Abstract
Preliminary investigations on the detection of nucleic acid hybridisation by direct electrochemical techniques are described. Initial experiments were performed with calf thymus DNA, while as a model system, plasmid DNA (pEMBL) which can be prepared in single stranded forms from each of two original double stranded plasmids (+19 and -19) was used. Electrochemical analyses have been performed using mercury pool, glassy carbon and screen printed carbon working electrodes.
| Original language | English |
|---|---|
| Pages (from-to) | 21-28 |
| Number of pages | 8 |
| Journal | Biochemistry and molecular biology international |
| Volume | 32 |
| Issue number | 1 |
| Publication status | Published - Jan 1994 |
Keywords
- Animals
- Biosensing Techniques
- Calibration
- Carbon
- DNA, Complementary
- DNA, Single-Stranded
- Electrochemistry
- Hydrogen-Ion Concentration
- Nucleic Acid Hybridization