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  • Holger Husi
2020

Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma

Voigtländer, T., Metzger, J., Husi, H., Kirstein, M. M., Pejchinovski, M., Latosinska, A., Frantzi, M., Mullen, W., Book, T., Mischak, H. & Manns, M. P., 3 Jan 2020, In : Journal of Biomedical Science. 27, 13, p. 1-14 14 p.

Research output: Contribution to journalArticle

Open Access
File

The influence of hypoxia on the prostate cancer proteome

Ross, J. A., Vissers, J. P. C., Nanda, J., Stewart, G. D., Husi, H., Habib, F. K., Hammond, D. E. & Gethings, L. A., 2020, In : Clinical Chemistry and Laboratory Medicine.

Research output: Contribution to journalArticle

2019
Open Access
File
33 Downloads (Pure)

Cheminformatics and Computational Approaches in Metabolomics

Fernandes, M., Sanches, B. & Husi, H., 1 Nov 2019, Computational Biology. Brisbane, Australia: Codon Publications, p. 143-160 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Open Access
File
1 Downloads (Pure)

Computational Approaches in Proteomics

Cervantes-Gracia, K. & Husi, H., 31 Oct 2019, Computational Biology. Brisbane, Australia: Codon Publications, p. 119-142 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
File
2 Downloads (Pure)

Computational Biology

Husi, H., 1 Nov 2019, 1 ed. Brisbane, Australia: Codon Publications. 194 p.

Research output: Book/ReportBook

Open Access
File

Proteomic strategies to unravel age-related redox signalling defects in skeletal muscle

Cobley, J. N., Sakellariou, G. K., Husi, H. & McDonagh, B., 20 Feb 2019, In : Free Radical Biology & Medicine. 132, p. 24-32 9 p.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
4 Downloads (Pure)
2018

Acute stress alters the rates of degradation of cardiac muscle proteins

Geary, B., Magee, K., Cash, P., Husi, H., Young, I. S., Whitfield, P. D. & Doherty, M. K., 22 Mar 2018, In : Journal of Proteomics. 7 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
10 Downloads (Pure)

C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD)

Fernandes, M., Patel, A. & Husi, H., 12 Nov 2018, In : PLoS ONE. 13, 11, p. 1-28 28 p., e0207371.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
64 Downloads (Pure)

Database Creation and Utility

Krochmal, M., Cisek, K. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 286-300 15 p. (Wiley Series on Mass Spectrometry).

Research output: Chapter in Book/Report/Conference proceedingChapter

Integrative analysis of Multiple Sclerosis using a systems biology approach

Cervantes-Gracia, K. & Husi, H., 4 Apr 2018, In : Scientific Reports. 8, p. 1-14 14 p., 5633.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
101 Downloads (Pure)

Knowledge Discovery and Data Mining

Krochmal, M. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 233-247 15 p. (Wiley Series on Mass Spectrometry).

Research output: Chapter in Book/Report/Conference proceedingChapter

MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells

Valiño-Rivas, L., Cuarental, L., Agustin, M., Husi, H., Cannata-Ortiz, P., Sanz, A. B., Mischak, H., Ortiz, A. & Sanchez-Niño, M. D., 11 Dec 2018, In : Nephrology, Dialysis, Transplantation. p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
3 Downloads (Pure)

Molecular Model for CKD

Fernandes, M., Cisek, K. & Husi, H., 2018, Integration of Omics Approaches and Systems Biology for Clinical Applications. Vlahou, A., Mischak, H., Zoidakis, J. & Magni, F. (eds.). Hoboken, USA: Wiley-Blackwell, p. 327-346 20 p. (Wiley Series on Mass Spectrometry).

