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  • P D Whitfield
2020

Lipidomics analysis of juveniles' blue mussels (Mytilus edulis L. 1758), a key economic and ecological species

Laudicella, V. A., Beveridge, C., Carboni, S., Franco, S. C., Doherty, M. K., Long, N., Mitchell, E., Stanley, M. S., Whitfield, P. D. & Hughes, A. D., 21 Feb 2020, In : PLoS ONE. 15, 2, e0223031.

Research output: Contribution to journalArticle

Open Access
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28 Downloads (Pure)
2019

Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids

Dorgau, B., Felemban, M., Hilgen, G., Kiening, M., Zerti, D., Hunt, N. C., Doherty, M., Whitfield, P., Hallam, D., White, K., Ding, Y., Krasnogor, N., Al-aama, J., Asfour, H. Z., Sernagor, E. & Lako, M., Apr 2019, In : Biomaterials. 199, p. 63-75 13 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
168 Downloads (Pure)

EMSY expression affects multiple components of skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., Mcgrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., 31 May 2019, In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
43 Downloads (Pure)

Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism

Ballard, E., Weber, J., Melchers, W. J. G., Tammireddy, S., Whitfield, P. D., Brakhage, A. A., Brown, A. J. P., Verweij, P. E. & Warris, A., 1 Sep 2019, In : Fungal Genetics and Biology. 130, p. 98-106 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
44 Downloads (Pure)
2018

Acute stress alters the rates of degradation of cardiac muscle proteins

Geary, B., Magee, K., Cash, P., Husi, H., Young, I. S., Whitfield, P. D. & Doherty, M. K., 22 Mar 2018, In : Journal of Proteomics. 7 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
10 Downloads (Pure)

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

Boyapati, R. K., Dorward, D. A., Tamborska, A., Kalla, R., Ventham, N. T., Doherty, M. K., Whitfield, P. D., Gray, M., Loane, J., Rossi, A. G., Satsangi, J. & Ho, G., 1 May 2018, In : Inflammatory Bowel Diseases. 24, 10, p. 2113-2122 9 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
33 Downloads (Pure)

Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-haberle, I., Murphy, M. P., Moult, P. R. & Cobley, J. N., 20 Mar 2018, In : Redox Biology. 16, p. 344-351 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
198 Downloads (Pure)

The glycine lipids of Bacteroides thetaiotaomicron are important for fitness during growth in vivo and in vitro

Lynch, A., Tammireddy, S. R., Doherty, M. K., Whitfield, P. D. & Clarke, D. J., 26 Oct 2018, In : Applied and Environmental Microbiology.

Research output: Contribution to journalArticle

Open Access
File
79 Downloads (Pure)
2017

Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

Morrice, N., Mcilroy, G. D., Tammireddy, S. R., Reekie, J., Shearer, K. D., Doherty, M. K., Delibegovi??, M., Whitfield, P. D. & Mody, N., 3 Mar 2017, In : Scientific Reports. 7, 43782 .

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
69 Downloads (Pure)

Lipid remodelling and an altered membrane proteome may drive the effects of EPA and DHA treatment on skeletal muscle glucose uptake and protein accretion

Jeromson, S., Mackenzie, I., Doherty, M. K., Whitfield, P. D., Bell, G., Dick, J., Shaw, A., Rao, F., Ashcroft, S., Philp, A., Galloway, S., Gallagher, I. J. & Hamilton, D. L., 27 Jun 2017, In : American Journal of Physiology - Endocrinology And Metabolism. ajpendo.00438.2015.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
20 Downloads (Pure)

Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE -/- mouse model of atherosclerosis with alterations in IL10/AMPKα pathway

Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Ziegler, K., Whitfield, P., Mody, N., Wilson, H. M. & Delibegovic, M., 13 Jun 2017, In : Molecular Metabolism.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
126 Downloads (Pure)

Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome

Dorward, D. A., Lucas, C. D., Doherty, M. K., Chapman, G. B., Scholefield, E. J., Conway Morris, A., Felton, J. M., Kipari, T., Humphries, D. C., Robb, C. T., Simpson, A. J., Whitfield, P. D., Haslett, C., Dhaliwal, K. & Rossi, A. G., 3 May 2017, In : Thorax. p. thoraxjnl-2017-210030

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
36 Downloads (Pure)
2016

Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson Disease

Magalhaes, J., Gegg, M. E., Migdalska-richards, A., Doherty, M. K., Whitfield, P. D. & Schapira, A. H. V., 15 Aug 2016, In : Human Molecular Genetics.

