Ian Megson

Personal profile

Research expertise

As the Head of Health Research & Innovation at the University of the Highlands & Islands, I oversee the activities of the various research teams, with a particular remit to direct the activities of the members of the Division of Biomedical Sciences. As well as supervising my research team, I am responsible for the departmental budget and for management of those research grants for which I am designated principal investigator. I am also ultimately responsible for the health and safety of my team members. My role includes a remit to design and deliver the strategy for curriculum development and research for the School of Health at the university. I am also a Visiting Professor at Robert Gordon University.

The focus of my research is the role of nitric oxide in vascular disease and the potential benefits of nitric oxide donor drugs as vasodilators, anti-platelet agents and anti-inflammatory agents. My interests include the interaction of nitric oxide with oxidant species and establishment of the importance of this interaction in the atherosclerotic process that underlies heart disease. Through collaboration with Prof Adriano Rossi (Centre for Inflammation Research, University of Edinburgh), I have expanded my research profile to encompass the role of NO in inflammatory cell apoptosis and, via several other collaborations, the therapeutic potential of NO in diseases as diverse as fungal toenail infection and trypanosomiasis. Furthermore, I have been involved in projects relating to acute renal failure (principle investigator), organ transplant (principal investigator), pre-eclampsia, and the potential benefits of novel coatings to prevent thrombosis in medical devices. The focus of our current research is shifting towards preventative medicine: I have ongoing projects associated with the health benefits of polyphenols and exercise. My research output is reflected in consistent publication of original papers and reviews in internationally recognised journals; my current h-factor is 46 (Scopus), 53 (Google Scholar).

In recognition of my contribution to these areas of cardiovascular science and to education as a whole, I have been awarded Fellowships with the Pharmacological Society, the Royal Biological Society and the Higher Education Academy.

LinkedIN profile

Researchgate profile

Education/Academic qualification

Doctor of Philosophy, University of St Andrews

Award Date: 1 Jan 1993

Bachelor of Science, University of St Andrews

Award Date: 1 Jan 1990

External positions

Member

Jun 2019 → …

Member, UK Ressearch and Innovation Future Leaders Fellowship Peer Review College

20 Aug 2018 → …

Associate Editor, Antioxidants

2018 → …

Fellow, British Pharmacological Society

2017 → …

Associate Editor

2014 → …

Visiting Professor, Robert Gordon University

2013 → …

Fellow

2012 → …

Fellow

2007 → …

Editorial Board

2006 → 2010

Honorary Research Fellow, The University of Edinburgh

2006 → 2018

Keywords

QP Physiology
Diabetes
Cardiovascular

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Projects

2 Finished
3 Not started
4 Active

Does polyphenol supplementation suppress the increase in oxidative stress and inflammation caused by reduced physical activity?

Crabtree, D., Megson, I., Hickson, K., Cobley, J., Goszcz, K., Muggeridge, D. & Gorely, T.

24/04/18 → …

Project: Research

File

967IM (ECME) A cross-border proposal for a New Eastern Corridor Medical Engineering Centre

Megson, I.

1/03/17 → 31/12/21

Project: Research

1048IM: Inverness and Highland City-Region Deal

Megson, I., Giangreco, A. & MacRury, S.

1/01/17 → 31/07/27

Project: Other

778JH HIE - Establishment of the School of Health and Wellbeing

Megson, I.

1/04/16 → 30/07/22

Project: Other

1673IM : Nanomaterials and photonic solutions: Novel ‘at source’ approaches to stop hospital-derived priority substances reaching the sewer network

Valdivia, M., Kean, A. & Megson, I.

1/10/20 → 30/09/24

Project: Other

COVID-19 in Scotland: a mathematical modelling approach to help understand the determining factors for case and mortality rates in a diverse population

Megson, I. & Husi, H.

Project: Research

Evaluation of a chronic obstructive pulmonary disease self-management tool for NHS Highland

Megson, I., Sage, D. B. & Giangreco, A.

Project: Consultancy

Research Output

7835 Citations
46 h-Index
137 Article
1 Chapter
1 Abstract
1 Meeting abstract
1 More
- 1 Book/Film/Article review

Radial artery access site complications during cardiac procedures, clinical implications and potential solutions: The role of nitric oxide

Coghill, E., Johnson, T., Morris, R., Leslie, S. & Megson, I., 26 Jan 2020, In : World Journal of Cardiology. 12, 1, p. 26 9 p.

Research output: Contribution to journal › Article

Open Access

File

4 Downloads (Pure)

Co-ingestion of antioxidant drinks with an unhealthy challenge meal fails to prevent post-prandial endothelial dysfunction: an open-label, crossover study in healthy older adults

Goszcz, K., Megson, I., Muggeridge, D., Treweeke, A., Hickson, K. & Adamson, J., 7 Mar 2019.

Research output: Contribution to conference › Abstract

Open Access

File

41 Downloads (Pure)

Co-ingestion of Antioxidant Drinks With an Unhealthy Challenge Meal Fails to Prevent Post-prandial Endothelial Dysfunction: An Open-Label, Crossover Study in Older Overweight Volunteers

Muggeridge, D., Goszcz, K., Treweeke, A., Adamson, J., Hickson, K., Crabtree, D. & Megson, I., 11 Oct 2019, In : Frontiers in Physiology. 10, p. 1293 1293.

Research output: Contribution to journal › Article

Open Access

File

21 Downloads (Pure)

Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease

Burtenshay, D., Kitching, M., Redmond, E., Megson, I. & Cahill, P., 2 Aug 2019, In : Frontiers in Cardiovascular Medicine. 6, 89.

Research output: Contribution to journal › Article

Open Access

File

7 Citations (Scopus)

34 Downloads (Pure)

Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer’s disease

Scipioni, M., Kay, G., Megson, I. & Kong, P., 1 May 2019, In : Medicinal Chemistry Communications. 10, 5, p. 764-777 14 p.

Research output: Contribution to journal › Article

Open Access

File

5 Citations (Scopus)

3 Downloads (Pure)

Associations between circulating IgG antibodies to Apolipoprotein B-derived peptide antigens and acute coronary syndrome in a Chinese Han population

Hu, W., Zhang, X., Han, Y., Wang, Y., Lei, M., Megson, I. L., Wei, J. & Jin, Y., Dec 2018, In : Bioscience Reports. 38, 6, p. 1-9 9 p., BSR20180450.

Research output: Contribution to journal › Article

Open Access

File

1 Citation (Scopus)

13 Downloads (Pure)

Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-haberle, I., Murphy, M. P., Moult, P. R. & Cobley, J. N., 20 Mar 2018, In : Redox Biology. 16, p. 344-351 8 p.

Research output: Contribution to journal › Article

Open Access

File