• 2028 Citations
  • 20 h-Index
19992020

Research output per year

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Research Output

  • 2028 Citations
  • 20 h-Index
  • 47 Article
  • 1 Commissioned report
  • 1 Review article
  • 1 Other contribution
2020

A proteomic signature for CNS adaptations to the valence of environmental stimulation

Shaw, A., Arnold, L. D., Privitera, L., Whitfield, P. D., Doherty, M. K. & Morè, L., 6 Apr 2020, In : Behavioural Brain Research. 383, p. 112515 112515.

Research output: Contribution to journalArticle

Lipidomics analysis of juveniles' blue mussels (Mytilus edulis L. 1758), a key economic and ecological species

Laudicella, V. A., Beveridge, C., Carboni, S., Franco, S. C., Doherty, M. K., Long, N., Mitchell, E., Stanley, M. S., Whitfield, P. D. & Hughes, A. D., 21 Feb 2020, In : PLoS ONE. 15, 2, e0223031.

Research output: Contribution to journalArticle

Open Access
File
39 Downloads (Pure)

Plasma proteome profiling of freshwater and seawater life stages of rainbow trout (Oncorhynchus mykiss)

Morro, B., Doherty, M. K., Balseiro, P., Handeland, S. O., Mackenzie, S., Sveier, H., Albalat, A. & Meador, J. P. (ed.), 3 Jan 2020, In : PLoS ONE. 15, 1, p. e0227003 e0227003.

Research output: Contribution to journalArticle

Open Access
File
24 Downloads (Pure)
2019

Application of lipidomics in bivalve aquaculture, a review

Laudicella, V. A., Whitfield, P. D., Carboni, S., Doherty, M. K. & Hughes, A. D., 13 Apr 2019, In : Reviews in Aquaculture. 25 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
3 Downloads (Pure)

Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids

Dorgau, B., Felemban, M., Hilgen, G., Kiening, M., Zerti, D., Hunt, N. C., Doherty, M., Whitfield, P., Hallam, D., White, K., Ding, Y., Krasnogor, N., Al-aama, J., Asfour, H. Z., Sernagor, E. & Lako, M., Apr 2019, In : Biomaterials. 199, p. 63-75 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
182 Downloads (Pure)
2018

Acute stress alters the rates of degradation of cardiac muscle proteins

Geary, B., Magee, K., Cash, P., Husi, H., Young, I. S., Whitfield, P. D. & Doherty, M. K., 22 Mar 2018, In : Journal of Proteomics. 7 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
10 Downloads (Pure)

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

Boyapati, R. K., Dorward, D. A., Tamborska, A., Kalla, R., Ventham, N. T., Doherty, M. K., Whitfield, P. D., Gray, M., Loane, J., Rossi, A. G., Satsangi, J. & Ho, G., 1 May 2018, In : Inflammatory Bowel Diseases. 24, 10, p. 2113-2122 9 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
34 Downloads (Pure)

Tapping all our Talents 2018

Yellowlees, L., Arnold, P., Bell Burnell, J., Brown, A., Doherty, M. & Colquhoun, A., 12 Nov 2018, Edinburgh: The Royal Society of Edinburgh. 108 p.

Research output: Book/ReportCommissioned report

Open Access
File
79 Downloads (Pure)

The glycine lipids of Bacteroides thetaiotaomicron are important for fitness during growth in vivo and in vitro

Lynch, A., Tammireddy, S. R., Doherty, M. K., Whitfield, P. D. & Clarke, D. J., 26 Oct 2018, In : Applied and Environmental Microbiology.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
80 Downloads (Pure)
2017

Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods

Edmonds, M. J., Geary, B., Doherty, M. K. & Morgan, A., 12 Jun 2017, In : Scientific Reports. 7, 1, 3299.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
24 Downloads (Pure)

Comparative proteome and peptidome analysis of the cephalic fluid secreted by Arapaima gigas (Teleostei Osteoglossidae) during and outside parental care

Torati, L. S., Migaud, H., Doherty, M. K., Siwy, J., Mullen, W., Mesquita, P. E. C. & Albalat, A., 24 Oct 2017, In : PLoS ONE. 12, 10, e0186692.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
136 Downloads (Pure)

Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

Morrice, N., Mcilroy, G. D., Tammireddy, S. R., Reekie, J., Shearer, K. D., Doherty, M. K., Delibegovi??, M., Whitfield, P. D. & Mody, N., 3 Mar 2017, In : Scientific Reports. 7, 43782 .

