Projects per year
Personal profile
Research Expertise
As the Head of Health Research & Innovation at the University of the Highlands & Islands, I oversee the activities of the various research teams, with a particular remit to direct the activities of the members of the Division of Biomedical Sciences. As well as supervising my research team, I am responsible for the departmental budget and for management of those research grants for which I am designated principal investigator. I am also ultimately responsible for the health and safety of my team members. My role includes a remit to design and deliver the strategy for curriculum development and research for the School of Health at the university. I am also a Visiting Professor at Robert Gordon University.
The focus of my research is the role of nitric oxide in vascular disease and the potential benefits of nitric oxide donor drugs as vasodilators, anti-platelet agents and anti-inflammatory agents. My interests include the interaction of nitric oxide with oxidant species and establishment of the importance of this interaction in the atherosclerotic process that underlies heart disease. Through collaboration with Prof Adriano Rossi (Centre for Inflammation Research, University of Edinburgh), I have expanded my research profile to encompass the role of NO in inflammatory cell apoptosis and, via several other collaborations, the therapeutic potential of NO in diseases as diverse as fungal toenail infection and trypanosomiasis. Furthermore, I have been involved in projects relating to acute renal failure (principle investigator), organ transplant (principal investigator), pre-eclampsia, and the potential benefits of novel coatings to prevent thrombosis in medical devices. The focus of our current research is shifting towards preventative medicine: I have ongoing projects associated with the health benefits of polyphenols and exercise. Current research includes looking at why COVID-19 seems more severe in patients with diabetes and tracking of long-COVID symptoms to begin to identify the underlying mechanisms and inflammatory system responses.
My research output is reflected in consistent publication of original papers and reviews in internationally recognised journals; my current h-factor is 50 (Scopus), 56 (Google Scholar).
In recognition of my contribution to these areas of cardiovascular science and to education as a whole, I have been awarded Fellowships with the Pharmacological Society, the Royal Biological Society and the Higher Education Academy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of St Andrews
Award Date: 1 Jan 1993
Bachelor of Science, University of St Andrews
Award Date: 1 Jan 1990
External positions
Member, Chief Scientist Office
Jun 2019 → …
Member, UK Ressearch and Innovation Future Leaders Fellowship Peer Review College
20 Aug 2018 → …
Associate Editor, Antioxidants
2018 → …
Fellow, British Pharmacological Society
2017 → …
Associate Editor, Frontiers in Cardiovascular Medicine
2014 → …
Visiting Professor, Robert Gordon University
2013 → …
Fellow, Royal Society of Biology
2012 → …
Fellow, Higher Education Academy
2007 → …
Editorial Board, British Journal of Pharmacology
2006 → 2010
Honorary Research Fellow, University of Edinburgh
2006 → 2018
Keywords
- QP Physiology
- Diabetes
- Cardiovascular
- REF 03
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Collaborations from the last five years
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Does polyphenol supplementation suppress the increase in oxidative stress and inflammation caused by reduced physical activity?
Crabtree, D. R., Megson, I., Hickson, K., Cobley, J., Goszcz, K., Muggeridge, D. & Gorely, T.
24/04/18 → …
Project: Research
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1048IM: Inverness and Highland City-Region Deal
Megson, I., Giangreco, A. & MacRury, S.
1/01/17 → 31/07/27
Project: Other
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Evaluation of a chronic obstructive pulmonary disease self-management tool for NHS Highland
Megson, I., Sage, D. B. & Giangreco, A.
Project: Consultancy
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An active nano-surface for the detection of airborne hospital pathogens by optical spectroscopy (NAPOS)
25/06/21 → 24/12/21
Project: Research
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Is there a correlation between self-reported fatigue and biomarkers for fatigue in low risk breast cancer?
1/06/21 → 30/11/21
Project: Research
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First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses
Andrews, J. P. M., Joshi, S. S., Tzolos, E., Syed, M. B., Cuthbert, H., Crica, L. E., Lozano, N., Okwelogu, E., Raftis, J. B., Bruce, L., Poland, C. A., Duffin, R., Fokkens, P. H. B., Boere, A. J. F., Leseman, D. L. A. C., Megson, I. L., Whitfield, P. D., Ziegler, K., Tammireddy, S., Hadjidemetriou, M., & 5 others , 16 Feb 2024, In: Nature Nanotechnology. 67, S1, p. i52-i53 1 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)18 Downloads (Pure) -
At-Source Hospital Wastewater Treatment to Eliminate Harmful Pharmaceuticals: A Novel Immobilised Approach Using UV-LED Activated Photocatalytic Nanomaterials
Valdivia, M., Taggart, M. A., Pap, S., Kean, A. & Megson, I. L., 30 Nov 2023. 2 p.Research output: Contribution to conference › Paper › peer-review
Open AccessFile33 Downloads (Pure) -
Blue light photoinhibition of Streptococcus mutans: potential chromophores and mechanisms
Mohamad, S. A., Megson, I. L. & Kean, A. H., 1 Nov 2023, In: Lasers in Dental Science.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Photocatalytic metallic nanomaterials immobilised onto porous structures: Future perspectives for at-source pharmaceutical removal from hospital wastewater and potential benefits over existing technologies
Valdivia, M-T., Taggart, M., Pap, S., Kean, A., Pfleger, S. & Megson, I., 1 Apr 2023, In: Journal of water process engineering. 52, 103553.Research output: Contribution to journal › Review article › peer-review
Open AccessFile13 Citations (Scopus)100 Downloads (Pure) -
Acetylcysteine has No Mechanistic Effect in Patients at Risk of Contrast-Induced Nephropathy - A Failure of Academic Clinical Science
Sandilands, E. A., Rees, J., Khuram, R., Dhuan, N., Morrison, E., Hickson, K., Wraight, J., Gray, T., Briody, L., Cameron, S., Thompson, A., Johnston, N., Uren, N., Goddard, J., Treweeke, A., Rushworth, G., Webb, D. J., Bateman, D. N., Norrie, J., Megson, I., & 1 others , 24 Feb 2022, In: Clinical Pharmacology and Therapeutics. 111, 6, p. 1222-1238 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)43 Downloads (Pure) -
Clinical and health economic evaluation of a post stroke arrhythmia monitoring service
Muggeridge, D., Callum, K., Macpherson, L., Howard, N., Graune, C., Megson, I., Giangreco, A., Gallacher, S., Campbell, L., Williams, G., Macaden, A. & Leslie, S. J., 31 May 2022, In: British Journal of Cardiology. 29, 2, p. 46-51 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile77 Downloads (Pure) -
Exercise decreases PP2A-specific reversible thiol oxidation in human erythrocytes: Implications for redox biomarkers
Muggeridge, D., Crabtree, D. R., Tuncay, A., Megson, I., Davison, G. W. & Cobley, J., 30 Mar 2022, In: Free Radical Biology & Medicine. 182, p. 73-78 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)54 Downloads (Pure)
Prizes
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SCDI Highlands and Islands Enterprise Award for Excellence in Research and Innovation
Megson, Ian (Recipient) & Giangreco, Adam (Recipient), Sept 2019
Prize: Prize (including medals and awards)
Activities
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Scottish Cardiovascular Forum 2019
Ian Megson (Organiser)
1 Feb 2019Activity: Participating in or organising an event › Organising a conference
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Departmental seminar
Ian Megson (Speaker)
3 Aug 2017Activity: KE and Outreach activities › Types of Public engagement and outreach - Public lecture/debate/seminar
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Departmental seminar
Ian Megson (Speaker)
3 Mar 2017Activity: KE and Outreach activities › Types of External academic engagement - Invited talk
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Scottish Cardiovascular Forum 2017
Ian Megson (Chair)
4 Feb 2017Activity: Participating in or organising an event › Participation in conference
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Masteclasses for S1/S2 science pupils
Ian Megson (Presenter)
6 May 2017 → 13 May 2017Activity: KE and Outreach activities › Types of Public engagement and outreach - Schools engagement
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UHI Research Conference 2016
Ian Megson (Chair)
7 Nov 2016 → 9 Nov 2016Activity: Participating in or organising an event › Participation in conference
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NHS Highland Research, Development & Innovation Conference 2016
Ian Megson (Participant)
25 Nov 2016Activity: Participating in or organising an event › Participation in conference
Press/Media
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Researcher at University of Edinburgh Publishes New Data on Multiple Sclerosis (Fatigue in early multiple sclerosis; MRI metrics of neuroinflammation, relapse and neurodegeneration)
2/09/24
1 item of Media coverage
Press/Media: Research
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Study to Measure Cell-Free DNA Capture Potential of BioCaptis Device
Ian Megson & Antonia Pritchard
15/12/23
1 item of Media coverage
Press/Media: Research
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Biocaptiva to conduct ex-vivo study to evaluate potential of BioCaptis device to capture cell free DNA to improve pleural disease diagnosis
Ian Megson & Antonia Pritchard
16/10/23
1 item of Media coverage
Press/Media: Research
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Biocaptiva to conduct ex-vivo study to evaluate potential of BioCaptis device to capture cell free DNA to improve pleural disease diagnosis
Ian Megson & Antonia Pritchard
16/10/23
1 item of Media coverage
Press/Media: Research
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BIOCAPTIVA To Conduct Ex-Vivo Study To Evaluate The Potential Of The Biocaptis Device To Capture Cell Free DNA To Improve Pleural Disease Diagnosis
Ian Megson & Antonia Pritchard
12/10/23
1 item of Media coverage
Press/Media: Research
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BIOCAPTIVA to conduct ex-vivo study to evaluate the potential of the BioCaptis device to capture cell free DNA to improve pleural disease diagnosis
Ian Megson & Antonia Pritchard
12/10/23
123 items of Media coverage
Press/Media: Research
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