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteomic identification of potential markers of myosteatosis in human urine

Husi, H., MacDonald, A., Skipworth, R. J. E., Miller, J., Cronshaw, A., Fearon, K. C. H. & Ross, J. A., 25 Apr 2018, In : Biomedical Reports. 8, p. 557-564 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
60 Downloads (Pure)

Proteomics and Metabolomics for AKI Diagnosis

Marx, D., Metzger, J., Pejchinovski, M., Gil, R. B., Frantzi, M., Latosinska, A., Belczacka, I., Heinzmann, S. S., Husi, H., Zoidakis, J., Klingele, M. & Herget-Rosenthal, S., Jan 2018, In : Seminars in Nephrology. 38, 1, p. 63-87 25 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
29 Downloads (Pure)

The Many Facets of Fabry Disease in the Kidney-Heart Axis

Fernandes, M. & Husi, H., 15 Nov 2018, In : Journal of Nephrology and Kidney Diseases . 1, 2, p. 1-4 4 p., 120.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
40 Downloads (Pure)

Urinary diagnostic proteomic markers for dynapenia in cancer patients

Husi, H., MacDonald, A., Skipworth, R. J. E., Miller, J., Cronshaw, A., Greig, C., Fearon, K. C. H. & Ross, J. A., 25 Apr 2018, In : Biomedical Reports. 8, 6, p. 547-556 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
71 Downloads (Pure)
2017

CVD and oxidative stress

Gracia, K. C., Llanas-Cornejo, D. & Husi, H., 20 Feb 2017, In : Journal of Clinical Medicine. 6, 2

Research output: Contribution to journalArticle

Open Access

Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD)

Fernandes, M. & Husi, H., 12 Jan 2017, In : Scientific Reports. 7, 40367.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Mitogen-activated protein kinase 14 promotes AKI

Ortiz, A., Husi, H., Gonzalez-Lafuente, L., Valiño-Rivas, L., Fresno, M., Sanz, A. B., Mullen, W., Albalat, A., Mezzano, S., Vlahou, T., Mischak, H. & Sanchez-Niño, M. D., 1 Mar 2017, In : Journal of the American Society of Nephrology. 28, 3, p. 823-836 14 p.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

Systems biology approach in hypertension research

Delles, C. & Husi, H., 24 Jan 2017, Hypertension: Methods and Protocols. Touyz, R. M. & Schriffin, E. L. (eds.). New York: Springer, Vol. 1527. p. 69-79 11 p. (Methods in molecular biology).

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

3 Citations (Scopus)

Tissue proteomics in vascular disease

Albalat, A., Mullen, W., Husi, H. & Mischak, H., 24 Jan 2017, Hypertension: Methods and Protocols. Touyz, R. M. & Schiffrin, E. L. (eds.). New York: Springer New York, Vol. 1527. p. 53-60 8 p. (Methods in molecular biology).

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

1 Citation (Scopus)

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy

Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H. & Vlahou, A., 9 Nov 2017, In : Scientific Reports. 7, 1, 15160.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
75 Downloads (Pure)
2016

Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study

Metzger, J., Mullen, W., Husi, H., Stalmach, A., Herget-Rosenthal, S., Groesdonk, H., Mischak, H. & Klingele, M., 2016, In : Critical Care. 20

Research output: Contribution to journalArticle

14 Citations (Scopus)

Development of a MALDI MS-based platform for early detection of acute kidney injury

Carrick, E., Vanmassenhove, J., Glorieux, G., Metzger, J., Dakna, M., Pejchinovski, M., Jankowski, V., Mansoorian, B., Husi, H., Mullen, W., Mischak, H., Vanholder, R. & Biesen, W. V., 1 Jul 2016, In : Proteomics Clinical Applications. 10, 7, p. 732-742 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma

Chaudhuri, R., McSharry, C., Heaney, L. G., Niven, R., Brightling, C. E., Menzies-Gow, A. N., Bucknall, C., Mansur, A. H., Lee, W., Shepherd, M., Spears, M., Cowan, D. C., Husi, H. & Thomson, N. C., 1 Sep 2016, In : Respiratory Medicine. 118, p. 46-52 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Integrative systems biology investigation of Fabry disease

Fernandes, M. & Husi, H., 1 Nov 2016, In : Diseases. 4, 4

Research output: Contribution to journalArticle

Open Access

Omics databases on kidney disease: where they can be found and how to benefit from them

