Tuning the Nitric Oxide Release from CPO-27 MOFs

Damiano Cattaneo; Stewart J Warrender; Morven J. Duncan; Christopher J Kelsall; Mary K Doherty; Phillip Whitfield; Ian Megson; Russell Morris

doi:10.1039/C5RA24023A

Tuning the Nitric Oxide Release from CPO-27 MOFs

Damiano Cattaneo
, Stewart J Warrender
, Morven J. Duncan
, Christopher J Kelsall
, Mary K Doherty
, Phillip Whitfield
, Ian Megson
, Russell Morris

Producción científica: Article › revisión exhaustiva

62 Citas (Scopus)

269 Descargas (Pure)

Resumen

Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

Idioma original	English
Páginas (desde-hasta)	14059-14067
Número de páginas	8
Publicación	RSC Adv.
Volumen	17
N.º	6
Fecha en línea anticipada	26 ene 2016
DOI	https://doi.org/10.1039/C5RA24023A
Estado	Published - 26 ene 2016

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10.1039/C5RA24023ALicencia: CC BY

Cattaneo_et_al_Tuning_the_Nitric_Oxide_Release_from_CPO_27_MOFS
© 2017 The Authors. Published by the Royal Society of Chemistry
Submitted manuscript, 2,54 MBLicencia: CC BY
Tuning the nitric oxide release from CPO-27 MOFs
© 2017 The Authors. Published by the Royal Society of Chemistry
Final published version, 2,62 MBLicencia: CC BY

http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C5RA24023ALicencia: CC BY

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abstract = "Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications",

author = "Damiano Cattaneo and Warrender, \{Stewart J\} and Duncan, \{Morven J.\} and Kelsall, \{Christopher J\} and Doherty, \{Mary K\} and Phillip Whitfield and Ian Megson and Russell Morris",

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AU - Cattaneo, Damiano

AU - Warrender, Stewart J

AU - Duncan, Morven J.

AU - Kelsall, Christopher J

AU - Doherty, Mary K

AU - Whitfield, Phillip

AU - Megson, Ian

AU - Morris, Russell

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N2 - Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

AB - Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications

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ER -

Tuning the Nitric Oxide Release from CPO-27 MOFs

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