Systems biology approach in hypertension research

Christian Delles, Holger Husi

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3 Citations (Scopus)

Abstract

Systems biology is an approach to study all genes, gene transcripts, proteins, metabolites, and their interactions in specific cells, tissues, organs, or the whole organism. It is based on data derived from high-throughput analytical technologies and bioinformatics tools to analyze these data, and aims to understand the whole system rather than individual aspects of it. Systems biology can be applied to virtually all conditions and diseases and therefore also to hypertension and its underlying vascular disorders. Unlike other methods in this book there is no clear-cut protocol to explain a systems biology approach. We will instead outline some of the most important and common steps in the generation and analysis of systems biology data.
Original languageEnglish
Title of host publicationHypertension: Methods and Protocols
EditorsRhian M. Touyz, Ernesto L. Schriffin
Place of PublicationNew York
PublisherSpringer
Pages69-79
Number of pages11
Volume1527
DOIs
Publication statusPublished - 24 Jan 2017

Publication series

NameMethods in molecular biology
PublisherSpringer

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Delles, C., & Husi, H. (2017). Systems biology approach in hypertension research. In R. M. Touyz, & E. L. Schriffin (Eds.), Hypertension: Methods and Protocols (Vol. 1527, pp. 69-79). (Methods in molecular biology). New York: Springer. https://doi.org/10.1007/978-1-4939-6625-7_6