Clearance of dying cells and autoimmunity

Sylwia Michlewska; Aisleen McColl; Adriano G Rossi; Ian L Megson; Ian Dransfield

doi:10.1080/08916930701357208

Clearance of dying cells and autoimmunity

Sylwia Michlewska
, Aisleen McColl
, Adriano G Rossi
, Ian L Megson
, Ian Dransfield

Résultats de recherche: Article › Revue par des pairs

43 Citations (Scopus)

Résumé

Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.

langue originale	English
Pages (de - à)	267-73
Nombre de pages	7
journal	Autoimmunity
Volume	40
Numéro de publication	4
Les DOIs	https://doi.org/10.1080/08916930701357208
état	Published - 2007

SDG des Nations Unies

Ce résultat contribue à ou aux Objectifs de développement durable suivants

Good health and well being

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10.1080/08916930701357208

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title = "Clearance of dying cells and autoimmunity",

abstract = "Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.",

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T1 - Clearance of dying cells and autoimmunity

AU - Michlewska, Sylwia

AU - McColl, Aisleen

AU - Rossi, Adriano G

AU - Megson, Ian L

AU - Dransfield, Ian

PY - 2007

Y1 - 2007

N2 - Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.

AB - Phagocytic clearance of apoptotic cells is an important physiologic homeostatic mechanism that is associated with non-inflammatory or anti-inflammatory sequalae. Disruption of the process of apoptotic cell clearance may contribute to development of a number of inflammatory and autoimmune diseases. In this review, we summarize the molecular pathways that have been suggested to account for phagocytic clearance of apoptotic cells. We discuss potential mechanisms for regulation of phagocytosis and the implications for development of autoimmunity.

U2 - 10.1080/08916930701357208

DO - 10.1080/08916930701357208

M3 - Article

C2 - 17516208

SN - 0891-6934

VL - 40

SP - 267

EP - 273

JO - Autoimmunity

JF - Autoimmunity

IS - 4

ER -

Clearance of dying cells and autoimmunity

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SDG des Nations Unies

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