Research output: Contribution to journalArticle

Open Access
File
66 Citations (Scopus)
76 Downloads (Pure)

Comparing Simplification Strategies for the Skeletal Muscle Proteome

Geary, B., Young, I., Cash, P., Doherty, M. & Whitfield, P., 2 Mar 2016, In : Proteomes. 4, 1, p. 10

Research output: Contribution to journalArticle

Open Access
File
68 Downloads (Pure)

Determining synthesis rates of individual proteins in zebrafish (Danio rerio) with low levels of a stable isotope labelled amino acid

Geary, B., Magee, K., Cash, P., Young, I. S., Doherty, M. K. & Whitfield, P., 5 Apr 2016, In : Proteomics. 16, 9, p. 1398–1406 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
180 Downloads (Pure)

Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue

Mcilroy, G. D., Tammireddy, S. R., Maskrey, B. H., Grant, L., Doherty, M. K., Whitfield, P., Watson, D. G., Delibegović, M. & Mody, N., 15 Jan 2016, In : Biochemical Pharmacology. 100, p. 86-97 11 p.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Lipids and cardiovascular disease: where does dietary intervention sit alongside statin therapy?

Megson, I., Zabetakis, I. & Whitfield, P. D., 18 Apr 2016, In : Food Funct..

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
27 Downloads (Pure)

Neuronal human BACE1 knockin induces systemic diabetes in mice

Pluci??ska, K., Dekeryte, R., Koss, D., Shearer, K., Mody, N., Whitfield, P. D., Doherty, M. K., Mingarelli, M., Welch, A., Riedel, G., Delibegovic, M., Platt, B. & Whitfield, P., 2 May 2016, In : Diabetologia.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
197 Downloads (Pure)

Tuning the Nitric Oxide Release from CPO-27 MOFs

Cattaneo, D., Warrender, S. J., Duncan, M. J., Kelsall, C. J., Doherty, M. K., Whitfield, P., Megson, I. & Morris, R., 26 Jan 2016, In : RSC Adv.. 17, 6, p. 14059-14067 8 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
91 Downloads (Pure)
2014

12-hydroxyeicosatetraenoic acid is associated with variability in aspirin-induced platelet inhibition

Maskrey, B. H., Rushworth, G. F., Law, M. H., Treweeke, A. T., Wei, J., Leslie, S. J., Megson, I. L. & Whitfield, P. D., 23 Oct 2014, In : Journal of Inflammation (London, England). 11, 1, p. 33

Research output: Contribution to journalArticle

6 Citations (Scopus)
2013

Assessment of global proteome dynamics in carp - A Model for Investigating Environmental Stress

Doherty, M. K., Owen, M. A. G., Davies, S. J., Young, I. S. & Whitfield, P., 4 Oct 2013, In : Journal of Proteome Research.

Research output: Contribution to journalArticle

4 Citations (Scopus)
35 Citations (Scopus)
2012

A proteomics strategy for determining the synthesis and degradation rates of individual proteins in fish

Doherty, M. K., Brownridge, P., Owen, M. A. G., Davies, S. J., Young, I. S. & Whitfield, P., 2012, In : Journal of Proteomics. 75, 14, p. 4471-7 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The biology of nematode- and IL4R¿-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics

Thomas, G. D., Rückerl, D., Maskrey, B. H., Blaxter, M. L., Allen, J. E. & Whitfield, P., 13 Dec 2012, In : Blood. 120, 25, p. e93-e104

Research output: Contribution to journalArticle

33 Citations (Scopus)
2011

Alterations of primary fatty acid amides in serum of patients with severe mental illness

Schwarz, E., Whitfield, P., Nahnsen, S., Wang, L., Major, H., Leweke, F. M., Koethe, D., Lio, P. & Bahn, S., 2011, In : Frontiers in Bioscience (Elite Edition). 3, p. 308-14 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Mechanisms of resolution of inflammation: a focus on cardiovascular disease

Maskrey, B. H., Megson, I. L., Whitfield, P. & Rossi, A. G., 2011, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 5, p. 1001-6 6 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Proteomics moves from expression to turnover: update and future perspective

Doherty, M. K. & Whitfield, P., 2011, In : Expert Review of Proteomics. 8, 3, p. 325-34 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)