Persistent endothelial dysfunction in humans after diesel exhaust inhalation

Håkan Törnqvist; Nicholas L Mills; Manuel Gonzalez; Mark R Miller; Simon D Robinson; Ian L Megson; William Macnee; Ken Donaldson; Stefan Söderberg; David E Newby; Thomas Sandström; Anders Blomberg

doi:10.1164/rccm.200606-872OC

Persistent endothelial dysfunction in humans after diesel exhaust inhalation

Håkan Törnqvist
, Nicholas L Mills
, Manuel Gonzalez
, Mark R Miller
, Simon D Robinson
, Ian L Megson
, William Macnee
, Ken Donaldson
, Stefan Söderberg
, David E Newby
, Thomas Sandström
, Anders Blomberg

Research output: Contribution to journal › Article › peer-review

340 Citations (Scopus)

Abstract

Exposure to combustion-derived air pollution is associated with an early (1-2 h) and sustained (24 h) rise in cardiovascular morbidity and mortality. We have previously demonstrated that inhalation of diesel exhaust causes an immediate (within 2 h) impairment of vascular and endothelial function in humans.

Original language	English
Pages (from-to)	395-400
Number of pages	6
Journal	American Journal of Respiratory and Critical Care Medicine
Volume	176
Issue number	4
DOIs	https://doi.org/10.1164/rccm.200606-872OC
Publication status	Published - 2007

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Törnqvist, H., Mills, N. L., Gonzalez, M., Miller, M. R., Robinson, S. D., Megson, I. L., Macnee, W., Donaldson, K., Söderberg, S., Newby, D. E., Sandström, T., & Blomberg, A. (2007). Persistent endothelial dysfunction in humans after diesel exhaust inhalation. American Journal of Respiratory and Critical Care Medicine, 176(4), 395-400. https://doi.org/10.1164/rccm.200606-872OC

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abstract = "Exposure to combustion-derived air pollution is associated with an early (1-2 h) and sustained (24 h) rise in cardiovascular morbidity and mortality. We have previously demonstrated that inhalation of diesel exhaust causes an immediate (within 2 h) impairment of vascular and endothelial function in humans.",

author = "H{\aa}kan T{\"o}rnqvist and Mills, \{Nicholas L\} and Manuel Gonzalez and Miller, \{Mark R\} and Robinson, \{Simon D\} and Megson, \{Ian L\} and William Macnee and Ken Donaldson and Stefan S{\"o}derberg and Newby, \{David E\} and Thomas Sandstr{\"o}m and Anders Blomberg",

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doi = "10.1164/rccm.200606-872OC",

language = "English",

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Törnqvist, H, Mills, NL, Gonzalez, M, Miller, MR, Robinson, SD, Megson, IL, Macnee, W, Donaldson, K, Söderberg, S, Newby, DE, Sandström, T & Blomberg, A 2007, 'Persistent endothelial dysfunction in humans after diesel exhaust inhalation', American Journal of Respiratory and Critical Care Medicine, vol. 176, no. 4, pp. 395-400. https://doi.org/10.1164/rccm.200606-872OC

TY - JOUR

T1 - Persistent endothelial dysfunction in humans after diesel exhaust inhalation

AU - Törnqvist, Håkan

AU - Mills, Nicholas L

AU - Gonzalez, Manuel

AU - Miller, Mark R

AU - Robinson, Simon D

AU - Megson, Ian L

AU - Macnee, William

AU - Donaldson, Ken

AU - Söderberg, Stefan

AU - Newby, David E

AU - Sandström, Thomas

AU - Blomberg, Anders

PY - 2007

Y1 - 2007

N2 - Exposure to combustion-derived air pollution is associated with an early (1-2 h) and sustained (24 h) rise in cardiovascular morbidity and mortality. We have previously demonstrated that inhalation of diesel exhaust causes an immediate (within 2 h) impairment of vascular and endothelial function in humans.

AB - Exposure to combustion-derived air pollution is associated with an early (1-2 h) and sustained (24 h) rise in cardiovascular morbidity and mortality. We have previously demonstrated that inhalation of diesel exhaust causes an immediate (within 2 h) impairment of vascular and endothelial function in humans.

U2 - 10.1164/rccm.200606-872OC

DO - 10.1164/rccm.200606-872OC

M3 - Article

C2 - 17446340

SN - 1073-449X

VL - 176

SP - 395

EP - 400

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

IS - 4

ER -

Persistent endothelial dysfunction in humans after diesel exhaust inhalation

Abstract

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