - Mchugh, Timothy d.

AU - Nunn, Andrew j

AU - Phillips, Patrick p.j.

AU - Gong, Xue

AU - Dawson, Rodney

AU - Narunsky, Kim

AU - Diacon, Andreas

AU - De jager, Veronique

AU - Friedrich, Sven

AU - Sanne, Ian

AU - Rassool, Mohammed

AU - Mangu, Chacha

AU - Manyama, Christina

AU - Sabi, Issa

AU - Minja, Lilian t.

PY - 2023/11/1

Y1 - 2023/11/1

N2 - Respiratory tract microbiota has been described as the gatekeeper for respiratory health. We aimed to assess the impact of standard-of-care and experimental anti-tuberculosis treatment regimens on the respiratory microbiome and implications for treatment outcomes.

AB - Respiratory tract microbiota has been described as the gatekeeper for respiratory health. We aimed to assess the impact of standard-of-care and experimental anti-tuberculosis treatment regimens on the respiratory microbiome and implications for treatment outcomes.

U2 - 10.1016/S2666-5247(23)00191-X

DO - 10.1016/S2666-5247(23)00191-X

M3 - Article

SN - 2666-5247

VL - 4

SP - e913-e922

JO - The Lancet Microbe

JF - The Lancet Microbe

IS - 11

ER -

Effect of seven anti-tuberculosis treatment regimens on sputum microbiome: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

Résumé

SDG des Nations Unies

Accès au document

Empreinte digitale

Contient cette citation