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
70 Downloads (Pure)

Expert Database for Outstanding Women in Academia

Doherty, M., 2017

Research output: Other contribution

Lipid remodelling and an altered membrane proteome may drive the effects of EPA and DHA treatment on skeletal muscle glucose uptake and protein accretion

Jeromson, S., Mackenzie, I., Doherty, M. K., Whitfield, P. D., Bell, G., Dick, J., Shaw, A., Rao, F., Ashcroft, S., Philp, A., Galloway, S., Gallagher, I. J. & Hamilton, D. L., 27 Jun 2017, In : American Journal of Physiology - Endocrinology And Metabolism. ajpendo.00438.2015.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
20 Downloads (Pure)

Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome

Dorward, D. A., Lucas, C. D., Doherty, M. K., Chapman, G. B., Scholefield, E. J., Conway Morris, A., Felton, J. M., Kipari, T., Humphries, D. C., Robb, C. T., Simpson, A. J., Whitfield, P. D., Haslett, C., Dhaliwal, K. & Rossi, A. G., 3 May 2017, In : Thorax. p. thoraxjnl-2017-210030

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
36 Downloads (Pure)
2016

Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson Disease

Magalhaes, J., Gegg, M. E., Migdalska-richards, A., Doherty, M. K., Whitfield, P. D. & Schapira, A. H. V., 15 Aug 2016, In : Human Molecular Genetics.

Research output: Contribution to journalArticle

Open Access
File
66 Citations (Scopus)
81 Downloads (Pure)

Comparing Simplification Strategies for the Skeletal Muscle Proteome

Geary, B., Young, I., Cash, P., Doherty, M. & Whitfield, P., 2 Mar 2016, In : Proteomes. 4, 1, p. 10

Research output: Contribution to journalArticle

Open Access
File
68 Downloads (Pure)

Determining synthesis rates of individual proteins in zebrafish (Danio rerio) with low levels of a stable isotope labelled amino acid

Geary, B., Magee, K., Cash, P., Young, I. S., Doherty, M. K. & Whitfield, P., 5 Apr 2016, In : Proteomics. 16, 9, p. 1398–1406 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
180 Downloads (Pure)

Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue

Mcilroy, G. D., Tammireddy, S. R., Maskrey, B. H., Grant, L., Doherty, M. K., Whitfield, P., Watson, D. G., Delibegović, M. & Mody, N., 15 Jan 2016, In : Biochemical Pharmacology. 100, p. 86-97 11 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Neuronal human BACE1 knockin induces systemic diabetes in mice

Pluci??ska, K., Dekeryte, R., Koss, D., Shearer, K., Mody, N., Whitfield, P. D., Doherty, M. K., Mingarelli, M., Welch, A., Riedel, G., Delibegovic, M., Platt, B. & Whitfield, P., 2 May 2016, In : Diabetologia.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
197 Downloads (Pure)

Tuning the Nitric Oxide Release from CPO-27 MOFs

Cattaneo, D., Warrender, S. J., Duncan, M. J., Kelsall, C. J., Doherty, M. K., Whitfield, P., Megson, I. & Morris, R., 26 Jan 2016, In : RSC Adv.. 17, 6, p. 14059-14067 8 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
93 Downloads (Pure)
2014

Endothelial cell oxidative stress in diabetes: a key driver of cardiovascular complications?

