HbA1c determination from HemaSpot? blood collection devices: comparison of home prepared dried blood spots with standard venous blood analysis

Jennifer Hall, Claire Fowler, Fiona Barrett, Roger Humphry, Marie Van Drimmelen, Sandra MacRury

Research output: Contribution to journalArticle

4 Citations (Scopus)
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Abstract

Aim
To assess the clinical performance and patient acceptance of HemaSpot™ blood collection devices as an alternative blood collection method.

Methods
Adult men and women with any type of diabetes, routinely carrying out self‐monitoring of blood glucose were recruited (n = 128). Participants provided a venous blood sample and prepared two HemaSpot dried blood spots, one at clinics and one at home. HbA1c analysis was by Tosoh G8 high‐performance liquid chromatography. Participants also completed a questionnaire.

Results
Strong linear relationships been HbA1c levels in dried blood spots and venous blood were observed and a linear model was fitted to the data. Time between dried blood spot preparation and testing did not impact the model. Participants were accepting of the approach: 69.2% would use this system if available and 60.7% would be more likely to use this system than going to their general practitioner.

Conclusions
The combination of a robust desiccating dried blood spot device, home sample preparation and return by post produces HbA1c data that support the use of a time‐independent linear calibration of dried blood spot to venous blood HbA1c. A robust remote sample collection service would be valuable to people living with diabetes in urban areas who are working or house‐bound as well as those living in remote or rural locations.
Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalDiabetic Medicine
Early online date16 Aug 2019
DOIs
Publication statusPublished - Oct 2019

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