Evidence for co-dominant allelic expression of a phosphoglucomutase regulatory locus polymorphism in the Atlantic salmon

Starch gel electrophoresis of the phosphoglucomutase isozyme, PGM-1, in liver tissue in Atlantic salmon Salmo salar shows three phenotypes – full, partial and no expression. The genetic basis of the variation has not been established. Studies of the inheritance of the variation and of liver enzyme levels carried out indicate that the variation, as in rainbow trout Onchorynchus mykiss, reflects co-dominant allelic variation at a cis-acting regulatory locus, designated PGM-1r*, with one allele promoting and the other suppressing expression.