This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of ¿-glutamyl transpeptidase (¿-GT), and have potential for the treatment of acute renal injury/failure (ARI/ARF).
|Number of pages||3|
|Publication status||Published - 18 Feb 2013|
- Acute Kidney Injury
- Nitric Oxide
- Vasodilator Agents