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  • Antonia Pritchard
2020

Pan-cancer analysis of whole genomes

Pritchard, A., 5 Feb 2020, In : Nature. 578, 7793, p. 82-93 12 p.

Research output: Contribution to journalArticle

Open Access
File
80 Citations (Scopus)
4 Downloads (Pure)

Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours

Johansson, P. A., Brooks, K., Newell, F., Palmer, J. M., Wilmott, J. S., Pritchard, A. L., Broit, N., Wood, S., Carlino, M. S., Leonard, C., Koufariotis, L. T., Nathan, V., Beasley, A. B., Howlie, M., Dawson, R., Rizos, H., Schmidt, C. W., Long, G. V., Hamilton, H., Kiilgaard, J. F. & 15 others, Isaacs, T., Gray, E. S., Rolfe, O. J., Park, J. J., Stark, A., Mann, G. J., Scolyer, R. A., Pearson, J. V., Van Baren, N., Waddell, N., Wadt, K. W., Mcgrath, L. A., Warrier, S. K., Glasson, W. & Hayward, N. K., 15 May 2020, In : Nature Communications. 11, p. 1-8 8 p., 2408 (2020).

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
14 Downloads (Pure)
2019

Bone marrow transplantation generates T cell-dependent control of myeloma in mice

Vuckovic, S., Minnie, S. A., Smith, D., Gartlan, K. H., Watkins, T. S., Markey, K. A., Mukhopadhyay, P., Guillerey, C., Kuns, R. D., Locke, K. R., Pritchard, A. L., Johansson, P. A., Varelias, A., Zhang, P., Huntington, N. D., Waddell, N., Chesi, M., Miles, J. J., Smyth, M. J. & Hill, G. R., 2 Jan 2019, In : Journal of Clinical Investigation. 129, 1, p. 106-121 16 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Clinical Epigenetics

Pritchard, A. (ed.) & Hesson, L. (ed.), Sep 2019, Springer Nature. 265 p.

Research output: Book/ReportBook

Open Access
File
2 Citations (Scopus)

Evaluation of the contribution of germline variants in BRCA1 and BRCA2 to uveal and cutaneous melanoma

Johansson, P. A., Nathan, V., Bourke, L. M., Palmer, J. M., Zhang, T., Symmons, J., Howlie, M., Patch, A. M., Read, J., Holland, E. A., Schmid, H., Warrier, S., Glasson, W., Höiom, V., Wadt, K., Jönsson, G., Olsson, H., Ingvar, C., Mann, G., Brown, K. M. & 2 others, Hayward, N. K. & Pritchard, A. L., 1 Oct 2019, In : Melanoma Research. 29, 5, p. 483-490 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genetics and Epigenetics: A Historical Overview

Hesson, L. B. & Pritchard, A. L., 1 Sep 2019, Clinical Epigenetics. Springer Nature, p. 1-46 46 p. (Clinical Epigenetics).

Research output: Chapter in Book/Report/Conference proceedingChapter

Germline variants in oculocutaneous albinism genes and predisposition to familial cutaneous melanoma

Nathan, V., Johansson, P. A., Palmer, J. M., Howlie, M., Hamilton, H. R., Wadt, K., Jönsson, G., Brooks, K. M., Pritchard, A. L. & Hayward, N. K., 24 Jun 2019, In : Pigment Cell and Melanoma Research. 32, 6, p. 854-863 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Prolonged stable disease in a uveal melanoma patient with germline MBD4 nonsense mutation treated with pembrolizumab and ipilimumab

Johansson, P. A., Stark, A., Palmer, J. M., Bigby, K., Brooks, K., Rolfe, O., Pritchard, A. L., Whitehead, K., Warrier, S., Glasson, W. & Hayward, N. K., 1 May 2019, In : Immunogenetics. 71, 5-6, p. 433-436 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The Clinical Utility of Epigenetics: A Case Study

Hesson, L. B., Sloane, M. A. & Pritchard, A. L., 1 Sep 2019, Clinical Epigenetics. Springer Nature, p. 247-265 19 p. (Clinical Epigenetics).

Research output: Chapter in Book/Report/Conference proceedingChapter

The Role of Histone Variants in Cancer

Pritchard, A. L., 1 Sep 2019, Clinical Epigenetics. Hesson, L. (ed.). Springer Nature, p. 133-151 19 p. (Clinical Epigenetics).

Research output: Chapter in Book/Report/Conference proceedingChapter

Whole genome sequencing of melanomas in adolescent and young adults reveals distinct mutation landscapes and the potential role of germline variants in disease susceptibility

Wilmott, J. S., Johansson, P. A., Newell, F., Waddell, N., Ferguson, P., Quek, C., Patch, A-M., Nones, K., Shang, P., Pritchard, A. L., Kazakoff, S., Holmes, O., Leonard, C., Wood, S., Xu, Q., Saw, R. P. M., Spillane, A. J., Stretch, J. R., Shannon, K. F., Kefford, R. F. & 7 others, Menzies, A. M., Long, G. V., Thompson, J. F., Pearson, J. V., Mann, G. J., Hayward, N. K. & Scolyer, R. A., 1 Mar 2019, In : International Journal of Cancer. Journal International du Cancer. 144, 5, p. 1049-1060 12 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
11 Downloads (Pure)
2018

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide

4 Dec 2018, In : JNCI: Journal of the National Cancer Institute. 110, 12, p. 1328-1341 14 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers

Pritchard, A. L., Johansson, P. A., Nathan, V., Howlie, M., Symmons, J., Palmer, J. M. & Hayward, N. K., 11 Apr 2018, In : PLoS ONE. 13, 4, p. e0194098

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
26 Downloads (Pure)

Germline variants of BAP1 in the Australian population: Journal of Clinical Oncology

Walpole, S., Pritchard, A., Palmer, J., Howlie, M., Symmons, J., Hamilton, H., Glasson, W., Warrier, S., Rolfe, O., Stark, A., D'Mellow, M. & Hayward, N., 1 Jun 2018, In : Journal of Clinical Oncology. 36, 15 Suppl, p. e13534-e13534

Research output: Contribution to journalMeeting abstract

Identifying neoantigens for use in immunotherapy

Hutchison, S. & Pritchard, A. L., 24 Aug 2018, In : Mammalian Genome. p. 1-17 17 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
148 Downloads (Pure)

Targeting Neoantigens for Personalised Immunotherapy

Pritchard, A. L., 1 Apr 2018, In : BioDrugs. 32, 2, p. 99-109 11 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
8 Downloads (Pure)
2017

Abstract 3717: New therapies for the treatment of BRAF/NRAS wild type melanoma: Cancer Research

Ranzani, M., Kemper, K., Michaut, M., Krijgsman, O., Iyer, V., Speak, A., Nsengimana, J., Wong, K., Grinkevich, V., Aben, N., Velasco-Herrera, M. D. C., Alsinet, C., Sjoberg, M., Rashid, M., Turner, G., Behan, F., Supper, E., Thompson, N., Bignell, G., Dutton-Regester, K. & 10 others, Pritchard, A., Wong, C., McDermott, U., Hayward, N. K., Yusa, K., Newton-Bishop, J., Wessels, L., Garnett, M., Peeper, D. & Adams, D., 2017, In : Cancer Research. 77, 13 Suppl, p. 3717 1 p.

Research output: Contribution to journalMeeting abstract

Abstract LB-031: Deciphering distinct roles of RASA2 in melanomagenesis: Cancer Research

Arafeh, R., Qutob, N., Emmanuel, R. R., Madore, J., Elkahloun, A., Wilmott, J. S. J. S., Gartner, J. J., Pizio, A. D., Rotkopf, R., Dutton-Regester, K., Hill, V., Pritchard, A., Lin, J. C., Rosenberg, S. A., Khan, J., Ben-Dor, S., Niv, M. Y. M. Y., Ulitsky, I., Mann, G. J., Scolyer, R. A. & 2 others, Hayward, N. K. & Samuels, Y., 2017, In : Cancer Research. 77, 13 Suppl, p. LB-031-LB-031

Research output: Contribution to journalMeeting abstract

Open Access

Germline Variation at CDKN2A and Associations with Nevus Phenotypes among Members of Melanoma Families

