A community perspective on the concept of marine holobionts: current status, challenges, and future directions

Simon M. Dittami, Enrique Arboleda, Jean-christophe Auguet, Arite Bigalke, Enora Briand, Paco Cárdenas, Ulisse Cardini, Johan Decelle, Aschwin H. Engelen, Damien Eveillard, Claire M.m. Gachon, Sarah M. Griffiths, Tilmann Harder, Ehsan Kayal, Elena Kazamia, François H. Lallier, Mónica Medina, Ezequiel M. Marzinelli, Teresa Maria Morganti, Laura Núñez PonsSoizic Prado, José Pintado, Mahasweta Saha, Marc-andré Selosse, Derek Skillings, Willem Stock, Shinichi Sunagawa, Eve Toulza, Alexey Vorobev, Catherine Leblanc, Fabrice Not

Research output: Contribution to journalLiterature reviewpeer-review

3 Citations (Scopus)
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Abstract

Host-microbe interactions play crucial roles in marine ecosystems. However, we still have very little understanding of the mechanisms that govern these relationships, the evolutionary processes that shape them, and their ecological consequences. The holobiont concept is a renewed paradigm in biology that can help to describe and understand these complex systems. It posits that a host and its associated microbiota with which it interacts, form a holobiont, and have to be studied together as a coherent biological and functional unit to understand its biology, ecology, and evolution. Here we discuss critical concepts and opportunities in marine holobiont research and identify key challenges in the field. We highlight the potential economic, sociological, and environmental impacts of the holobiont concept in marine biological, evolutionary, and environmental sciences. Given the connectivity and the unexplored biodiversity specific to marine ecosystems, a deeper understanding of such complex systems requires further technological and conceptual advances, e.g., the development of controlled experimental model systems for holobionts from all major lineages and the modeling of (info)chemical-mediated interactions between organisms. Here we propose that one significant challenge is to bridge cross-disciplinary research on tractable model systems in order to address key ecological and evolutionary questions. This first step is crucial to decipher the main drivers of the dynamics and evolution of holobionts and to account for the holobiont concept in applied areas, such as the conservation, management, and exploitation of marine ecosystems and resources, where practical solutions to predict and mitigate the impact of human activities are more important than ever.
Original languageEnglish
Article numbere10911
Number of pages34
JournalPeerJ
Volume9
DOIs
Publication statusPublished - 25 Feb 2021

Keywords

  • Evolution
  • Ecosystem services
  • Symbiosis
  • Host-microbiota interactions
  • Marine holobionts
  • Dysbiosis

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