Projects per year
Personal profile
Research expertise
As the Head of Health Research & Innovation at the University of the Highlands & Islands, I oversee the activities of the various research teams, with a particular remit to direct the activities of the members of the Division of Biomedical Sciences. As well as supervising my research team, I am responsible for the departmental budget and for management of those research grants for which I am designated principal investigator. I am also ultimately responsible for the health and safety of my team members. My role includes a remit to design and deliver the strategy for curriculum development and research for the School of Health at the university. I am also a Visiting Professor at Robert Gordon University.
The focus of my research is the role of nitric oxide in vascular disease and the potential benefits of nitric oxide donor drugs as vasodilators, anti-platelet agents and anti-inflammatory agents. My interests include the interaction of nitric oxide with oxidant species and establishment of the importance of this interaction in the atherosclerotic process that underlies heart disease. Through collaboration with Prof Adriano Rossi (Centre for Inflammation Research, University of Edinburgh), I have expanded my research profile to encompass the role of NO in inflammatory cell apoptosis and, via several other collaborations, the therapeutic potential of NO in diseases as diverse as fungal toenail infection and trypanosomiasis. Furthermore, I have been involved in projects relating to acute renal failure (principle investigator), organ transplant (principal investigator), pre-eclampsia, and the potential benefits of novel coatings to prevent thrombosis in medical devices. The focus of our current research is shifting towards preventative medicine: I have ongoing projects associated with the health benefits of polyphenols and exercise. Current research includes looking at why COVID-19 seems more severe in patients with diabetes and tracking of long-COVID symptoms to begin to identify the underlying mechanisms and inflammatory system responses.
My research output is reflected in consistent publication of original papers and reviews in internationally recognised journals; my current h-factor is 46 (Scopus), 53 (Google Scholar).
In recognition of my contribution to these areas of cardiovascular science and to education as a whole, I have been awarded Fellowships with the Pharmacological Society, the Royal Biological Society and the Higher Education Academy.
Education/Academic qualification
Doctor of Philosophy, University of St Andrews
Award Date: 1 Jan 1993
Bachelor of Science, University of St Andrews
Award Date: 1 Jan 1990
External positions
Member, Chief Scientist Office
Jun 2019 → …Member, UK Ressearch and Innovation Future Leaders Fellowship Peer Review College
20 Aug 2018 → …Associate Editor, Antioxidants
2018 → …Fellow, British Pharmacological Society
2017 → …Associate Editor
2014 → …Visiting Professor, Robert Gordon University
2013 → …Fellow
2012 → …Fellow
2007 → …Editorial Board
2006 → 2010Honorary Research Fellow, The University of Edinburgh
2006 → 2018Keywords
- QP Physiology
- Diabetes
- Cardiovascular
- REF 03
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Network
Projects
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Nanomaterials and photonic solutions: Novel ‘at source’ approaches to stop hospital-derived priority substances reaching the sewer network
Valdivia, M., Kean, A. & Megson, I.
1/10/20 → 30/09/24
Project: Other
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Does polyphenol supplementation suppress the increase in oxidative stress and inflammation caused by reduced physical activity?
Crabtree, D., Megson, I., Hickson, K., Cobley, J., Goszcz, K., Muggeridge, D. & Gorely, T.
24/04/18 → …
Project: Research
File -
(ECME) A cross-border proposal for a New Eastern Corridor Medical Engineering Centre
1/03/17 → 31/12/21
Project: Research
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1048IM: Inverness and Highland City-Region Deal
Megson, I., Giangreco, A. & MacRury, S.
1/01/17 → 31/07/27
Project: Other
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Evaluation of a chronic obstructive pulmonary disease self-management tool for NHS Highland
Megson, I., Sage, D. B. & Giangreco, A.