Shaw, A., Doherty, M. K., Mutch, N. J., MacRury, S. M. & Megson, I. L., 1 Aug 2014, In : Biochemical Society Transactions. 42, 4, p. 928-33 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2013

Assessment of global proteome dynamics in carp - A Model for Investigating Environmental Stress

Doherty, M. K., Owen, M. A. G., Davies, S. J., Young, I. S. & Whitfield, P., 4 Oct 2013, In : Journal of Proteome Research.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2012

A proteomics strategy for determining the synthesis and degradation rates of individual proteins in fish

Doherty, M. K., Brownridge, P., Owen, M. A. G., Davies, S. J., Young, I. S. & Whitfield, P., 2012, In : Journal of Proteomics. 75, 14, p. 4471-7 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Search for schizophrenia susceptibility variants at the HLA-DRB1 locus among a British population

Halley, L., Doherty, M. K., Megson, I. L., McNamara, N., Gadja, A. & Wei, J., 2012, In : Immunogenetics. 65, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2011

Proteomics moves from expression to turnover: update and future perspective

Doherty, M. K. & Whitfield, P., 2011, In : Expert Review of Proteomics. 8, 3, p. 325-34 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2010

Degradative proteomics and disease mechanisms

Lanucara, F., Brownridge, P., Young, I. S., Whitfield, P. & Doherty, M. K., 2010, In : Proteomics. Clinical Applications. 4, 2, p. 133-42 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Evidence for an interaction between Golli and STIM1 in store-operated calcium entry

Walsh, C. M., Doherty, M. K., Tepikin, A. V. & Burgoyne, R. D., 15 Sep 2010, In : The Biochemical Journal. 430, 3, p. 453-60 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2009

Turnover of the human proteome - determination of protein intracellular stability by dynamic SILAC

Doherty, M. K., Hammond, D. E., Clague, M. J., Gaskell, S. J. & Beynon, R. J., Jan 2009, In : Journal of Proteome Research. 8, 1, p. 104-12 9 p.

Research output: Contribution to journalArticle

194 Citations (Scopus)
2008

A random mutagenesis approach to isolate dominant-negative yeast sec1 mutants reveals a functional role for domain 3a in yeast and mammalian Sec1/Munc18 proteins

Boyd, A., Ciufo, L. F., Barclay, J. W., Graham, M. E., Haynes, L. P., Doherty, M. K., Riesen, M., Burgoyne, R. D. & Morgan, A., Sep 2008, In : Genetics. 180, 1, p. 165-78 14 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Proteomics and naturally occurring animal diseases: Opportunities for animal and human medicine

Doherty, M. K., Beynon, R. J. & Whitfield, P., 2008, In : Proteomics. Clinical Applications. 2, 2, p. 135-41 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2007

Avian proteomics: advances, challenges and new technologies

Doherty, M. K., McLean, L. & Beynon, R. J., 2007, In : Cytogenetic and Genome Research. 117, 1-4, p. 358-369 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Biomarker discovery in animal health and disease: the application of post-genomic technologies

Moore, R. E., Kirwan, J., Doherty, M. K. & Whitfield, P., 2007, In : Biomarker Insights. 2, p. 185-96 12 p.

Research output: Contribution to journalArticle

Global cooling: cold acclimation and the expression of soluble proteins in carp skeletal muscle

McLean, L., Young, I. S., Doherty, M. K., Robertson, D. H. L., Cossins, A. R., Gracey, A. Y., Beynon, R. J. & Whitfield, P., 2007, In : Journal of Proteomics. 7, 15, p. 2667-81 15 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2006

Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery

McCullough, J., Row, P. E., Lorenzo, O., Doherty, M., Beynon, R., Clague, M. J. & Urbé, S., 24 Jan 2006, In : Current Biology : CB. 16, 2, p. 160-5 6 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)

Multiplexed absolute quantification for proteomics using concatenated signature peptides encoded by QconCAT genes

Pratt, J. M., Simpson, D. M., Doherty, M. K., Rivers, J., Gaskell, S. J. & Beynon, R. J., 2006, In : Nature Protocols. 1, 2, p. 1029-1043 15 p.

Research output: Contribution to journalArticle

274 Citations (Scopus)

Protein turnover on the scale of the proteome

Doherty, M. K. & Beynon, R. J., Feb 2006, In : Expert Review of Proteomics. 3, 1, p. 97-110 14 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2005

Multiplexed absolute quantification in proteomics using artificial QCAT proteins of concatenated signature peptides

Beynon, R. J., Doherty, M. K., Pratt, J. M. & Gaskell, S. J., Aug 2005, In : Nature Methods. 2, 8, p. 587-9 3 p.