Taylor, N. J., Mitra, N., Goldstein, A. M., Tucker, M. A., Avril, M., Azizi, E., Bergman, W., Bishop, D. T., Bressac-de Paillerets, B., Bruno, W., Calista, D., Cannon-albright, L. A., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Gerdes, A., Ghiorzo, P., Grazziotin, T. C., Hansson, J. & 24 others, Harland, M., Hayward, N. K., Hocevar, M., Höiom, V., Ingvar, C., Landi, M. T., Landman, G., Larre-borges, A., Leachman, S. A., Mann, G. J., Nagore, E., Olsson, H., Palmer, J. M., Perić, B., Pjanova, D., Pritchard, A., Puig, S., Van Der Stoep, N., Wadt, K. A. W., Whitaker, L., Yang, X. R., Newton Bishop, J. A., Gruis, N. A. & Kanetsky, P. A., 1 Dec 2017, In : Journal of Investigative Dermatology. 137, 12, p. 2606-2612 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Intergenic disease-associated regions are abundant in novel transcripts

Bartonicek, N., Clark, MB., Quek, X. C., Torpy, J. R., Pritchard, A. L., Maag, J. L. V., Gloss, B. S., Crawford, J., Taft, R. J., Hayward, N. K., Montgomery, G. W., Mattick, J. S., Mercer, T. R. & Dinger, M. E., 28 Dec 2017, In : Genome Biology. 18, 16 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
97 Downloads (Pure)

Mutation load in melanoma is affected by MC1R genotype

Johansson, P. A., Pritchard, A. L., Patch, A-M., Wilmott, J. S., Pearson, J. V., Waddell, N., Scolyer, R. A., Mann, G. J. & Hayward, N. K., 7 Mar 2017, In : Pigment Cell and Melanoma Research. 30, 2, p. 255-258 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Novel germline variants in cutaneous and uveal melanoma families

Hayward, N. K., Pritchard, A., Johansson, P. A., Aoude, L. G., Jonsson, G., Hoiom, V. & Wadt, K., 20 Jun 2017, In : Journal of the European Academy of Dermatology and Venereology. 31, p. 46-46 1 p.

Research output: Contribution to journalMeeting abstract

Novel high risk genes of melanoma

Hayward, N. K., Pritchard, A., Johansson, P. A., Aoude, L. G., Jonsson, G., Hoiom, V., Wadt, K. & Adams, DR., Jun 2017, In : European Journal of Human Genetics.

Research output: Contribution to journalMeeting abstract

26 Citations (Scopus)

Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma

McEvoy, A. C., Calapre, L., Pereira, M. R., Giardina, T., Robinson, C., Khattak, M. A., Meniawy, T. M., Pritchard, A. L., Hayward, N. K., Amanuel, B., Millward, M., Ziman, M. & Gray, E. S., 3 Oct 2017, In : Oncotarget. 8, 45, p. 78890-78900 11 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
62 Downloads (Pure)

Whole-genome landscapes of major melanoma subtypes

Hayward, N. K., Wilmott, J. S., Waddell, N., Johansson, P. A., Field, M. A., Nones, K., Patch, A-M., Kakavand, H., Alexandrov, L. B., Burke, H., Jakrot, V., Kazakoff, S., Holmes, O., Leonard, C., Sabarinathan, R., Mularoni, L., Wood, S., Xu, Q., Waddell, N., Tembe, V. & 29 others, Pupo, G. M., De Paoli-Iseppi, R., Vilain, R. E., Shang, P., Lau, L. M. S., Dagg, R. A., Schramm, S-J., Pritchard, A., Dutton-Regester, K., Newell, F., Fitzgerald, A., Shang, C. A., Grimmond, S. M., Pickett, H. A., Yang, J. Y., Stretch, J. R., Behren, A., Kefford, R. F., Hersey, P., Long, G. V., Cebon, J., Shackleton, M., Spillane, A. J., Saw, R. P. M., Lopez-Bigas, N., Pearson, J. V., Thompson, J. F., Scolyer, R. A. & Mann, G. J., 11 May 2017, In : Nature. 545, 7653, p. 175-180 6 p.

Research output: Contribution to journalArticle

335 Citations (Scopus)
2016

Identification of new therapies for the treatment of BRAF/NRAS wild-type melanomas by functional screening approaches

Ranzani, M., Michaut, M., Alsinet, C., Grinkevich, V., Wong, K., Iyer, V., Aben, N., Velasco-Herrera, M. D. C., Sjoberg, M., Rashid, M., Bignell, G., Dutton-Regester, K., Pritchard, A., Vis, D., Turner, G., McDermott, U., Hayward, N. K., Yusa, K., Wessels, L., Garnett, M. & 1 others, Adams, D., Jul 2016, In : Cancer Research. 76, 14, pp 4783.

Research output: Contribution to journalArticle