Projects per year
Personal profile
Research expertise
- Redox biochemistry
- Mitochondrial reactive oxygen species
- Synapse pruning
- Microfluidics
- Exercise
Research expertise
I am a redox biochemistry researcher with a particular interest in how the production and metabolism of mitochondrial reactive oxygen species like superoxide and hydrogen peroxide impact development.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Does polyphenol supplementation suppress the increase in oxidative stress and inflammation caused by reduced physical activity?
Crabtree, D. R., Megson, I., Hickson, K., Cobley, J., Goszcz, K., Muggeridge, D. & Gorely, T.
24/04/18 → …
Project: Research
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Influence of complex I mediated superoxide production on fertility: Implications for in vitro fertilisation
3/09/19 → 2/03/21
Project: Research
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Immunological Techniques to Assess Protein Thiol Redox State: Opportunities, Challenges and Solutions
Cobley, J. N. & Husi, H., 15 Apr 2020, In: Antioxidants. 9, 4Research output: Contribution to journal › Review article › peer-review
Open AccessFile12 Citations (Scopus)16 Downloads (Pure) -
Mechanisms of Mitochondrial ROS Production in Assisted Reproduction: The Known, the Unknown, and the Intriguing
Cobley, J. N., 29 Sep 2020, In: Antioxidants. 9, 10, 31 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile12 Citations (Scopus)12 Downloads (Pure) -
Oxidative stress and inflammation in the development of cardiovascular disease and contrast induced nephropathy
Cervantes-Gracia, K., Raja, K., Llanas-Cornejo, D., Cobley, J. N., Megson, I. L., Chahwan, R. & Husi, H., 1 Sep 2020, In: Vessel Plus. 4, 27, 19 p., 27.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Citations (Scopus)15 Downloads (Pure) -
Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in Xenopus Laevis Oocytes
Cobley, J., Noble, A., Bessell, R., Guille, M. & Husi, H., 5 Mar 2020, In: Antioxidants. 9, 3Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)8 Downloads (Pure) -
The mitochondria-targeted antioxidant MitoQ, attenuates exercise-induced mitochondrial DNA damage
Williamson, J., Hughes, C. M., Cobley, J. N. & Davison, G. W., 1 Sep 2020, In: Redox Biology. 36, 10 p., 101673.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)5 Downloads (Pure) -
Catalyst-free Click PEGylation reveals substantial mitochondrial ATP synthase sub-unit alpha oxidation before and after fertilisation
Cobley, J., Husi, H. & Jimenez Fernandez, E., 18 Jun 2019, (E-pub ahead of print) In: Redox Biology. 26, p. 1-8 8 p., 101258.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)79 Downloads (Pure) -
Proteomic strategies to unravel age-related redox signalling defects in skeletal muscle
Cobley, J. N., Sakellariou, G. K., Husi, H. & McDonagh, B., 20 Feb 2019, In: Free Radical Biology & Medicine. 132, p. 24-32 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile10 Citations (Scopus)43 Downloads (Pure)