N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

A T Treweeke, T J Winterburn, I Mackenzie, F Barrett, C Barr, G F Rushworth, I Dransfield, S M Macrury, I L Megson

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Abstract

The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.
Original languageEnglish
Pages (from-to)2920-8
Number of pages9
JournalDiabetologia
Volume55
Issue number11
DOIs
Publication statusPublished - 2012

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