No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample

Heyao Li, Haiying Zhang, Libo Liu, Guizhi Ju, Shunzi Jin, Lin Ye, Xuan Zhang, Jun Wei

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Abstract

The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.
Original languageEnglish
Pages (from-to)176-7
Number of pages2
JournalPsychiatry Research
Volume169
Issue number2
DOIs
Publication statusPublished - 30 Sep 2009

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Keywords

  • Adult
  • Asian Continental Ancestry Group
  • Case-Control Studies
  • Chi-Square Distribution
  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Phosphatidylethanolamine N-Methyltransferase
  • Polymorphism, Single Nucleotide
  • Schizophrenia
  • Young Adult

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