Research output per year
Research output per year
Project Details
Description
Genomic changes within tumours can help to drive the tumourigenic process. These alterations can be identified using next generation sequencing approaches and the effects of these changes are assessed using in vitro functional models.
| Status | Active |
|---|---|
| Effective start/end date | 1/08/17 → … |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Pan-cancer analysis of whole genomes
Pritchard, A., 5 Feb 2020, In: Nature. 578, 7793, p. 82-93 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile729 Citations (Scopus)7 Downloads (Pure) -
Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours
Johansson, P. A., Brooks, K., Newell, F., Palmer, J. M., Wilmott, J. S., Pritchard, A. L., Broit, N., Wood, S., Carlino, M. S., Leonard, C., Koufariotis, L. T., Nathan, V., Beasley, A. B., Howlie, M., Dawson, R., Rizos, H., Schmidt, C. W., Long, G. V., Hamilton, H., Kiilgaard, J. F., & 15 others, 15 May 2020, In: Nature Communications. 11, p. 1-8 8 p., 2408 (2020).Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Citations (Scopus)36 Downloads (Pure) -
Prolonged stable disease in a uveal melanoma patient with germline MBD4 nonsense mutation treated with pembrolizumab and ipilimumab
Johansson, P. A., Stark, A., Palmer, J. M., Bigby, K., Brooks, K., Rolfe, O., Pritchard, A. L., Whitehead, K., Warrier, S., Glasson, W. & Hayward, N. K., 1 May 2019, In: Immunogenetics. 71, 5-6, p. 433-436 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus)