No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample

Heyao Li; Haiying Zhang; Libo Liu; Guizhi Ju; Shunzi Jin; Lin Ye; Xuan Zhang; Jun Wei

doi:10.1016/j.psychres.2008.11.004

No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample

Heyao Li
, Haiying Zhang
, Libo Liu
, Guizhi Ju
, Shunzi Jin
, Lin Ye
, Xuan Zhang
, Jun Wei

Publikation: Article › Begutachtung

2 Zitate (Scopus)

Abstract

The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.

Originalsprache	English
Seiten (von - bis)	176-7
Seitenumfang	2
Fachzeitschrift	Psychiatry Research
Jahrgang	169
Ausgabenummer	2
DOIs	https://doi.org/10.1016/j.psychres.2008.11.004
Publikationsstatus	Published - 30 Sept. 2009

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10.1016/j.psychres.2008.11.004

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title = "No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample",

abstract = "The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.",

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author = "Heyao Li and Haiying Zhang and Libo Liu and Guizhi Ju and Shunzi Jin and Lin Ye and Xuan Zhang and Jun Wei",

year = "2009",

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doi = "10.1016/j.psychres.2008.11.004",

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AU - Li, Heyao

AU - Zhang, Haiying

AU - Liu, Libo

AU - Ju, Guizhi

AU - Jin, Shunzi

AU - Ye, Lin

AU - Zhang, Xuan

AU - Wei, Jun

PY - 2009/9/30

Y1 - 2009/9/30

N2 - The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.

AB - The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.

KW - Adult

KW - Asian Continental Ancestry Group

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Female

KW - Gene Frequency

KW - Genetic Predisposition to Disease

KW - Genotype

KW - Humans

KW - Male

KW - Middle Aged

KW - Phosphatidylethanolamine N-Methyltransferase

KW - Polymorphism, Single Nucleotide

KW - Schizophrenia

KW - Young Adult

U2 - 10.1016/j.psychres.2008.11.004

DO - 10.1016/j.psychres.2008.11.004

M3 - Article

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SN - 0165-1781

VL - 169

SP - 176

EP - 177

JO - Psychiatry Research

JF - Psychiatry Research

IS - 2

ER -

No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample

Abstract

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