N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

A T Treweeke; T J Winterburn; I Mackenzie; F Barrett; C Barr; G F Rushworth; I Dransfield; S M Macrury; I L Megson

doi:10.1007/s00125-012-2685-z

N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

A T Treweeke
, T J Winterburn
, I Mackenzie
, F Barrett
, C Barr
, G F Rushworth
, I Dransfield
, S M Macrury
, I L Megson

Publikation: Article › Begutachtung

42 Zitate (Scopus)

Abstract

The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

Originalsprache	English
Seiten (von - bis)	2920-8
Seitenumfang	9
Fachzeitschrift	Diabetologia
Jahrgang	55
Ausgabenummer	11
DOIs	https://doi.org/10.1007/s00125-012-2685-z
Publikationsstatus	Published - 2012

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10.1007/s00125-012-2685-z

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Treweeke, A. T., Winterburn, T. J., Mackenzie, I., Barrett, F., Barr, C., Rushworth, G. F., Dransfield, I., Macrury, S. M., & Megson, I. L. (2012). N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial. Diabetologia, 55(11), 2920-8. https://doi.org/10.1007/s00125-012-2685-z

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abstract = "The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.",

author = "Treweeke, \{A T\} and Winterburn, \{T J\} and I Mackenzie and F Barrett and C Barr and Rushworth, \{G F\} and I Dransfield and Macrury, \{S M\} and Megson, \{I L\}",

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Treweeke, AT, Winterburn, TJ, Mackenzie, I, Barrett, F, Barr, C, Rushworth, GF, Dransfield, I, Macrury, SM & Megson, IL 2012, 'N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial', Diabetologia, Jg. 55, Nr. 11, S. 2920-8. https://doi.org/10.1007/s00125-012-2685-z

TY - JOUR

T1 - N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione

T2 - a randomised controlled trial

AU - Treweeke, A T

AU - Winterburn, T J

AU - Mackenzie, I

AU - Barrett, F

AU - Barr, C

AU - Rushworth, G F

AU - Dransfield, I

AU - Macrury, S M

AU - Megson, I L

PY - 2012

Y1 - 2012

N2 - The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

AB - The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet-monocyte conjugation in blood from patients with type 2 diabetes.

U2 - 10.1007/s00125-012-2685-z

DO - 10.1007/s00125-012-2685-z

M3 - Article

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SN - 1432-0428

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SP - 2920

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JO - Diabetologia

JF - Diabetologia

IS - 11

ER -

N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

Abstract

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