Effect of seven anti-tuberculosis treatment regimens on sputum microbiome:: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

Emmanuel Musisi; Adam Wyness; Wilber Sabiiti

doi:10.1016/S2666-5247(23)00191-X

Effect of seven anti-tuberculosis treatment regimens on sputum microbiome: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

, Emmanuel Musisi
, Adam Wyness
, Wilber Sabiiti

SAMS UHI

Publikation: Article › Begutachtung

11 Zitate (Scopus)

Abstract

Respiratory tract microbiota has been described as the gatekeeper for respiratory health. We aimed to assess the impact of standard-of-care and experimental anti-tuberculosis treatment regimens on the respiratory microbiome and implications for treatment outcomes.

Originalsprache	English
Seiten (von - bis)	e913-e922
Seitenumfang	10
Fachzeitschrift	The Lancet Microbe
Jahrgang	4
Ausgabenummer	11
DOIs	https://doi.org/10.1016/S2666-5247(23)00191-X
Publikationsstatus	Published - 1 Nov. 2023

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10.1016/S2666-5247(23)00191-XLizenz: CC BY

https://linkinghub.elsevier.com/retrieve/pii/S266652472300191X

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abstract = "Respiratory tract microbiota has been described as the gatekeeper for respiratory health. We aimed to assess the impact of standard-of-care and experimental anti-tuberculosis treatment regimens on the respiratory microbiome and implications for treatment outcomes.",

author = "Emmanuel Musisi and Adam Wyness and Sahar Eldirdiri and Evelin Dombay and Bariki Mtafya and Ntinginya, \{Nyanda e\} and Norbert Heinrich and Kibiki, \{Gibson s\} and Michael Hoelscher and Martin Boeree and Rob Aarnoutse and Gillespie, \{Stephen h\} and Wilber Sabiiti and Emmanuel Musisi and Bariki Mtafya and Ntinginya, \{Nyanda e.\} and Norbert Heinrich and Kibiki, \{Gibson s.\} and Michael Hoelscher and Martin Boeree and Stephen Gillespie and Wilber Sabiiti and Derek Sloan and Larissa Hoffmann and Ivan Nore{\~n}a and Wandini Lutchmun and Julia Dreisbach and Demel,, \{Petra gross\} and Andrea Kelly and Brake, \{Lindsey te\} and Elin Svensson and Rob Aarnoutse and Isobella Honeyborne and Wildner, \{Leticia muraro\} and Robert Hunt and Mchugh, \{Timothy d.\} and Nunn, \{Andrew j\} and Phillips, \{Patrick p.j.\} and Xue Gong and Rodney Dawson and Kim Narunsky and Andreas Diacon and \{De jager\}, Veronique and Sven Friedrich and Ian Sanne and Mohammed Rassool and Chacha Mangu and Christina Manyama and Issa Sabi and Minja, \{Lilian t.\}",

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AU - Ntinginya, Nyanda e

AU - Heinrich, Norbert

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AU - Musisi, Emmanuel

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AU - Heinrich, Norbert

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AU - Hoelscher, Michael

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AU - Dreisbach, Julia

AU - Demel,, Petra gross

AU - Kelly, Andrea

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AU - Svensson, Elin

AU - Aarnoutse, Rob

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AU - Mchugh, Timothy d.

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AU - Sanne, Ian

AU - Rassool, Mohammed

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AU - Sabi, Issa

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DO - 10.1016/S2666-5247(23)00191-X

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Effect of seven anti-tuberculosis treatment regimens on sputum microbiome: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

Abstract

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