A study of enzymes involved in catecholamine metabolism in parents of patients with schizophrenia

J Wei, C N Ramchand, A E Clark, G P Hemmings

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The concentrations of serum homovanillic acid (HVA), norepinephrine (NE), tyrosine (Tyr), phenylalanine (Phe) and tryptophan (Trp), and the activities of serum dopamine-beta-hydroxylase (DBH), platelet monoamine oxidase (MAO), and erythrocyte catechol-O-methyl transferase (COMT) were measured in 68 healthy parents who had schizophrenic offspring. The results show a significant correlation between the parents of schizophrenic patients in serum HVA (r=0.38, n=34, p
Original languageEnglish
Pages (from-to)27-32
Number of pages6
JournalSchizophrenia Research
Issue number1
Publication statusPublished - Mar 1996



  • Adult
  • Aged
  • Amino Acids
  • Brain
  • Catecholamines
  • Humans
  • Middle Aged
  • Random Allocation
  • Schizophrenia

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