Ian Megson

Professor

  • IV2 3JH

    United Kingdom

  • United Kingdom

  • 7124 Citations
  • 43 h-Index
1992 …2020
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Personal profile

Research expertise

As the Head of Health Research & Innovation at the University of the Highlands & Islands, I oversee the activities of the various research teams, with a particular remit to direct the activities of the members of the Division of Biomedical Sciences. As well as supervising my research team, I am responsible for the departmental budget and for management of those research grants for which I am designated principal investigator. I am also ultimately responsible for the health and safety of my team members. My role includes a remit to design and deliver the strategy for curriculum development and research for the School of Health at the university. I am also a Visiting Professor at Robert Gordon University.

The focus of my research is the role of nitric oxide in vascular disease and the potential benefits of nitric oxide donor drugs as vasodilators, anti-platelet agents and anti-inflammatory agents. My interests include the interaction of nitric oxide with oxidant species and establishment of the importance of this interaction in the atherosclerotic process that underlies heart disease. Through collaboration with Prof Adriano Rossi (Centre for Inflammation Research, University of Edinburgh), I have expanded my research profile to encompass the role of NO in inflammatory cell apoptosis and, via several other collaborations, the therapeutic potential of NO in diseases as diverse as fungal toenail infection and trypanosomiasis. Furthermore, I have been involved in projects relating to acute renal failure (principle investigator), organ transplant (principal investigator), pre-eclampsia, and the potential benefits of novel coatings to prevent thrombosis in medical devices. The focus of our current research is shifting towards preventative medicine: I have ongoing collaborations with the James Hutton Institute and the Rowett Institute to establish the antioxidant capacity of soft berry extracts with a view to their health benefits in the cardiovascular impact of diabetes. My research output is reflected in consistent publication of original papers and reviews in internationally recognised journals.

In recognition of my contribution to these areas of cardiovascular science and to education as a whole, I have been awarded Fellowships with the Pharmacological Society, the Royal Biological Society and the Higher Educationm Academy.

LinkedIN profile

Researchgate profile

Education/Academic qualification

Doctor of Philosophy, University of St Andrews

Bachelor of Science, University of St Andrews

External positions

Member

Jun 2019 → …

Member, UK Ressearch and Innovation Future Leaders Fellowship Peer Review College

20 Aug 2018 → …

Associate Editor, Antioxidants

2018 → …

Fellow, British Pharmacological Society

2017 → …

Associate Editor

2014 → …

Visiting Professor

2013 → …

Fellow

2012 → …

Fellow

2007 → …

Editorial Board

20062010

Honorary Research Fellow

20062018

Keywords

  • QP Physiology
  • Diabetes
  • Cardiovascular

Fingerprint Dive into the research topics where Ian Megson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Nitric Oxide Medicine & Life Sciences
Nitric Oxide Donors Medicine & Life Sciences
S-Nitrosothiols Medicine & Life Sciences
Antioxidants Medicine & Life Sciences
Blood Platelets Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences
Glutathione Medicine & Life Sciences
Platelet Aggregation Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2011 2020

Research Output 1992 2019

  • 7124 Citations
  • 43 h-Index
  • 129 Article
  • 1 Abstract
  • 1 Meeting abstract
  • 1 Book/Film/Article review
35 Downloads (Pure)
Open Access
File
Cross-Over Studies
Meals
Eating
Antioxidants
Reactive Oxygen Species
3 Downloads (Pure)
Open Access
File
Cross-Over Studies
Meals
Volunteers
Eating
Antioxidants
16 Downloads (Pure)

Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease

Burtenshay, D., Kitching, M., Redmond, E., Megson, I. & Cahill, P., 2 Aug 2019, In : Frontiers in Cardiovascular Medicine. 6, 89.

Research output: Contribution to journalArticle

Open Access
File
Tunica Intima
Reactive Oxygen Species
Stem Cells
Blood Vessels
Niacinamide
6 Citations (Scopus)
196 Downloads (Pure)

Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-haberle, I., Murphy, M. P., Moult, P. R. & Cobley, J. N., 20 Mar 2018, In : Redox Biology. 16, p. 344-351 8 p.

Research output: Contribution to journalArticle

Open Access
File
Synapses
Reactive Oxygen Species
Neuromuscular Junction
Neurotoxins
Cues
31 Citations (Scopus)
43 Downloads (Pure)

Bioactive polyphenols and cardiovascular disease: chemical antagonists, pharmacological agents or xenobiotics that drive an adaptive response?

Goszcz, K., Duthie, G. G., Stewart, D., Leslie, S. J. & Megson, I. L., 10 Jan 2017, In : British Journal of Pharmacology.

Research output: Contribution to journalBook/Film/Article review

Open Access
File
Polyphenols
Xenobiotics
Cardiovascular Diseases
Antioxidants
Pharmacology

Activities 2012 2019

Scottish Cardiovascular Forum 2019

Ian Megson (Organiser)
1 Feb 2019

Activity: Participating in or organising an eventOrganising a conference

Departmental seminar

Ian Megson (Speaker)
3 Aug 2017

Activity: OtherTypes of Public engagement and outreach - Public lecture/debate/seminar

Scottish Cardiovascular Forum 2017

Ian Megson (Chair)
4 Feb 2017

Activity: Participating in or organising an eventParticipation in conference

Masteclasses for S1/S2 science pupils

Ian Megson (Presenter)
6 May 201713 May 2017

Activity: OtherTypes of Public engagement and outreach - Schools engagement

Departmental seminar

Ian Megson (Speaker)
3 Mar 2017

Activity: OtherTypes of External academic engagement - Invited talk

Press / Media

Nanotechnology professor appointed at university

Ian Megson

18/07/19

1 item of Media coverage

Press/Media: Research

Media release: Inverness welcomes cardiovascular experts

Ian Megson

4/02/19

1 item of Media coverage

Press/Media: Research

Trust Me I'm a Doctor

Ian Megson

19/09/0819/09/18

1 item of Media coverage, 1 Media contribution

Press/Media: Research

Thesis

Nanotoxicity of oxide-derived engineered nanomaterials: impact on cell viability and function, with conventional assays and evaluation of novel eicosanoid profiling

Author: Garrison, E., 1 Nov 2016

Supervisor: Megson, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy (awarded by OU/Aberdeen)

File

The impact of antipsychotic drugs on the expression of genes associated with obesity

Author: Mustard, C., 31 Jul 2016

Supervisor: Wei, J. (Supervisor), Megson, I. (Supervisor), Whitfield, P. D. (Supervisor) & Bermano, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy (awarded by OU/Aberdeen)

File

Role and mechanism of action of the anthocyanin, delphinidin, in protecting endothelial cells against oxidative stress

Author: Goszcz, K., 31 Jul 2016

Supervisor: Megson, I. (Supervisor), Stewart, D. (Supervisor) & Duthie, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy (awarded by OU/Aberdeen)

File

A Genetic Analysis of the Relationship between Gluten Intolerance and Schizophrenia

Author: Bradford, M., 12 Feb 2012

Supervisor: Wei, J. (Supervisor), Megson, I. (Supervisor) & Shaw, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy (awarded by OU/Aberdeen)

File

Genetic association between schizophrenia and type-2 diabetes

Author: Mathur, A., 25 Nov 2011

Supervisor: Wei, J. (Supervisor), Megson, I. (Supervisor), Shaw, D. J. (Supervisor) & Law, M. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy (awarded by OU/Aberdeen)

File