Project: Consultancy
Research output
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Measurement of Heart Rate using the Polar OH1® and Fitbit Charge 3® Wearable Devices in Healthy Adults during Light, Moderate, Vigorous and Sprint-Based Exercise: Validation Study
Muggeridge, D., Hickson, K., Davies, A., Giggins, O., Megson, I., Gorely, T. & Crabtree, D., 25 Mar 2021, In: JMIR mHealth and uHealth. 9, 3, p. 1-13 13 p., e25313.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System
Roberts, J., Pritchard, A. L., Treweeke, A. T., Rossi, A. G., Brace, N., Cahill, P., Macrury, S. M., Wei, J. & Megson, I. L., 3 Feb 2021, In: Frontiers in Cardiovascular Medicine. 7Research output: Contribution to journal › Review article › peer-review
Open AccessFile20 Downloads (Pure) -
Antibacterial efficacy from NO-releasing MOF–polymer films
Duncan, M., Wheatley, P., Coghill, E., Vornholt, S., Warrander, S., Megson, I. & Morris, R. E., 7 Oct 2020, In: Materials Advances. 1, p. 2509-2519 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Downloads (Pure) -
Oxidative stress and inflammation in the development of cardiovascular disease and contrast induced nephropathy
Cerventes-Gracia, K., Raja, K., Llanas-Cornejo, D., Cobley, J., Megson, I., Chahwan, R. & Husi, H., 1 Sep 2020, In: Vessel Plus. 4, 27, 19 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Downloads (Pure) -
Radial artery access site complications during cardiac procedures, clinical implications and potential solutions: The role of nitric oxide
Coghill, E., Johnson, T., Morris, R., Leslie, S. & Megson, I., 26 Jan 2020, In: World Journal of Cardiology. 12, 1, p. 26 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)8 Downloads (Pure) -
The impact of glucose exposure on bioenergetics and function in a cultured endothelial cell model and the implications for cardiovascular health in diabetes
Fiorello, M. L., Treweeke, A., Macfarlane, D. & Megson, I., 11 Nov 2020, In: Scientific Reports. 10, 19547.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
Co-ingestion of antioxidant drinks with an unhealthy challenge meal fails to prevent post-prandial endothelial dysfunction: an open-label, crossover study in healthy older adults
Goszcz, K., Megson, I., Muggeridge, D., Treweeke, A., Hickson, K. & Adamson, J., 7 Mar 2019.Research output: Contribution to conference › Abstract › peer-review
Open AccessFile50 Downloads (Pure)
Prizes
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SCDI Highlands and Islands Enterprise Award for Excellence in Research and Innovation
Megson, Ian (Recipient) & Giangreco, Adam (Recipient), Sep 2019
Prize: Prize (including medals and awards)
Activities
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Scottish Cardiovascular Forum 2019
Ian Megson (Organiser)
1 Feb 2019Activity: Participating in or organising an event › Organising a conference
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Scottish Cardiovascular Forum 2017
Ian Megson (Chair)
4 Feb 2017Activity: Participating in or organising an event › Participation in conference
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Masteclasses for S1/S2 science pupils
Ian Megson (Presenter)
6 May 2017 → 13 May 2017Activity: Other › Types of Public engagement and outreach - Schools engagement
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Departmental seminar
Ian Megson (Speaker)
3 Mar 2017Activity: Other › Types of External academic engagement - Invited talk
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Departmental seminar
Ian Megson (Speaker)
3 Aug 2017Activity: Other › Types of Public engagement and outreach - Public lecture/debate/seminar
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UHI Research Cluster meeting - Research-teaching linkages
Ian Megson (Member of programme committee)
13 Jun 2016 → 14 Jun 2016Activity: Participating in or organising an event › Participation in workshop, seminar, course
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Millburn Academy presentations
Ian Megson (Presenter)
24 Aug 2016Activity: Other › Types of Public engagement and outreach - Schools engagement
Press / Media
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Highland researchers at forefront of water quality innovation
29/10/20
1 item of Media coverage
Press/Media: Research
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New projects place Highland researchers at forefront of water innovation
29/10/20
1 item of Media coverage
Press/Media: Research
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University aims to develop system which removes pharmaceutical drugs from hospital wastewater
28/10/20
1 item of Media coverage
Press/Media: Research
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Nanotechnology professor appointed at university
18/07/19
1 item of Media coverage
Press/Media: Research
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Highland scientist's liver cancer therapy passes three years of clinical trials
10/05/19
1 item of Media coverage
Press/Media: Research
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Active Health Research at the University of the Highlands and Islands
Daniel Crabtree, Kirsty Hickson, David Muggeridge & Ian Megson
22/02/19
1 item of Media coverage
Press/Media: Other
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Media release: Inverness welcomes cardiovascular experts
4/02/19
1 item of Media coverage
Press/Media: Research