Abstract
Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications
This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed.
This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed.
| Original language | English |
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| Title of host publication | Integration of Omics Approaches and Systems Biology for Clinical Applications |
| Editors | Antonia Vlahou, Harald Mischak, Jerome Zoidakis, Fulvio Magni |
| Place of Publication | Hoboken, USA |
| Publisher | Wiley-Blackwell |
| Chapter | 20 |
| Pages | 327-346 |
| Number of pages | 20 |
| ISBN (Print) | 9781119181149 |
| Publication status | Published - 2018 |
Publication series
| Name | Wiley Series on Mass Spectrometry |
|---|---|
| Publisher | Wiley Blackwell |