Research output per year
Research output per year
Project Details
Description
Specific types of T-cells are able to recognise portions of proteins displayed by melanoma cells, which illicits an immune response, leading to the destruction of tumour cells. Identification of the T-cells and the peptides they recognise increases our understanding of what types of features lead to an effective immune response capable of clearing tumours.
| Status | Active |
|---|---|
| Effective start/end date | 1/08/17 → … |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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Research output
- 6 Article
-
Prolonged stable disease in a uveal melanoma patient with germline MBD4 nonsense mutation treated with pembrolizumab and ipilimumab
Johansson, P. A., Stark, A., Palmer, J. M., Bigby, K., Brooks, K., Rolfe, O., Pritchard, A. L., Whitehead, K., Warrier, S., Glasson, W. & Hayward, N. K., 1 May 2019, In: Immunogenetics. 71, 5-6, p. 433-436 4 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
Identifying neoantigens for use in immunotherapy
Hutchison, S. & Pritchard, A. L., 24 Aug 2018, (E-pub ahead of print) In: Mammalian Genome. p. 1-17 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)187 Downloads (Pure) -
Targeting Neoantigens for Personalised Immunotherapy
Pritchard, A. L., 1 Apr 2018, In: BioDrugs. 32, 2, p. 99-109 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)39 Downloads (Pure)