N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

A T Treweeke; T J Winterburn; I Mackenzie; F Barrett; C Barr; G F Rushworth; I Dransfield; S M Macrury; I L Megson

doi:10.1007/s00125-012-2685-z

N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

A T Treweeke
, T J Winterburn
, I Mackenzie
, F Barrett
, C Barr
, G F Rushworth
, I Dransfield
, S M Macrury
, I L Megson

Producción científica: Article › revisión exhaustiva

42 Citas (Scopus)

Resumen

The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

Idioma original	English
Páginas (desde-hasta)	2920-8
Número de páginas	9
Publicación	Diabetologia
Volumen	55
N.º	11
DOI	https://doi.org/10.1007/s00125-012-2685-z
Estado	Published - 2012

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10.1007/s00125-012-2685-z

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Treweeke, A. T., Winterburn, T. J., Mackenzie, I., Barrett, F., Barr, C., Rushworth, G. F., Dransfield, I., Macrury, S. M., & Megson, I. L. (2012). N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial. Diabetologia, 55(11), 2920-8. https://doi.org/10.1007/s00125-012-2685-z

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abstract = "The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.",

author = "Treweeke, \{A T\} and Winterburn, \{T J\} and I Mackenzie and F Barrett and C Barr and Rushworth, \{G F\} and I Dransfield and Macrury, \{S M\} and Megson, \{I L\}",

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Treweeke, AT, Winterburn, TJ, Mackenzie, I, Barrett, F, Barr, C, Rushworth, GF, Dransfield, I, Macrury, SM & Megson, IL 2012, 'N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial', Diabetologia, vol. 55, n.º 11, pp. 2920-8. https://doi.org/10.1007/s00125-012-2685-z

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T2 - a randomised controlled trial

AU - Treweeke, A T

AU - Winterburn, T J

AU - Mackenzie, I

AU - Barrett, F

AU - Barr, C

AU - Rushworth, G F

AU - Dransfield, I

AU - Macrury, S M

AU - Megson, I L

PY - 2012

Y1 - 2012

N2 - The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

AB - The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

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DO - 10.1007/s00125-012-2685-z

M3 - Article

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SN - 1432-0428

VL - 55

SP - 2920

EP - 2928

JO - Diabetologia

JF - Diabetologia

IS - 11

ER -

N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

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