Papadopoulos, T., Krochmal, M., Cisek, K., Fernandes, M., Husi, H., Stevens, R., Bascands, J-L., Schanstra, J. P. & Klein, J., 1 Jun 2016, In : Clinical Kidney Journal. 9, 3, p. 343-352 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease

Krochmal, M., Fernandes, M., Filip, S., Pontillo, C., Husi, H., Zoidakis, J., Mischak, H., Vlahou, A. & Jankowski, J., 1 Sep 2016, In : Database.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
17 Downloads (Pure)

Proteomic identification of potential cancer markers in human urine using subtractive analysis

Husi, H., Skipworth, R. J. E., Cronshaw, A., Fearon, K. C. H. & Ross, J. A., 1 May 2016, In : International Journal of Oncology. 48, 5, p. 1921-1932 12 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Proteomics for rejection diagnosis in renal transplant patients: where are we now?

Gwinner, W., Metzger, J., Husi, H. & Marx, D., 1 Mar 2016, In : World Journal of Transplantation. 6, 1, p. 28-41 14 p.

Research output: Contribution to journalArticle

Urinary peptide analysis differentiates pancreatic cancer from chronic pancreatitis

Schönemeier, B., Metzger, J., Klein, J., Husi, H., Bremer, B., Armbrecht, N., Dakna, M., Schanstra, J. P., Rosendahl, J., Wiegand, J., Jäger, M., Mullen, W., Breuil, B., Plentz, R. R., Lichtinghagen, R., Brand, K., Kühnel, F., Mischak, H., Manns, M. P. & Lankisch, T. O., 1 Aug 2016, In : Pancreas. 45, 7, p. 1018-1026 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2015

Cerebrospinal fluid prohormone processing and neuropeptides stimulating feed intake of dairy cows during early lactation

Kuhla, B., Laeger, T., Husi, H. & Mullen, W., 1 Feb 2015, In : Journal of Proteome Research. 14, 2, p. 823-828 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Diagnosis and prediction of CKD progression by assessment of urinary peptides

Schanstra, J. P., Zurbig, P., Alkhalaf, A., Argiles, A., Bakker, S. J. L., Beige, J., Bilo, H. J. G., Chatzikyrkou, C., Dakna, M., Dawson, J., Delles, C., Haller, H., Haubitz, M., Husi, H., Jankowski, J., Jerums, G., Kleefstra, N., Kuznetsova, T., Maahs, D. M., Menne, J. & 14 others, Mullen, W., Ortiz, A., Persson, F., Rossing, P., Ruggenenti, P., Rychlik, I., Serra, A. L., Siwy, J., Snell-Bergeon, J., Spasovski, G., Staessen, J. A., Vlahou, A., Mischak, H. & Vanholder, R., 1 Aug 2015, In : Journal of the American Society of Nephrology. 26, 8, p. 1999-2010 12 p.

Research output: Contribution to journalArticle

118 Citations (Scopus)

Habitual myofibrillar protein synthesis is normal in patients with upper GI cancer cachexia

MacDonald, A. J., Johns, N., Stephens, N. A., Greig, C. A., Ross, J. A., Small, A. C., Husi, H., Fearon, K. C. H. & Preston, T., 1 Apr 2015, In : Clinical Cancer Research. 21, 7, p. 1734-1740 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Methods in capillary electrophoresis coupled to mass spectrometry for the identification of clinical proteomic/peptidomic biomarkers in biofluids

Stalmach, A., Husi, H., Mosbahi, K., Albalat, A., Mullen, W. & Mischak, H., 2015, In : Methods in Molecular Biology. 1243, p. 187-205 19 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Molecular determinants of acute kidney injury

Husi, H. & Human, C., 1 Jul 2015, In : Journal of Injury and Violence Research. 7, 2, p. 75-86 12 p.

