Projects per year
Personal profile
Academic Qualifications
B.Med.Sc (1st class honours; specialisation in cellular and molecular biology)
Ph.D (Psychiatry; Genetics of Alzheimer's Disease)
Research expertise
Dr Pritchard's research group investigates three main areas, centred around the study of melanoma. These include:
a) The genetics of melanoma susceptibility: what makes someone more likely to develop melanoma? What increases the risk of melanoma development in certain families?
b) The genomics of melanoma: what changes to the genome of melanoma drive the initiation, development and progression of melanomas?
c) The immunological control of melanoma: how does the immune system recognise melanoma cells? How do melanoma cells escape the immune system control?
Dr Pritchard's research group is interested in all types of melanoma, including skin, acral (sole of feet/palm of hands and fingernail beds), uveal (eye) and mucosal (e.g. oral, nasal, rectal) melanomas.
Research links
Google Scholar: Antonia Pritchard
Web of Science ResearcherID: F-4288-2010
ORCID: 0000-0001-5336-0454
Twitter: @antoniagage
External positions
Visiting Scientist
Jul 2017 → …Fingerprint
Network
Projects
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Identification of tumour reactive T cells in peripheral blood
Pritchard, A. & Hutchison, S.
20/01/20 → 31/03/21
Project: Research
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Drug screen to identify therapeutic targets for acral lentiginous melanoma
Pritchard, A., Broit, N., Hayward, N. K. & Boyle, G.
Therapeutic Innovation Australia
8/01/20 → 10/01/22
Project: Research
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Development of 3-dimensional models of uveal melanoma
Pritchard, A. & Hutchison, S.
3/09/19 → 31/12/20
Project: Research
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Identification of genetic predisposition to familial melanoma and related cancers
Pritchard, A., Mustard, C. & Hutchison, S.
1/08/17 → …
Project: Research
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The T-cell immune response to melanoma
Pritchard, A., Hutchison, S. & Mustard, C.
1/08/17 → …
Project: Research
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Research Output
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Attack of the Subclones: Accurate Detection of Mutational Heterogeneity in Bulk DNA from Tumors
Rodgers, C. B., Broit, N., Johansson, P. A. & Pritchard, A. L., 1 Aug 2020, In : Journal of Investigative Dermatology. 140, 8, p. 1501-1503 3 p.Research output: Contribution to journal › Comment/debate
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FRAMe: Familial Risk Assessment of Melanoma—a risk prediction tool to guide CDKN2A germline mutation testing in Australian familial melanoma
Holland, E. A., Lo, S., Kelly, B., Schmid, H., Cust, A. E., Palmer, J. M., Drummond, M., Hayward, N. K., Pritchard, A. L. & Mann, G. J., 29 Sep 2020, In : Familial Cancer.Research output: Contribution to journal › Article
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Loss-of-function variants in POT1 predispose to uveal melanoma
Nathan, V., Palmer, J. M., Johansson, P. A., Hamilton, H. R., Warrier, S. K., Glasson, W., McGrath, L. A., Kahl, V. F. S., Vasireddy, R. S., Pickett, H. A., Brooks, K. M., Pritchard, A. L. & Hayward, N. K., 9 Sep 2020, In : Journal of Medical Genetics.Research output: Contribution to journal › Article
Open AccessFile3 Downloads (Pure) -
Multiplex melanoma families are enriched for polygenic risk
27 Jul 2020, In : Human Molecular Genetics. 29, 17, p. 2976-2985 10 p.Research output: Contribution to journal › Article
Open AccessFile -
Pan-cancer analysis of whole genomes
Pritchard, A., 5 Feb 2020, In : Nature. 578, 7793, p. 82-93 12 p.Research output: Contribution to journal › Article
Open AccessFile193 Citations (Scopus)4 Downloads (Pure) -
Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours
Johansson, P. A., Brooks, K., Newell, F., Palmer, J. M., Wilmott, J. S., Pritchard, A. L., Broit, N., Wood, S., Carlino, M. S., Leonard, C., Koufariotis, L. T., Nathan, V., Beasley, A. B., Howlie, M., Dawson, R., Rizos, H., Schmidt, C. W., Long, G. V., Hamilton, H., Kiilgaard, J. F. & 15 others, , 15 May 2020, In : Nature Communications. 11, p. 1-8 8 p., 2408 (2020).Research output: Contribution to journal › Article
Open AccessFile5 Citations (Scopus)20 Downloads (Pure) -
Bone marrow transplantation generates T cell-dependent control of myeloma in mice
Vuckovic, S., Minnie, S. A., Smith, D., Gartlan, K. H., Watkins, T. S., Markey, K. A., Mukhopadhyay, P., Guillerey, C., Kuns, R. D., Locke, K. R., Pritchard, A. L., Johansson, P. A., Varelias, A., Zhang, P., Huntington, N. D., Waddell, N., Chesi, M., Miles, J. J., Smyth, M. J. & Hill, G. R., 2 Jan 2019, In : Journal of Clinical Investigation. 129, 1, p. 106-121 16 p.Research output: Contribution to journal › Article
12 Citations (Scopus)
Activities
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Women in STEM panel
Antonia Pritchard (Speaker)
3 Aug 2019Activity: Talk or presentation › Invited talk
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Scottish Skin Cancer Meeting
Antonia Pritchard (Participant)
15 Mar 2018Activity: Participating in or organising an event › Participation in conference
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Genetics of Familial Melanoma
Antonia Pritchard (Speaker)
12 Jan 2018Activity: Talk or presentation › Invited talk
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Skin cancer genomics
Antonia Pritchard (Speaker)
17 Jul 2018Activity: Talk or presentation › Invited talk
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Upstream deletion: is it associated with familial melanoma?
Antonia Pritchard (Speaker)
19 Mar 2018 → 23 Mar 2018Activity: Talk or presentation › Invited talk
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U-V's the sun: the battle against skin cancer
Antonia Pritchard (Speaker)
27 Apr 2018Activity: Talk or presentation › Invited talk
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RSE@Inverness
Antonia Pritchard (Member)
30 Sep 2017Activity: Other › Types of Public engagement and outreach - Festival/Exhibition
Press / Media
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Friend takes on gruelling challenges in memory of Stirling doctor; Louise Harper will put herself through a cycle race around Loch Lomond and a hike up Mount Kilimanjaro to pay tribute to Sharon Hutchison, who passed away from melanoma - the very conditio
21/02/20
1 item of Media coverage
Press/Media: Research
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DoingitforSharon; Pals'tribute to doctor who died of illness she was trying to find cure for
19/02/20
1 item of Media coverage
Press/Media: Research
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TOP DOC KILLED BY CANCER SHE WAS FIGHTING TO CURE; family and friends pay tribute ; Colleague says Sharon's dedication will inspire them as they continue her work
16/01/20
1 item of Media coverage
Press/Media: Research
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Sharon lived and loved life to the full; HEARTFELT TRIBUTES TO DOCTOR ; Death is cruel twist of fate
15/01/20
1 item of Media coverage
Press/Media: Research
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'Meticulous' Melanoma Researcher Dies From the Disease
14/01/20
2 items of Media coverage
Press/Media: Research