Research output: Contribution to journalArticle

353 Citations (Scopus)

Proteome dynamics in complex organisms: using stable isotopes to monitor individual protein turnover rates

Doherty, M. K., Whitehead, C., McCormack, H., Gaskell, S. J. & Beynon, R. J., Feb 2005, In : Journal of Proteomics. 5, 2, p. 522-33 12 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

The subunit structure and dynamics of the 20S proteasome in chicken skeletal muscle

Hayter, J. R., Doherty, M. K., Whitehead, C., McCormack, H., Gaskell, S. J. & Beynon, R. J., Sep 2005, In : Molecular & Cellular Proteomics : MCP. 4, 9, p. 1370-81 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2004

A proteome analysis of the subcutaneous gel in avian hatchlings

McLean, L., Doherty, M. K., Deeming, D. C. & Beynon, R. J., Mar 2004, In : Molecular & Cellular Proteomics : MCP. 3, 3, p. 250-6 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation

Mowat, C. G., Rothery, E., Miles, C. S., McIver, L., Doherty, M. K., Drewette, K., Taylor, P., Walkinshaw, M. D., Chapman, S. K. & Reid, G. A., Oct 2004, In : Nature Structural & Molecular Biology. 11, 10, p. 1023-1024 2 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Protein turnover in chicken skeletal muscle: understanding protein dynamics on a proteome-wide scale

Doherty, M. K., McClean, L., Edwards, I., McCormack, H., McTeir, L., Whitehead, C., Gaskell, S. J. & Beynon, R. J., Apr 2004, In : British Poultry Science. 45 Suppl 1, p. S27-8

Research output: Contribution to journalArticle

8 Citations (Scopus)

The nature of the subcutaneous gel in chick hatchlings: a proteomics approach

McLean, L., Doherty, M. K., Deeming, D. C. & Beynon, R. J., Apr 2004, In : British Poultry Science. 45 Suppl 1, p. S37 1 p.

Research output: Contribution to journalArticle

The proteome of chicken skeletal muscle: changes in soluble protein expression during growth in a layer strain

Doherty, M. K., McLean, L., Hayter, J. R., Pratt, J. M., Robertson, D. H. L., El-Shafei, A., Gaskell, S. J. & Beynon, R. J., Jul 2004, In : Journal of Proteomics. 4, 7, p. 2082-93 12 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
2003

The kinetic mechanism of phosphomevalonate kinase

Pilloff, D., Dabovic, K., Romanowski, M. J., Bonanno, J. B., Doherty, M., Burley, S. K. & Leyh, T. S., 14 Feb 2003, In : The Journal of Biological Chemistry. 278, 7, p. 4510-5 6 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2001

Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase

Mowat, C. G., Moysey, R., Miles, C. S., Leys, D., Doherty, M. K., Taylor, P., Walkinshaw, M. D., Reid, G. A. & Chapman, S. K., 16 Oct 2001, In : Analytical Biochemistry. 40, 41, p. 12292-8 7 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2000

Identification of the active site acid/base catalyst in a bacterial fumarate reductase: a kinetic and crystallographic study

Doherty, M. K., Pealing, S. L., Miles, C. S., Moysey, R., Taylor, P., Walkinshaw, M. D., Reid, G. A. & Chapman, S. K., 5 Sep 2000, In : Analytical Biochemistry. 39, 35, p. 10695-10701 7 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
1999

Flavocytochromes: transceivers and relays in biological electron transfer

Chapman, S. K., Welsh, F., Moysey, R., Mowat, C., Doherty, M. K., Turner, K. L., Munro, A. W. & Reid, G. A., Feb 1999, In : Biochemical Society Transactions. 27, 2, p. 185-9 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Redox properties of flavocytochrome c3 from Shewanella frigidimarina NCIMB400

Turner, K. L., Doherty, M. K., Heering, H. A., Armstrong, F. A., Reid, G. A. & Chapman, S. K., 16 Mar 1999, In : Analytical Biochemistry. 38, 11, p. 3302-9 8 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)