TY - JOUR
T1 - Isolation and synthesis of tanyolides A and B, metabolites of the nudibranch Sclerodoris tanya.
AU - Krug, Patrick J.
AU - Boyd, Kenneth G.
AU - John Faulkner, D.
N1 - Funding Information:
We thank Mary Kay Harper and Robert F. Snodgrass for assistance with collecting nudibranchs and Dr. Joseph Pawlik for discussions of bioassay techniques. This research was generously supported by a grant from the National Science Foundation (CHE 92-04647) and by a NSF predoctoral fellowship to PJK.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1995/10/9
Y1 - 1995/10/9
N2 - The nudibranch Sclerodoris tanya, which was collected intertidally at La Jolla, contains two sesquiterpene glyceride esters, tanyolides A (4) and B (5). The structures of the tanyolides were elucidated by interpretation of spectral data. The absolute configuration of tanyolide B (5) was determined by synthesis of both enantiomers and the structure of tanyolide A (4) was also confirmed by synthesis. The tanyolides, which are located primarily in the dorsal mantle, deter feeding by two ecologically-relevant predatory fish.
AB - The nudibranch Sclerodoris tanya, which was collected intertidally at La Jolla, contains two sesquiterpene glyceride esters, tanyolides A (4) and B (5). The structures of the tanyolides were elucidated by interpretation of spectral data. The absolute configuration of tanyolide B (5) was determined by synthesis of both enantiomers and the structure of tanyolide A (4) was also confirmed by synthesis. The tanyolides, which are located primarily in the dorsal mantle, deter feeding by two ecologically-relevant predatory fish.
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U2 - 10.1016/0040-4020(95)00679-3
DO - 10.1016/0040-4020(95)00679-3
M3 - Article
AN - SCOPUS:0029145723
SN - 0040-4020
VL - 51
SP - 11063
EP - 11074
JO - Tetrahedron
JF - Tetrahedron
IS - 41
ER -