Research output: Contribution to journalArticle

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

Glorieux, G., Mullen, W., Duranton, F., Filip, S., Gayrard, N., Husi, H., Schepers, E., Neirynck, N., Schanstra, J. P., Jankowski, J., Mischak, H., Argilés, À., Vanholder, R., Vlahou, A. & Klein, J., 1 Nov 2015, In : Nephrology Dialysis Transplantation. 30, 11, p. 1842-1852 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Programmed cell death 6 interacting protein (PDCD6IP) and Rabenosyn-5 (ZFYVE20) are potential urinary biomarkers for upper gastrointestinal cancer

Husi, H., Skipworth, R. J. E., Cronshaw, A., Stephens, N. A., Wackerhage, H., Greig, C., Fearon, K. C. H. & Ross, J. A., 1 Jun 2015, In : Proteomics Clinical Applications. 9, 5-6, p. 586-596 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Protein interactome of muscle invasive bladder cancer

Bhat, A., Heinzel, A., Mayer, B., Perco, P., Mühlberger, I., Husi, H., Merseburger, A. S., Zoidakis, J., Vlahou, A., Schanstra, J. P., Mischak, H. & Jankowski, V., 1 Jan 2015, In : PLoS ONE. 10, 1

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease

Nkuipou-Kenfack, E., Duranton, F., Gayrard, N., Argilés, À., Lundin, U., Weinberger, K. M., Dakna, M., Delles, C., Mullen, W., Husi, H., Klein, J., Koeck, T., Zürbig, P. & Mischak, H., 2014, In : PLoS ONE. 9, 5, p. e96955

Research output: Contribution to journalArticle

67 Citations (Scopus)

Capillary electrophoresis interfaced with a mass spectrometer (CE-MS): technical considerations and applicability for biomarker studies in animals

Albalat, A., Husi, H., Siwy, J., Nally, J. E., McLaughlin, M., Eckersall, P. D. & Mullen, W., 2014, In : Current Protein and Peptide Science. 15, 1, p. 23-35 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Classical MALDI-MS versus CE-based ESI-MS proteomic profiling in urine for clinical applications

Albalat, A., Husi, H., Stalmach, A., Schanstra, J. P. & Mischak, H., 1 Jan 2014, In : Bioanalysis. 6, 2, p. 247-266 18 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Current advances in systems and integrative biology

Robinson, S. W., Fernandes, M. & Husi, H., 1 Aug 2014, In : Computational and Structural Biotechnology Journal. 11, 18, p. 35-46 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Discovery and validation of urinary biomarkers for detection of renal cell carcinoma

Frantzi, M., Metzger, J., Banks, R. E., Husi, H., Klein, J., Dakna, M., Mullen, W., Cartledge, J. J., Schanstra, J. P., Brand, K., Kuczyk, M. A., Mischak, H., Vlahou, A., Theodorescu, D. & Merseburger, A. S., 1 Feb 2014, In : Journal of Proteomics. 98C, p. 44-58 15 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Identification of urinary peptide biomarkers associated with rheumatoid arthritis

Stalmach, A., Johnsson, H., McInnes, I. B., Husi, H., Klein, J., Dakna, M., Mullen, W., Mischak, H. & Porter, D., 2014, In : PLoS ONE. 9, 8

Research output: Contribution to journalArticle

22 Citations (Scopus)

Increased sputum endotoxin levels are associated with an impaired lung function response to oral steroids in asthmatic patients

McSharry, C., Spears, M., Chaudhuri, R., Cameron, E. J., Husi, H. & Thomson, N. C., 1 Nov 2014, In : Journal of Allergy and Clinical Immunology. 134, 5, p. 1068-1075 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease

Husi, H., Agtmael, T. V., Mullen, W., Bahlmann, F. H., Schanstra, J. P., Vlahou, A., Delles, C., Perco, P. & Mischak, H., 1 Apr 2014, In : Circulation: Cardiovascular Genetics. 7, 2, p. 161-170 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Proteomics

Husi, H. & Albalat, A., 2014, Handbook of Pharmacogenomics and Stratified Medicine. Padmanabhan, S. (ed.). Academic Press, p. 147-179 33 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution