A new approach for creating double-stranded DNA biosensors

Sergey G. Skuridin; Yuri M. Yevdokimov; Vladimir S. Efimov; Jennifer M. Hall; Anthony P.f. Turner

doi:10.1016/0956-5663(96)89439-5

A new approach for creating double-stranded DNA biosensors

Sergey G. Skuridin
, Yuri M. Yevdokimov
, Vladimir S. Efimov
, Jennifer M. Hall
, Anthony P.f. Turner

Centre for Rural Health Sciences

Résultats de recherche: Article › Revue par des pairs

28 Citations (Scopus)

Résumé

The principle of ‘sandwich’-type biosensors based on liquid-crystalline dispersions formed from [DNA-polycation] complexes is outlined. These biosensors will find application in the determination of a range of compounds and physical factors that affect the ability of a given polycationic molecule to maintain intermolecular crosslinks between neighbouring DNA molecules. In the case of liquid-crystalline dispersions formed from [DNA-protamine] complexes, the lowest concentration of hydrolytic enzyme (trypsin) detectable was ∼ 10−14M.

langue originale	English
Pages (de - à)	903-911
journal	Biosensors and Bioelectronics
Volume	11
Numéro de publication	9
Les DOIs	https://doi.org/10.1016/0956-5663(96)89439-5
état	Published - 1 janv. 1996

Accès au document

10.1016/0956-5663(96)89439-5

http://linkinghub.elsevier.com/retrieve/pii/0956566396894395

Contient cette citation

@article{31ca122fb43d4d48ba58d1103c076f1d,

title = "A new approach for creating double-stranded DNA biosensors",

abstract = "The principle of {\textquoteleft}sandwich{\textquoteright}-type biosensors based on liquid-crystalline dispersions formed from [DNA-polycation] complexes is outlined. These biosensors will find application in the determination of a range of compounds and physical factors that affect the ability of a given polycationic molecule to maintain intermolecular crosslinks between neighbouring DNA molecules. In the case of liquid-crystalline dispersions formed from [DNA-protamine] complexes, the lowest concentration of hydrolytic enzyme (trypsin) detectable was ∼ 10−14M.",

author = "Skuridin, \{Sergey G.\} and Yevdokimov, \{Yuri M.\} and Efimov, \{Vladimir S.\} and Hall, \{Jennifer M.\} and Turner, \{Anthony P.f.\}",

year = "1996",

month = jan,

day = "1",

doi = "10.1016/0956-5663(96)89439-5",

language = "English",

volume = "11",

pages = "903--911",

journal = "Biosensors and Bioelectronics",

issn = "0956-5663",

publisher = "Elsevier Ltd",

number = "9",

}

TY - JOUR

T1 - A new approach for creating double-stranded DNA biosensors

AU - Skuridin, Sergey G.

AU - Yevdokimov, Yuri M.

AU - Efimov, Vladimir S.

AU - Hall, Jennifer M.

AU - Turner, Anthony P.f.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - The principle of ‘sandwich’-type biosensors based on liquid-crystalline dispersions formed from [DNA-polycation] complexes is outlined. These biosensors will find application in the determination of a range of compounds and physical factors that affect the ability of a given polycationic molecule to maintain intermolecular crosslinks between neighbouring DNA molecules. In the case of liquid-crystalline dispersions formed from [DNA-protamine] complexes, the lowest concentration of hydrolytic enzyme (trypsin) detectable was ∼ 10−14M.

AB - The principle of ‘sandwich’-type biosensors based on liquid-crystalline dispersions formed from [DNA-polycation] complexes is outlined. These biosensors will find application in the determination of a range of compounds and physical factors that affect the ability of a given polycationic molecule to maintain intermolecular crosslinks between neighbouring DNA molecules. In the case of liquid-crystalline dispersions formed from [DNA-protamine] complexes, the lowest concentration of hydrolytic enzyme (trypsin) detectable was ∼ 10−14M.

U2 - 10.1016/0956-5663(96)89439-5

DO - 10.1016/0956-5663(96)89439-5

M3 - Article

SN - 0956-5663

VL - 11

SP - 903

EP - 911

JO - Biosensors and Bioelectronics

JF - Biosensors and Bioelectronics

IS - 9

ER -

A new approach for creating double-stranded DNA biosensors

Résumé

Accès au document

Empreinte digitale

Contient cette citation