TY - JOUR
T1 - Two diketopiperazines and one halogenated phenol from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea
AU - Jiang, Zhong
AU - Boyd, Kenneth G.
AU - Mearns-spragg, Andrew
AU - Adams, David R.
AU - Wright, Phillip C.
AU - Burgess, J. Grant
N1 - Funding Information:
The authors thank Scottish Hospital Endowments Research Trust (RG9/99) and Natural and Environmental Research Council (GST/02/1633) for financial support. A. M-S. thanks Heriot-Watt University for the award of a University Scholarship. We also thank Prof. Sebastian Amyes (Department of Medical Microbiology, Edinburgh University) for providing MRSA 955 1, B. cepacia 5415, and E. coli EMG 9 for screening.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2000
Y1 - 2000
N2 - Two diketopiperazines, cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), and 2,4-dibromo-6-chlorophenol were isolated from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea. Cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline) stimulated antibiotic production in this strain. 2,4-Dibromo-6-chlorophenol showed antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and the cystic fibrosis associated pathogen Burkholderia cepacia.
AB - Two diketopiperazines, cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), and 2,4-dibromo-6-chlorophenol were isolated from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea. Cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline) stimulated antibiotic production in this strain. 2,4-Dibromo-6-chlorophenol showed antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and the cystic fibrosis associated pathogen Burkholderia cepacia.
KW - 2, 4-dibromo-6-chlorophenol
KW - Antibiotic
KW - Cyclo-(L-phenylalanyl-4R-hydroxy-L-proline)
KW - Cyclo-(L-prolyl-L-glycine)
KW - Pseudoalteromonas luteoviolacea
UR - https://www.scopus.com/pages/publications/0034487304
UR - https://www.scopus.com/pages/publications/0034487304#tab=citedBy
U2 - 10.1080/10575630008043781
DO - 10.1080/10575630008043781
M3 - Article
AN - SCOPUS:0034487304
SN - 1057-5634
VL - 14
SP - 435
EP - 440
JO - Natural Product Letters
JF - Natural Product Letters
IS - 6
ER -
Good health and well being