Antonia Pritchard

Doctor

  • IV2 3JH

    United Kingdom

Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
20032023

Research activity per year

Personal profile

Academic Qualifications

B.Med.Sc (1st class honours; specialisation in cellular and molecular biology)

Ph.D (Psychiatry; Genetics of Alzheimer's Disease)

Research Expertise

Dr Pritchard's research group investigates three main areas, centred around the study of melanoma. These include:

a) The genetics of melanoma susceptibility: what makes someone more likely to develop melanoma? What increases the risk of melanoma development in certain families?

b) The genomics of melanoma: what changes to the genome of melanoma drive the initiation, development and progression of melanomas?

c) The immunological control of melanoma: how does the immune system recognise melanoma cells? How do melanoma cells escape the immune system control?

Dr Pritchard's research group is interested in all types of melanoma, including skin, acral (sole of feet/palm of hands and fingernail beds), uveal (eye) and mucosal (e.g. oral, nasal, rectal) melanomas.

Research links

Google Scholar: Antonia Pritchard

Web of Science ResearcherID: F-4288-2010

ORCID: 0000-0001-5336-0454

Twitter: @antoniagage

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

External positions

Visiting Scientist, Oncogenomics Group, QIMR Berghofer Medical Research Institute, Brisbane, Australia.

Jul 2017 → …

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Collaborations from the last five years

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  • Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours

    Johansson, P. A., Brooks, K., Newell, F., Palmer, J. M., Wilmott, J. S., Pritchard, A. L., Broit, N., Wood, S., Carlino, M. S., Leonard, C., Koufariotis, L. T., Nathan, V., Beasley, A. B., Howlie, M., Dawson, R., Rizos, H., Schmidt, C. W., Long, G. V., Hamilton, H., Kiilgaard, J. F., & 15 othersIsaacs, T., Gray, E. S., Rolfe, O. J., Park, J. J., Stark, A., Mann, G. J., Scolyer, R. A., Pearson, J. V., Van Baren, N., Waddell, N., Wadt, K. W., Mcgrath, L. A., Warrier, S. K., Glasson, W. & Hayward, N. K., 15 May 2020, In: Nature Communications. 11, p. 1-8 8 p., 2408 (2020).

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    87 Citations (Scopus)
    109 Downloads (Pure)
  • Whole-genome landscapes of major melanoma subtypes

    Hayward, N. K., Wilmott, J. S., Waddell, N., Johansson, P. A., Field, M. A., Nones, K., Patch, A-M., Kakavand, H., Alexandrov, L. B., Burke, H., Jakrot, V., Kazakoff, S., Holmes, O., Leonard, C., Sabarinathan, R., Mularoni, L., Wood, S., Xu, Q., Waddell, N., Tembe, V., & 29 othersPupo, G. M., De Paoli-Iseppi, R., Vilain, R. E., Shang, P., Lau, L. M. S., Dagg, R. A., Schramm, S-J., Pritchard, A., Dutton-Regester, K., Newell, F., Fitzgerald, A., Shang, C. A., Grimmond, S. M., Pickett, H. A., Yang, J. Y., Stretch, J. R., Behren, A., Kefford, R. F., Hersey, P., Long, G. V., Cebon, J., Shackleton, M., Spillane, A. J., Saw, R. P. M., Lopez-Bigas, N., Pearson, J. V., Thompson, J. F., Scolyer, R. A. & Mann, G. J., 11 May 2017, In: Nature. 545, 7653, p. 175-180 6 p.

    Research output: Contribution to journalArticlepeer-review

    958 Citations (Scopus)
  • Exploration of peptides bound to MHC class I molecules in melanoma

    Pritchard, A. L., Hastie, M. L., Neller, M., Gorman, J. J., Schmidt, C. W. & Hayward, N. K., May 2015, In: Pigment Cell and Melanoma Research. 28, 3, p. 281-294 14 p.

    Research output: Contribution to journalArticlepeer-review

    19 Citations (Scopus)
  • Exome Sequencing to Predict Neoantigens in Melanoma

    Pritchard, A. L., Burel, J. G., Neller, M. A., Hayward, N. K., Lopez, J. A., Fatho, M., Lennerz, V., Woelfel, T. & Schmidt, C. W., Sept 2015, In: Cancer Immunology Research. 3, 9, p. 992-998 7 p.

    Research output: Contribution to journalArticlepeer-review

    47 Citations (Scopus)
  • Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma

    Aoude, L. G., Pritchard, A. L., Robles-Espinoza, C. D., Wadt, K., Harland, M., Choi, J., Gartside, M., Quesada, V., Johansson, P. A., Palmer, J. M., Ramsay, A. J., Zhang, X., Jones, K., Symmons, J., Holland, E. A., Schmid, H., Bonazzi, V., Woods, S., Dutton-Regester, K., Stark, M. S., & 19 othersSnowden, H., van Doom, R., Montgomery, G. W., Martin, N. G., Keane, T. M., Lopez-Otin, C., Gerdes, A-M., Olsson, H., Ingvar, C., Borg, A., Gruis, N. A., Trent, J. M., Jonsson, G., Bishop, D. T., Mann, G. J., Newton-Bishop, J. A., Brown, K. M., Adams, D. J. & Hayward, N. K., 1 Feb 2015, In: JNCI: Journal of the National Cancer Institute. 107, 2, 7 p.

    Research output: Contribution to journalArticlepeer-review

    138 Citations (Scopus)
  • POT1 loss-of-function variants predispose to familial melanoma

    Robles-Espinoza, C. D., Harland, M., Ramsay, A. J., Aoude, L. G., Quesada, V., Ding, Z., Pooley, K. A., Pritchard, A. L., Tiffen, J. C., Petljak, M., Palmer, J. M., Symmons, J., Johansson, P. A., Stark, M. S., Gartside, M. G., Snowden, H., Montgomery, G. W., Martin, N. G., Lite, J. Z., Choi, J., & 10 othersMakowski, M., Brown, K. M., Dunning, A. M., Keane, T. M., Lopez-Otin, C., Gruis, N. A., Hayward, N. K., Bishop, D. T., Newton-Bishop, J. A. & Adams, D. J., May 2014, In: Nature Genetics. 46, 5, p. 478-481 4 p.

    Research output: Contribution to journalArticlepeer-review

    299 Citations (Scopus)
  • Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x)

    Yuan, Y., Ju, Y. S., Kim, Y., Li, J., Wang, Y., Yoon, C. J., Yang, Y., Martincorena, I., Creighton, C. J., Weinstein, J. N., Xu, Y., Han, L., Kim, H. L., Nakagawa, H., Park, K., Campbell, P. J., Liang, H., Aaltonen, L. A., Abascal, F., Abeshouse, A., & 30 othersAburatani, H., Adams, D. J., Agrawal, N., Ahn, K. S., Ahn, S. M., Aikata, H., Akbani, R., Akdemir, K. C., Al-Ahmadie, H., Al-Sedairy, S. T., Al-Shahrour, F., Alawi, M., Albert, M., Aldape, K., Alexandrov, L. B., Ally, A., Alsop, K., Alvarez, E. G., Amary, F., Amin, S. B., Aminou, B., Ammerpohl, O., Anderson, M. J., Ang, Y., Antonello, D., Anur, P., Aparicio, S., Appelbaum, E. L., Arai, Y. & Pritchard, A. L., 21 Mar 2023, In: Nature Genetics. 55, 6, 1 p., 1078 (2023).

    Research output: Contribution to journalComment/debatepeer-review

    Open Access