Projects per year
Personal profile
Research Expertise
- Redox biochemistry
- Mitochondrial reactive oxygen species
- Synapse pruning
- Microfluidics
- Exercise
Research Expertise
I am a redox biochemistry researcher with a particular interest in how the production and metabolism of mitochondrial reactive oxygen species like superoxide and hydrogen peroxide impact development.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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The effect of physical activity on appetite control and free-living energy intake in older adults: A pilot study.
Crabtree, D. R., Hickson, K., Cobley, J., Husi, H., Stalmach, A. & Holliday, A.
12/09/22 → …
Project: Research
File -
Does polyphenol supplementation suppress the increase in oxidative stress and inflammation caused by reduced physical activity?
Crabtree, D. R., Megson, I., Hickson, K., Cobley, J., Goszcz, K., Muggeridge, D. & Gorely, T.
24/04/18 → …
Project: Research
File -
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Influence of complex I mediated superoxide production on fertility: Implications for in vitro fertilisation
3/09/19 → 2/03/21
Project: Research
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Oxiforms: Unique cysteine residue- and chemotype-specified chemical combinations can produce functionally-distinct proteoforms
Cobley, J. N., 5 May 2023, (E-pub ahead of print) In: BioEssays : news and reviews in molecular, cellular and developmental biology. 45, 7, p. e2200248Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Performance benchmarking microplate-immunoassays for quantifying target-specific cysteine oxidation reveals their potential for understanding redox-regulation and oxidative stress
Tuncay, A., Crabtree, D. R., Muggeridge, D. J., Husi, H. & Cobley, J. N., 14 May 2023, In: Free Radical Biology & Medicine. 204, p. 252-265Research output: Contribution to journal › Article › peer-review
Open Access -
Exercise decreases PP2A-specific reversible thiol oxidation in human erythrocytes: Implications for redox biomarkers
Muggeridge, D., Crabtree, D. R., Tuncay, A., Megson, I., Davison, G. W. & Cobley, J., 30 Mar 2022, In: Free Radical Biology & Medicine. 182, p. 73-78 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)1 Downloads (Pure) -
RedoxiFluor: A microplate technique to quantify target-specific protein thiol redox state in relative percentage and molar terms
Tuncay, A., Noble, A., Guille, M. & Cobley, J. N., 1 Mar 2022, In: Free Radical Biology & Medicine. 181, p. 118-129Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Immunological Techniques to Assess Protein Thiol Redox State: Opportunities, Challenges and Solutions
Cobley, J. N. & Husi, H., 15 Apr 2020, In: Antioxidants. 9, 4Research output: Contribution to journal › Review article › peer-review
Open AccessFile15 Citations (Scopus)30 Downloads (Pure) -
Mechanisms of Mitochondrial ROS Production in Assisted Reproduction: The Known, the Unknown, and the Intriguing
Cobley, J. N., 29 Sept 2020, In: Antioxidants. 9, 10, 31 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile23 Citations (Scopus)26 Downloads (Pure) -
OP2 Prophylactic, N-Acetylcysteine unsuccessful in influencing plasma antioxidant capacity in a parallel-group randomized controlled trial of patients with chronic kidney disease stage III; implications for contrast induced nephropathy
Raja, KI., Hickson, K., Treweeke, AT., Rushworth, G., Morrison, E., Sandilands, E., Cobley, JN., McEneaney, D., Eddleston, M. & Megson, IL., 5 Apr 2020, p. A1.Research output: Contribution to conference › Paper › peer-review