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James Cobley

Doctor

  • IV2 3JH

    United Kingdom

Accepting PhD Students

  • 710 Citations
  • 16 h-Index
20132020

Research output per year

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Personal profile

Research expertise

  • Redox biochemistry
  • Mitochondrial reactive oxygen species
  • Synapse pruning
  • Microfluidics
  • Exercise

Research expertise

I am a redox biochemistry researcher with a particular interest in how the production and metabolism of mitochondrial reactive oxygen species like superoxide and hydrogen peroxide impact development. 

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Projects

Does polyphenol supplementation suppress the increase in oxidative stress and inflammation caused by reduced physical activity?

Crabtree, D., Megson, I., Hickson, K., Cobley, J., Goszcz, K., Muggeridge, D. & Gorely, T.

24/04/18 → 1/06/20

Project: Research

Research Output

  • 710 Citations
  • 16 h-Index
  • 13 Article
  • 2 Review article

Catalyst-free Click PEGylation reveals substantial mitochondrial ATP synthase sub-unit alpha oxidation before and after fertilisation

Cobley, J., Husi, H. & Jimenez Fernandez, E., 18 Jun 2019, In : Redox Biology. 26, p. 1-8 8 p., 101258.

Research output: Contribution to journal › Article

Open Access
File
    • 3 Citations (Scopus)
    36 Downloads (Pure)

    Proteomic strategies to unravel age-related redox signalling defects in skeletal muscle

    Cobley, J. N., Sakellariou, G. K., Husi, H. & McDonagh, B., 20 Feb 2019, In : Free Radical Biology & Medicine. 132, p. 24-32 9 p.

    Research output: Contribution to journal › Review article

    Open Access
    File
    • 5 Citations (Scopus)
    6 Downloads (Pure)

    13 reasons why the brain is susceptible to oxidative stress

    Cobley, J. & Bailey, D., 31 May 2018, In : Redox Biology. 15, p. 490-503 15 p.

    Research output: Contribution to journal › Review article

    Open Access
    File
    • 127 Citations (Scopus)
    255 Downloads (Pure)

    Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

    Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-haberle, I., Murphy, M. P., Moult, P. R. & Cobley, J. N., 20 Mar 2018, In : Redox Biology. 16, p. 344-351 8 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 10 Citations (Scopus)
    206 Downloads (Pure)

    To clot or not to clot? That is a free radical question

    Crabtree, D. R., Muggeridge, D., Leslie, S. J., Megson, I. L. & Cobley, J. N., 9 Sep 2018, In : Journal of Physiology. 596, 20, p. 4805-4806 2 p.

    Research output: Contribution to journal › Article

    Open Access
    File