Projects per year
Personal profile
Research Expertise
- Redox biochemistry
- Mitochondrial reactive oxygen species
- Synapse pruning
- Microfluidics
- Exercise
Research Expertise
I am a redox biochemistry researcher with a particular interest in how the production and metabolism of mitochondrial reactive oxygen species like superoxide and hydrogen peroxide impact development.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The effect of physical activity on appetite control and free-living energy intake in older adults: A pilot study.
Crabtree, D. R., Hickson, K., Cobley, J., Husi, H., Stalmach, A. & Holliday, A.
12/09/22 → …
Project: Research
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Does polyphenol supplementation suppress the increase in oxidative stress and inflammation caused by reduced physical activity?
Crabtree, D. R., Megson, I., Hickson, K., Cobley, J., Goszcz, K., Muggeridge, D. & Gorely, T.
24/04/18 → …
Project: Research
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Influence of complex I mediated superoxide production on fertility: Implications for in vitro fertilisation
3/09/19 → 2/03/21
Project: Research
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Exercise decreases PP2A-specific reversible thiol oxidation in human erythrocytes: Implications for redox biomarkers
Muggeridge, D., Crabtree, D. R., Tuncay, A., Megson, I., Davison, G. W. & Cobley, J., 30 Mar 2022, In: Free Radical Biology & Medicine. 182, p. 73-78 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Immunological Techniques to Assess Protein Thiol Redox State: Opportunities, Challenges and Solutions
Cobley, J. N. & Husi, H., 15 Apr 2020, In: Antioxidants. 9, 4Research output: Contribution to journal › Review article › peer-review
Open AccessFile13 Citations (Scopus)24 Downloads (Pure) -
Mechanisms of Mitochondrial ROS Production in Assisted Reproduction: The Known, the Unknown, and the Intriguing
Cobley, J. N., 29 Sep 2020, In: Antioxidants. 9, 10, 31 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile23 Citations (Scopus)23 Downloads (Pure) -
OP2 Prophylactic, N-Acetylcysteine unsuccessful in influencing plasma antioxidant capacity in a parallel-group randomized controlled trial of patients with chronic kidney disease stage III; implications for contrast induced nephropathy
Raja, KI., Hickson, K., Treweeke, AT., Rushworth, G., Morrison, E., Sandilands, E., Cobley, JN., McEneaney, D., Eddleston, M. & Megson, IL., 5 Apr 2020, p. A1.Research output: Contribution to conference › Paper › peer-review
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Oxidative stress and inflammation in the development of cardiovascular disease and contrast induced nephropathy
Cervantes-Gracia, K., Raja, K., Llanas-Cornejo, D., Cobley, J. N., Megson, I. L., Chahwan, R. & Husi, H., 1 Sep 2020, In: Vessel Plus. 4, 27, 19 p., 27.Research output: Contribution to journal › Review article › peer-review
Open AccessFile6 Citations (Scopus)21 Downloads (Pure) -
P0917n-acetyl cysteine fails to impact on plasma antioxidant capacity in both a placebo controlled crossover study and a parallel group trial of patients with ckd stage iii: implications for its use as a prophylactic for contrast induced nephropathy
Raja, K., Hickson, K., Treweeke, A., Rushworth, G., Morrison, E., Sandilands, E., Cobley, J., McEneaney, D., Eddleston, M. & Megson, I., 6 Jun 2020.Research output: Contribution to conference › Abstract
Open Access -
Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in Xenopus Laevis Oocytes
Cobley, J., Noble, A., Bessell, R., Guille, M. & Husi, H., 5 Mar 2020, In: Antioxidants. 9, 3Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)13 Downloads (Pure)