Effect of intravenous lipid emulsions on hepatic cholesterol metabolism

P D Whitfield, P T Clayton, D P Muller

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


Total parenteral nutrition offers the chance of survival to children who have had extensive gut resections or gut failure. However, in infants it is often associated with serious complications including cholestatic liver disease. The causes of these complications remain unclear, although it has been suggested that the lipid emulsions used in total parenteral nutrition may be responsible.
Original languageEnglish
Pages (from-to)538-46
Number of pages9
JournalJournal of Pediatric Gastroenterology and Nutrition
Issue number5
Publication statusPublished - May 2000


  • Carcinoma, Hepatocellular
  • Cholesterol
  • Culture Media
  • Fat Emulsions, Intravenous
  • Humans
  • Kinetics
  • Liver
  • Liver Neoplasms
  • Phospholipids
  • Triglycerides
  • Tumor Cells, Cultured


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