Abstract
In the present study, five allelic fragments were typed by a polymerase chain reaction (PCR) process with a pair of primers specific for the tetranucleotide (TCAT) repeat sequence in the first intron of the human tyrosine hydroxylase (TH) gene and their sizes (bp) were 114 (A), 118 (B), 122 (C), 126 (D) and 130 (E), respectively. The AE genotypic frequency was found to be significantly higher in unrelated patients with schizophrenia than in unrelated control subjects (chi 2 = 4.18, p
Original language | English |
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Pages (from-to) | 83-8 |
Number of pages | 6 |
Journal | Psychiatric Genetics |
Volume | 5 |
Issue number | 2 |
Publication status | Published - 1995 |
Keywords
- Adult
- Alleles
- Base Sequence
- Catecholamines
- Female
- Great Britain
- Humans
- Introns
- Male
- Microsatellite Repeats
- Middle Aged
- Minisatellite Repeats
- Molecular Sequence Data
- Nerve Tissue Proteins
- Norepinephrine
- Polymerase Chain Reaction
- Schizophrenia
- Tyrosine 3-Monooxygenase